Search Results - "transcriptional control"

Post-transcriptional control of tumor cell autonomous metastatic potential by the CCR4-NOT deadenylase CNOT7 by Faraji, Farhoud, Hu, Ying, Yang, Howard H., Lee, Maxwell P., Winkler, G. Sebastiaan, Hafner, Markus, Hunter, Kent W.

“…Deadenylation is a general regulatory node for post-transcriptional control by microRNAs and other determinants of RNA stability. …”
Get full text

The ResD Response Regulator, through Functional Interaction with NsrR and Fur, Plays Three Distinct Roles in Bacillus subtilis Transcriptional Control by Henares, Bernadette, Kommineni, S., Chumsakul, O., Ogasawara, N., Ishikawa, S., Nakano, M.

Get full text

Hepatic expression of the tumor necrosis factor family member lymphotoxin-beta is regulated by interleukin (IL)-6 and IL-1beta: Transcriptional control mechanisms in oval cells and hepatoma cell lines by Subrata, L., Lowes, K., Olynyk, John, Yeoh, G., Quail, E., Abraham, L.

Get full text

The oxysterol-binding protein superfamily: New concepts and old proteins by Villasmil, M., Bankaitis, V., Mousley, Carl

“…Kes1 utilizes its dual lipid-binding activities to integrate endosomal lipid metabolism with TORC1 (target of rapamycin complex 1)-dependent proliferative pathways and transcriptional control of nutrient signalling. ©The Authors Journal compilation ©2012 Biochemical Society.…”
Get full text

Effects of CpG islands DNA methylation on the human choline kinase alpha promoter activity by Sa'dom, Siti Aisyah Faten Mohamed

“…In conclusion, this study provides a perspective on the involvement of CpG island and DNA methylation in the transcriptional control of cka gene.…”
Get full text
Get full text

Isolation, characterisation and development of genetic tools for methane-oxidising bacteria by Rumah, Bashir Lawal

“…Gene knockout was achieved in Isolate 12 and M. parvus (OBBP) when DNA ligase IV gene (ligD) was targeted using a plasmid with guide RNA under the transcriptional control of a promoter with moderate strength and Streptococcus pyogenes Cas9 under the transcriptional control of a weak promoter. …”
Get full text

ZBTB48 is both a vertebrate telomere-binding protein and a transcriptional activator by Jahn, A., Rane, G., Paszkowski-Rogacz, M., Sayols, S., Bluhm, A., Han, C., Draškovic, I., Londoño-Vallejo, J., Kumar, Alan Prem, Buchholz, F., Butter, F., Kappei, D.

“…This discovery places ZBTB48 at the interface of telomere length regulation, transcriptional control and mitochondrial metabolism.…”
Get full text

The zinc finger transcription factor RP58 negatively regulates Rnd2 for the control of neuronal migration during cerebral cortical development by Heng, Julian, Qu, Z., Ohtaka-Maruyama, C., Okado, H., Kasai, M., Castro, D., Guillemot, F., Tan, S.

“…Taken together, these studies demonstrate that RP58 is a key player in the transcriptional control of cell migration in the developing cerebral cortex.…”
Get full text

Osteogenic programming of human mesenchymal stem cells with highly efficient intracellular delivery of RUNX2 by Thiagarajan, Lalitha, Abu-Awwad, Hosam Al-Deen M., Dixon, James E.

“…The high transduction efficiency of GET system holds great promise for stem cell therapies by allowing reproducible transcriptional control in stem cells, potentially bypassing problems observed with high-concentration growth-factor or pleiotropic steroid therapies.…”
Get full text

Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS by Majsec, Kristina, Bolt, Edward L., Ivančić-Baće, Ivana

“…Significantly, we describe the new identification that cas3 is also under transcriptional control by H-NS but that this is exerted only in stationary phase cells. …”
Get full text

A novel member of the let-7 microRNA family is associated with developmental transitions in filarial nematode parasites by Winter, Alan D., Gillan, Victoria, Maitland, Kirsty, Emes, Richard D., Roberts, BBrett, McCormack, Gillian, Weir, William, Prostaio, Anna V., Holroyd, Nancy, Berriman, Matthew, Britton, Collette, Devaney, Eileen

“…This study is the first to identify parasitic nematode mRNAs that are verified targets of specific microRNAs and demonstrates that post-transcriptional control of gene expression via stage-specific expression of microRNAs may be important in the success of filarial infection.…”
Get full text

Gene expression and promoter characterisation of stearoyl-ACP desaturase and acyl carrier protein genes from oil palm (Elaeis guineensis jacq.) fruits by Othman, Ashida

“…Using these two genes as models, a better insight on the transcriptional control of fatty-acid biosynthetic genes during period of oil synthesis in oil palm fruits has been achieved in this study.…”
Get full text
Get full text

Study of Rsm/Gac post-transcriptional regulation by quorum sensing, extracellular and intracellular signals in Pseugomonas aeruginosa by Righetti, Karima Maria

“…Since the discovery of QS, there have been many studies showing the importance of this type of regulatory mechanism in the global transcriptional control of gene expression. However, there has been no clear evidence to attribute to QS a key role in post-transcriptional regulation of terminal gene targets. …”
Get full text

Cloning the enterotoxin gene from Clostridium perfringens type A by Iwanejko, Lesley Ann.

“…The region 5' to the ATG translational start codon contained a Shine-Dalgarno sequence and several sequences with significant homology to the putative transcriptional control regions for the tetanus toxin gene. …”
Get full text

Sp1, Acetylated Histone-3 and p300 Regulate TRAIL Transcription: Mechanisms of PDGF-BB-mediated VSMC Proliferation and Migration by Md Azahri, Nor Saadah, Di Bartolo, Belinda A, Khachigian, Levon M., Kavurma, Mary M.

“…PDGF-BB-inducible VSMC proliferation was completely inhibited in VSMCs isolated from aortas of TRAIL(-/-) mice; whereas inducible migration was blocked compared to control VSMCs. TRAIL transcriptional control mediating this response is not established. …”
Get full text
Get full text
Get full text

Metabolic engineering of Geobacillus thermoglucosidasius for utilisation of biomass and production of 3-hydroxypropoinic acid by Bashir, Zeenat

“…When these gene sets were placed under the transcriptional control of Pldh promoter, and the resultant organisms grown aerobically in shake-flasks with glucose as a sole carbon source, production of 3-HP ranged from 3.0-3.8 mM. …”
Get full text

eIF4A2 is a regulator of hypoxic translation and colorectal tumour cell survival by Bolland, Hannah

“…Furthermore, eIF4A2 was found to be under the transcriptional control of HIF2α at both the RNA and protein level in two colorectal cancer cell lines. eIF4A2 was found to be required for hypoxic colorectal cancer cell survival in both 2D and 3D assays, this effect was found to be tumour specific as no negative effect on cell survival was observed in a normal colon epithelial cell line following eIF4A2 knockdown. …”
Get full text

Arabidopsis MS1 functions as a hub in the transcriptional regulatory network of late tapetum development by YIN, WENZHE

“…Phylogenetic footprinting analysis and molecular promoter dissection was used to investigate the transcriptional control of expression and a distal upstream sequence (−2900 to −2066 bp) was found to be essential for the activation of MS1. …”
Get full text

Investigating the role of Y-box binding protein 1 in medulloblastoma tumour progression and drug resistance by Taylor, Louisa

“…To build a global picture of YB-1 transcriptional control in medulloblastoma, whole transcriptome sequencing of YBX1 knockdown cell lines was employed. …”
Get full text

One-step biotransformation of ferulic acid into biovanillin using recombinant Escherichia coli BL21 (DE3) by Zamzuri, Nur Ain

“…The pRSFDuet-1/ech-fcs ii expression system has been constructed by cloning the full length of fcs and ech under the transcriptional control of T7 promoter of pRSFDuet-1 into an E. coli BL21 (DE3).In comparison to wild type, Pseudomonas sp. …”
Get full text
Get full text