Search Results - "synaptic plasticity"

Functional consequences of pre- and postsynaptic expression of synaptic plasticity by Costa, Rui Ponte, Mizusaki, Beatriz E.P., Sjöström, P. Jesper, van Rossum, Mark C.W.

Subjects: “…synaptic plasticity…”
Get full text

Soft-bound synaptic plasticity increases storage capacity by van Rossum, Mark C.W., Shippi, Maria, Barrett, Adam B.

“…Accurate models of synaptic plasticity are essential to understand the adaptive properties of the nervous system and for realistic models of learning and memory. …”
Get full text

Probabilistic inference of short-term synaptic plasticity in neocortical microcircuits by Costa, Rui P., Sjöström, P. Jesper, van Rossum, Mark C.W.

Subjects: “…short-term synaptic plasticity…”
Get full text

Energy efficient sparse connectivity from imbalanced synaptic plasticity rules by Sacramento, João, Wichert, Andreas, van Rossum, Mark C.W.

“…It is therefore likely that the formation of sparse codes and sparse connectivity are fundamental objectives of synaptic plasticity. In this work we study how sparse connectivity can result from a synaptic learning rule of excitatory synapses. …”
Get full text

Dendritic spine dynamics regulate the long-term stability of synaptic plasticity by O'Donnell, Cian, Nolan, Matthew F., van Rossum, Mark C.W.

“…Long-term synaptic plasticity requires postsynaptic influx of Ca²⁺ and is accompanied by changes in dendritic spine size. …”
Get full text

The Role Of Vacuole Membrane Protein-1 In Neural Calcium Homeostasis And Synaptic Plasticity by Wang, Mengmeng

“…Disruption of the intracellular calcium (Ca2+) dynamics is previously known to affect synaptic plasticity and cognitive function. To date, the effects of vacuole membrane protein 1 (VMP1) on neuronal intracellular calcium homeostasis, synaptic plasticity, and cognitive function remain unexplored. …”
Get full text
Get full text

Modulation Of Dopaminergic System By Mitragynine And The Underlying Mechanisms Instigating Impairment Of Hippocampal Synaptic Plasticity by Salim, Mohamad Azmeer Effendy Md

“…Moreover, mitragynine causes cognitive deficit and impairs the hippocampal synaptic plasticity, but the underlying mechanisms are still unknown. …”
Get full text
Get full text

A low-power memristor based on 2H–MoTe2 nanosheets with synaptic plasticity and arithmetic functions by Yu, T., Zhao, Z., Jiang, H., Weng, Z., Fang, Y., Liu, C., Lei, W., Shafe, S.B., Mohtar, M.N.

Get full text

Energy dependent reinforcement learning based on the neuronal mechanisms of the olfactory processing in mushroom body by Jiang, Jiamu

Subjects: Get full text

Studies Of Clitoria Ternatea Linn. Root Extract On Behavioural Effects And In Vivo Hippocampal Synaptic Plasticity In A Rat Model Of Chronic Cerebral Hypoperfusion by Damodaran, Thenmoly K

“…However, its contribution towards learning and memory enhancement together with in vivo synaptic plasticity in a chronic cerebral hypoperfusion (CCH) rat model has yet to be explored. …”
Get full text
Get full text

Role of presynaptic glutamate receptors in Modulation of long term synaptic plasticity (LTP) in inhibitory synapes of visual pyramidal neuron after epilepsy: a whole cell patch clamp recording by Reza, Mohammed Faruque

Get full text
Get full text

The influence of N6-methyladenosine (m6A) RNA methylation on synaptic function and local protein synthesis by Martinez De La Cruz, Braulio

Subjects: “…m6A RNA epigenetics modifications synaptic plasticity dementia mild cognitive impairment parkinson's disease lewy body dementia pediatric cance glioblastoma ependymoma dendrites dendritic spines translation local protein synthesis neurons human…”
Get full text

Impact of psychological stress and mammary tumour growth on structural and functional protein expression in cognitive brain areas by Alzboon, Walla'

“…Results: Our results suggest that tumour growth itself and psychological stress affected the synaptic plasticity and myelin-related proteins, and consequently, cognitive functions such as learning, memory, and executive functions might be affected. …”
Get full text

The Potential Role of Nicotine in the Treatment of Learning and Memory Impairment after REM Sleep Deprivation by Long, Idris, Abd Rashid, Norlinda

“…It can also disturb synaptic plasticity that can lead to learning and memory impairment. …”
Get full text
Get full text

Unified pre- and postsynaptic long-term plasticity enables reliable and flexible learning by Costa, Rui Ponte, Froemke, Robert C., Sjöström, P. Jesper, van Rossum, Mark C.W.

“…Although it is well known that long-term synaptic plasticity can be expressed both pre- and postsynaptically, the functional consequences of this arrangement have remained elusive. …”
Get full text

Step-by-step approach: stereotaxic surgery for in vivo extracellular field potential recording at the rat Schaffer collateral-CA1 synapse using the eLab system by Azimzadeh, Mansour, Mohd Azmi, Mohd Amirul Najwa, Reisi, Parham, Cheah, Pike-See, Ling, King-Hwa

“…This study presents a practical and functional manual guide for surgical electrode implantation in rodent models using the eLab/ePulse electrophysiology system for recording and stimulation pur- poses to assess neuronal functionality and synaptic plasticity. The evaluation parameters included the input/output function (IO), paired-pulse facilitation or depression (PPF/PPD), long-term po- tentiation (LTP), and long-term depression (LTD).…”
Get full text
Get full text

The effects of long-term saturated fat enriched diets on the brain lipidome by Giles, C., Takechi, Ryu, Mellett, N., Meikle, P., Dhaliwal, S., Mamo, John

“…The brain is highly enriched in lipids, where they influence neurotransmission, synaptic plasticity and inflammation. Non-pathological modulation of the brain lipidome has not been previously reported and few studies have investigated the interplay between plasma lipid homeostasis relative to cerebral lipids. …”
Get full text
Get full text

Specificity factors in cytoplasmic polyadenylation by Charlesworth, Amanda, Meijer, Hedda A., de Moor, Cornelia H.

“…In recent years, however, has been implicated in many other processes, including synaptic plasticity and mitosis. This review aims to introduce cytoplasmic polyadenylation with an emphasis on the factors and elements mediating this process for different mRNAs and in different animal species. …”
Get full text

Brain transcriptome perturbations in the Hfe -/- mouse model of genetic iron loading by Johnstone, D., Graham, Ross, Trinder, D., Delima, R., Riveros, C., Olynyk, John, Scott, R., Moscato, P., Milward, E.

“…There were robust changes of at least 2-fold in levels of transcripts for prominent genes relating to transcriptional regulation (FBJ osteosarcoma oncogene Fos, early growth response genes), neurotransmission (glutamate NMDA receptor Grin1, GABA receptor Gabbr1) and synaptic plasticity and memory (calcium/calmodulin-dependent protein kinase IIα Camk2a). …”
Get full text

A biophysical model of dynamic balancing of excitation and inhibition in fast oscillatory large-scale networks by Abeysuriya, Romesh G., Hadida, Jonathan, Sotiropoulos, Stamatios N., Jbabdi, Saad, Becker, Robert, Hunt, Benjamin A.E., Brookes, Matthew J., Woolrich, Mark W.

“…In this study, we simulate a cortical brain network using the Wilson-Cowan neural mass model with conduction delays and noise, and use inhibitory synaptic plasticity (ISP) to dynamically achieve a spatially local balance between excitation and inhibition. …”
Get full text