Cell-based assays for high-throughput screening : methods and protocols

Bibliographic Details
Main Authors: Clemons, Paul A. (Author), Tolliday, Nicola J. (Author), Wagner, Bridget K. (Author)
Format: Book
Language:English
Published: New York : Humana , c2009
Series:Methods in molecular biology v. 486
Springer protocols
Subjects:

MARC

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008 090624s2008 nyu eng
020 |a 1603275444 (hbk. : alk. paper) 
020 |a 1603275452 (e-ISBN) 
020 |a 9781603275446 (hbk. : alk. paper) 
020 |a 9781603275453 (e-ISBN) 
050 0 0 |a RS419.5   |b .C45 2009 
060 1 0 |a QV 25   |b C395 2009 
090 0 0 |a QV 25   |b C395 2009 
245 0 0 |a Cell-based assays for high-throughput screening :   |b methods and protocols   |c edited by Paul A. Clemons, Nicola J. Tolliday, and Bridget K. Wagner 
260 |a New York :   |b Humana ,   |c c2009 
300 |a x, 218 p. :   |b ill. ;   |c 26 cm. 
440 0 |a Methods in molecular biology   |x 1064-3745   |v v. 486 
440 0 |a Springer protocols 
504 |a Includes bibliographical references and index 
505 0 |a 1. Introduction: cell-based assays for high-throughput screening -- 2. High-throughput screening of model bacteria -- 3. Cell-based assays to probe teh ERK MAP kinase -- 4. Large-scale small-molecule screen using Zebrafish Embryos -- 5. Whole-animal high-throughput screens: the C. elegans model -- 6. Whole-organism screening: plants -- 7. Fluorescence-based assays -- 8. Reporter gene assays -- 9. Screening for chemical inhibitors of heterologous proteins expressed in yeast using a simple growth-restoration assay -- 10. Assay for isolution of inhibitorsof Her2-kinase expression -- 11. High-content screening: flow cytometry analysis -- 12. High-throughput real-time PCR for detection -- 13. Interpretation of uniform-well readouts -- 14. Extracting rich information from images 
650 0 |a Biological assay 
650 0 |a High throughput screening (Drug development) 
650 1 2 |a Drug Discovery 
650 2 2 |a Biological assay 
650 2 2 |a Drug Evaluation, Preclinical 
655 2 |a Laboratory Manuals 
700 1 |a Clemons, Paul A. ,   |e author 
700 1 |a Tolliday, Nicola J. ,   |e author 
700 1 |a Wagner, Bridget K. ,   |e author 
999 |a 1000128523   |b Book   |c OPEN SHELF (30 DAYS)   |e Medical Campus