Search Results - "pharmacodynamics"

Pharmacodynamics for Medical Students by Lim, William/W.K.

“…A video primer on pharmacodynamics to enable medical students to understand the basic terminology and be able to interpret receptor binding and dose response...…”
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Pharmacodynamics and pharmacokinetics of phenylbutazone in calves by A.K., Arifah, Lees, P.

“…Phenylbutazone (PBZ) was administered to six calves intravenously (i.v.) and orally at a dose rate of 4.4 mg/kg in a three-period cross-over study incorporating a placebo treatment to establish its pharmacokinetic and pharmacodynamic properties. Extravascular distribution was determined by measuring penetration into tissue chamber fluid in the absence of stimulation (transudate) and after stimulation of chamber tissue with the mild irritant carrageenan (exudate). …”
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Ketoprofen in the Cat: Pharmacodynamics and Chiral Pharmacokinetics by Lees, Peter, Taylor, Polly Monroe, Landoni, Maria Fabiana, Abdul Kadir, Arifah, Waters, C.

“…The non-steroidal anti-inflammatory drug ketoprofen (KTP) was administered as the racemate to cats intravenously (IV) and orally at clinically recommended dose rates of 2 and 1 mg/kg, respectively, to establish its chiral pharmacokinetic and pharmacodynamic properties. After IV dosing, clearance was more than five times greater and elimination half-life and mean residence time were approximately three times shorter for R(−) KTP than for S(+) KTP. …”
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Pharmacodynamics of colistin against Acinetobacter baumannii by Mohd Rasidin, Rashizal Sazli

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Pharmacodynamics and pharmacokinetics of ketoprofen enantiomers in sheep by Arifah, Abdul K., Landoni, Maria F., Frean, Stephen P., Lees, Peter

“…Objective - To establish pharmacokinetic and pharmacodynamic properties of a racemic mixture and individual R(-) and S(+) enantiomeric forms of ketoprofen (KTP) in sheep and determine pharmacodynamic variables of KTP by pharmacokinetic-pharmacodynamic modeling. …”
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Development of a Pharmacodynamic Model of Murine Malaria by Gibbons, Peter Luke

“…The rational design of antimalarial therapies has historically been compromised by a paucity of pharmacodynamic data contributing to resistance through deployment of suboptimal doses. …”
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Pharmacodynamics of doxycycline in a murine malaria model by Batty, Kevin, Law, Angela, Stirling, V., Moore, Brioni

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Pharmacokinetic And Pharmacodynamic Modeling Of Mitragynine In PainTolerance by Ramachandram, Dinesh Sangarran

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Clinical pharmacokinetics and pharmacodynamics of mycophenolate in patients with autoimmune disease by Abd. Rahman, Nurul Azrin, Tett, Susan E., Staatz, Christian E.

“…An understanding of the pharmacokinetics and pharmacodynamics of mycophenolate in this population should assist the clinician with rational dosage decisions. …”
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Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model by Moore, Brioni, Batty, Kevin, Andrzejewski, C., Jago, Jeffrey, Page-Sharp, M., Ilett, K.

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Pharmacodynamic studies of antimalarial drugs in a murine malaria model by Moore, Brioni R.

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Piperaquine pharmacodynamics and parasite viability in a murine malaria model by Moore, Broni, Ilett, K. F., Page-Sharp, Madhu, Jago, Jeffrey, Batty, Kevin

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Pharmacodynamics, chiral pharmacokinetics and PK–PD modelling of ketoprofen in the goat by Abdul Kadir, Arifah, Landoni, Maria Fabiana, Lees, Peter

“…The pharmacokinetics and pharmacodynamics of KTP were investigated using a tissue cage model of acute inflammation. …”
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Pharmacodynamics, chiral pharmacokinetics and PK-PD modelling of ketoprofen in the goat by A. K., Arifah, M. F., Landoni, P., Lees

“…The pharmacokinetics and pharmacodynamics of KTP were investigated using a tissue cage model of acute inflammation. …”
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Mechanism-based model of parasite growth and dihydroartemisinin pharmacodynamics in murine malaria by Patel, K., Batty, Kevin, Moore, Brioni, Gibbons, P., Bulitta, J., Kirkpatrick, C.

“…Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) models for antimalarials are scarce, despite their potential to optimize antimalarial combination therapy. …”
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Pharmacokinetics, Pharmacodynamics and Allometric Scaling of Chloroquine in a Murine Malaria Model by Moore, Brioni, Page-Sharp, Madhu, Stoney, Jillian, Ilett, K., Jago, Jeffrey, Batty, Kevin

“…The single-dose pharmacodynamic study (10 to 50 mg CQ/kg of body weight) showed dose-related reduction in parasitemia (5- to >500-fold) and a nadir 2 days after the dose. …”
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Development of a pharmacodynamic model of murine malaria and antimalarial treatment with dihydroartemisinin by Gibbons, Peter, Batty, Kevin, Barrett, P., Davis, Timothy, Ilett, Kenneth

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Pharmacokinetic and pharmacodynamic features of nanoemulsion following oral, intravenous, topical and nasal route by Chowdhury, Hira, Gorain, Bapi, Chatterjee, Bappaditya, Mandal, Uttam Kumar, Sengupta, Pinaki, Tekade, Rakesh

“…Keywords: Hydrophobicity, oral delivery, pharmacokinetics, pharmacodynamics, routes of administration.…”
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Developing and validating a new comprehensive glucose-insulin pharmacokinetics and pharmacodynamics model by Ummu Kulthum, Jamaludin

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Applying pharmacokinetic/pharmacodynamic principles in critically ill patients: optimizing efficacy and reducing resistance development by Abdul Aziz, Mohd. Hafiz, Lipman, Jeffrey, Mouton, Johan W., Hope, William W., Roberts, Jason A.

“…Optimal and timely pharmacokinetic/pharmacodynamic (PK/PD) target attainment has been associated with an increased likelihood of clinical andmicrobiological success in critically ill patients. …”
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