Search Results - Pip Pyle~

Google pips Apple in bran survey

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Synergy of ruthenium metallo-intercalator, [Ru(dppz)2(PIP)]2+, with PARP inhibitor Olaparib in non-small cell lung cancer cells by Yusoh, Nur Aininie, Chia, Suet Lin, Saad, Norazalina, Ahmad, Haslina, Gill, Martin R.

“…Poly(ADP-ribose) polymerase (PARP) are critical DNA repair enzymes that are activated as part of the DNA damage response (DDR). …”
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Ambulatory blood pressure monitoring in older people with dementia: a systematic review of tolerability by Conroy, Simon P., Harrison, Jennifer K., van der Wardt, Veronika, Harwood, Rowan H., Logan, Pip, Welsh, Tomas, Gladman, John R.F.

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PARP inhibitor combinations with Olaparib for synergistic efficacy in Olaparib-resistant triple-negative breast cancer cells by Yusoh, Nur Aininie

“…Additionally, co-treatment with the synergistic pairing of Olaparib and Ru-PIP, a ruthenium compound, in non-small cell lung cancer (NSCLC) cells showed enhanced (P < 0.05) DNA damages and reactive oxygen species (ROS) levels, and was able to inhibit the lung cancer spheroids growth, providing further affirmation of expanding the benefits of these identified combinations to other cancer types beyond TNBC. …”
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Synthesis and optimization of mesoporous silica nanoparticles for ruthenium polypyridyl drug delivery by Harun, Siti Norain, Ahmad, Haslina, Lim, Hong Ngee, Chia, Suet Lin, Gill, Martin R.

“…While treatment of Ru-PIP alone is moderately cytotoxic, encapsulated Ru-PIP exerted significant cytotoxicity upon all the cell lines, with half maximal inhibitory concentration (IC50) values determined by MTT (([3-(4,5-dimethylthiazol-2-yl)-2,5-dephenyltetrazolium bromide]) assay at 48 h exposure substantially decreasing from >30 µM to <10 µM as a result of MSN encapsulation. …”
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Engineering of osteogenic construct using rat bone marrow stromal-derived osteoblasts seeded on poly(caprolactone-trifumarate)scaffold / Chai Yoke Chin by Chai, Yoke Chin

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The limits and potential of paleogenomic techniques for reconstructing grapevine domestication by Wales, N., Madrigal, J., Cappellini, E., Baez, A., Castruita, J., Romero-Navarro, A., Caroe, C., Avila-Arcos, M., Penaloza, F., Moreno-Mayar, V., Gasparyan, B., Zardaryan, D., Bagoyan, T., Smith, A., Pinhasi, R., Bosi, G., Fiorentino, G., Grasso, A., Celant, A., Bar-Oz, G., Tepper, Y., Hall, A., Scalabrin, S., Miculan, M., Morgante, M., di Gaspero, G., Gilbert, Thomas

“…Nonetheless, we were able to assign archaeological specimens in the Italian peninsula, Sardinia, UK, and Armenia from pre-Roman to medieval times as belonging to all three major chlorotypes A, C, and D found in modern varieties of Western Europe. …”
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