Search Results - "systems biology"

Systems biology meets platelet biology by Berndt, Michael, Andrews, R.

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Infobiotics : computer-aided synthetic systems biology by Blakes, Jonathan

“…Until very recently Systems Biology has, despite its stated goals, been too reductive in terms of the models being constructed and the methods used have been, on the one hand, unsuited for large scale adoption or integration of knowledge across scales, and on the other hand, too fragmented. …”
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Integration strategies and data analysis methods for plant systems biology by Lysenko, Artem

“…Understanding how function relates to multiple layers of inactions between biological entities is one of the key goals of bioinformatics research, in particular in such areas as systems biology. However, the realisation of this objective is hampered by the sheer volume and multi-level heterogeneity of potentially relevant information. …”
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Editorial: contribution of translational animal models to the systems biology of neurodegenerative disorders by Mohamed, Wael Mohamed Yousef, Salama, Mohamed M., El Batsh, Maha M., Goh, Eyleen L.

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Mathematical and physical systems biology: application to pharmacokinetic drug-drug interactions and tumour growth by Cherkaoui Rbati, Mohammed

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Parameter estimation in computational systems biology models: a comparative study of initialization methods in global optimization by Muhammad Akmal, Remli, Nor Syahidatul Nadiah, Ismail, Noor Azida, Sahabudin, Nor Bakiah, Abd Warif

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Pembangunan Web Portal Berasaskan MOODLE Bertajuk ‘Human Digestive System’ Biology Tingkatan Empat by Jonid, Muslim, Tang, Yuh Jye

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Finding off-targets, biological pathways, and target diseases for chymase inhibitors via structure-based systems biology approach by Arooj, Mahreen, Sakkiah, S., Cao, G., Kim, S., Arulalapperumal, V., Lee, K.

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Integration of an in vitro renal cellular set of tools with systems biology modelling to predict the renal contribution to the pharmacokinetics of a drug by Taylor, Patrick

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The dynamic balance of import and export of zinc in Escherichia coli suggests a heterogeneous population response to stress by Takahashi, Hiroki, Oshima, Taku, Hobman, Jon L., Doherty, Neil, Clayton, Selina R., Iqbal, Mudassar, Hill, P.J., Tobe, Toru, Ogasawara, Naotake, Kanaya, Shigehiko, Stekel, Dov J.

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Systemic biology of Geobacillus thermocatenulatus upon thermal stress induced by high temperature / Mohd Nur Fakhruzzaman Noorizhab by Noorizhab, Mohd Nur Fakhruzzaman

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Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes by Solimena, Michele, Schulte, A., Marselli, L., Ehehalt, F., Richter, D., Kleeberg, M., Mziaut, H., Knoch, K., Parnis, J., Bugliani, M., Siddiq, A., Jörns, A., Burdet, F., Liechti, R., Suleiman, M., Margerie, D., Syed, F., Distler, M., Grützmann, R., Petretto, E., Moreno-Moral, A., Wegbrod, C., Sönmez, A., Pfriem, K., Friedrich, A., Meinel, J., Wollheim, C., Baretton, G., Scharfmann, R., Nogoceke, E., Bonifacio, E., Sturm, D., Meyer-Puttlitz, B., Boggi, U., Saeger, H., Filipponi, F., Lesche, M., Meda, P., Dahl, A., Wigger, L., Xenarios, I., Falchi, M., Thorens, B., Weitz, J., Bokvist, K., Lenzen, S., Rutter, G., Froguel, P., von Bülow, M., Ibberson, M., Marchetti, P.

“…Signature genes included TMEM37, which inhibited Ca2+-influx and insulin secretion in beta cells, and ARG2 and PPP1R1A, which promoted insulin secretion. Systems biology approaches identified HNF1A, PDX1 and REST as drivers of gene co-expression modules correlated with impaired insulin secretion or glucose tolerance, and 14 out of 19 differentially expressed type 2 diabetic islet signature genes were enriched in these modules. …”
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Genome-scale metabolic modelling of Clostridium autoethanogenum by Norman, Rupert O.J.

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Theoretical approaches to understanding root vascular patterning: a consensus between recent models by Mellor, Nathan, Adibi, Milad, El-Showk, Sedeer, De Rybel, Bert, King, John, Mähönen, Ari Pekka, Weijers, Dolf, Bishopp, Anthony

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Protein ontology: Vocabulary for protein data by Chang, Elizabeth, Sidhu, Amandeep, Dillon, Tharam S., Sidhu, B.

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Protein Ontology: Semantic Data Integration in Proteomics by Sidhu, Amandeep, Dillon, Tharam S., Chang, Elizabeth, Sidhu, B.

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Creating a protein ontology resource by Chang, Elizabeth, Sidhu, Amandeep, Dillon, Tharam S.

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Research in reproduction: challenges, needs, and opportunities by Ivell, Richard

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IRF7-Associated Immunophenotypes Have Dichotomous Responses to Virus/Allergen Coexposure and OM-85-Induced Reprogramming by de Jong, E., Lauzon-Joset, J.F., Leffler, J., Serralha, M., Larcombe, Alexander, Christophersen, Claus, Holt, P.G., Strickland, D.H., Bosco, A.

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The systemic approach on deterministic view of social change by Shogar, Ibrahim

“…Objective: This paper aims to explore how application of principles of systems biology on social phenomenon can contribute to address the above two problems of change management. …”
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