Animal cell biotechnology : methods and protocols

Bibliographic Details
Main Author: Portner, Ralf (Author)
Format: Book
Language:English
Published: Totowa, NJ : Humana Press , 2007
Edition:2nd ed
Series:Methods in biotechnology 24
Subjects:
Online Access:Table of contents only
Publisher description
Table of Contents:
  • Part I. Basic Techniques for Establishing Production Cell Lines
  • 1. Transduction Technologies / David A. Fluri and Martin Fussenegger
  • 2. Cells for Gene Therapy and Vector Production / Christophe Delenda, Miguel Chillon, Anne-Marie Douar and Otto-Wilhelm Merten
  • 3. Technology and Production of Murine Monoclonal and Recombinant Antibodies and Antibody Fragments / Alexandra Dorn-Beineke, Stefanie Nittka and Michael Neumaier
  • 4. DNA Fingerprinting and Characterization of Animal Cell Lines / Glyn N. Stacey, Ed Byrne and J. Ross Hawkins
  • Part II. Basic Cultivation Techniques
  • 5. Microcarrier Cell Culture Technology / Gerald Bluml
  • 6. Cell Encapsulation / Holger Hubner
  • 7. Tools for High-Throughput Medium and Process Optimization / Martin Jordan and Nigel Jenkins
  • Part III. Cell Characterization and Analysis
  • 8. Cell Counting and Viability Measurements / Michael Butler and Maureen Spearman
  • 9. Monitoring of Growth, Physiology, and Productivity of Animal Cells by Flow Cytometry / Silvia Carroll, Mariam Naeiri and Mohamed Al-Rubeai
  • 10. Nuclear Magnetic Resonance Methods for Monitoring Cell Growth and Metabolism in Intensive Bioreactors / Andre A. Neves and Kevin M. Brindle
  • 11. Methods for Off-Line Analysis of Nutrients and Products in Mammalian Cell Culture / Heino Buntemeyer
  • 12. Application of Stoichiometric and Kinetic Analyses to Characterize Cell Growth and Product Formation / Derek Adams, Rashmi Korke and Wei-Shou Hu
  • 13. Measurement of Apoptosis in Cell Culture / Adiba Ishaque and Mohamed Al-Rubeai
  • 14. Metabolic Flux Estimation in Mammalian Cell Cultures / Chetan T. Goudar, Richard Biener, James M. Piret and Konstantin B. Konstantinov
  • Part IV. Special Cultivation Techniques
  • 15. Disposable Bioreactors for Inoculum Production and Protein Expression / Regine Eibl and Dieter Eibl
  • 16. Hollow Fiber Cell Culture / John M. Davis
  • 17. Cultivation of Mammalian Cells in Fixed-Bed Reactors / Ralf Portner and Oscar B. J. Platas Barradas
  • 18. Configuration of Bioreactors / Dirk E. Martens and Evert Jan van den End
  • Part V. Downstream Techniques
  • 19. Membrane Filtration in Animal Cell Culture / Peter Czermak, Dirk Nehring and Ranil Wickramasinghe
  • 20. Chromatographic Techniques in the Downstream Processing of (Recombinant) Proteins / Ruth Freitag
  • Part VI. Special Applications
  • 21. Vaccine Production: State of The Art and Future Needs in Upstream Processing / Yvonne Genzel and Udo Reichl
  • 22. Retrovirus Production and Characterization / Pedro E. Cruz, Marlene Carmo, Teresa Rodrigues and Paula Alves
  • 23. Insect Cell Cultivation and Generation of Recombinant Baculovirus Particles for Recombinant Protein Production / Sabine Geisse.