Search Results - "peptides"
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Neuroprotective peptides fused to arginine-rich cell penetrating peptides: Neuroprotective mechanism likely mediated by peptide endocytic properties
Published 2015“…Several recent studies have demonstrated that TAT and other arginine-rich cell penetrating peptides (CPPs) have intrinsic neuroprotective properties in their own right. …”
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Formulation Development and Optimization for Transdermal Delivery of Peptide and Peptide Like Drugs
Published 2018“…This research focused on transdermal penetration enhancement of peptides, peptide-like and lipophilic drugs by employing physical and chemical penetration enhancers. …”
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Peptides for biopharmaceutical applications
Published 2018“…However, the use of techniques such as peptide engineering, peptide conjugation, and formulation strategies to improve parenteral delivery are paving the way for an increased use of peptides as biologics. …”
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The development of novel solid phase methodologies for the synthesis of atypical peptides and non-peptide entities
Published 1996“…Solid phase peptide synthesis (SPPS) of branched/cyclic peptides, multiple antigenic peptides (MAPs), pseudopeptide toxins etc. requires amine protection orthogonal to the established Fmoc/Boc protocols. …”
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Efficacy of antibacterial peptides against peptide-resistant mrsa is restored by permeabilization of bacteria membranes
Published 2016“…Clinical application of antimicrobial peptides (AMPs), as with conventional antibiotics, may be compromised by the development of bacterial resistance. …”
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Nano-encapsulation of proteins and peptides
Published 2017“…Nanoencapsulation of proteins and peptides is an attractive strategy to improve the stability of proteins and peptides and maintain activity at the target site. …”
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Development of peptide vaccines in dengue
Published 2017“…This can be achieved by designing a multi-epitope peptide vaccine comprising B, CD8+ and CD4+ T cell epitopes. …”
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Protein and peptide biopharmaceuticals: An overview
Published 2017“…Bioactive proteins and peptides are recognised as novel therapeutic molecules with varying biological properties for potential medical applications. …”
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Peptide Electrophoretic Patterns of Cucumoviruses
Published 1986“…The peptide electrophoretic patterns of several cucumovirus isolates were compared using 15% polyacrylamide slab-gels. …”
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Polyoxometalates and peptides: hybridisation and disulfide detection
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Enterovirus specific anti-peptide antibodies
Published 2015“…This review describes the production of cross-neutralizing anti-peptide antibodies in response to immunization with synthetic peptides selected from in silico analysis, generation of B-cell epitopes of EV71 conjugated to a promiscuous T-cell epitope from Poliovirus, and evaluation of the neutralizing activities of the anti-peptide antibodies. …”
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Peptides as therapeutic agents for dengue virus
Published 2017“…In this review, the design of peptide drugs, antiviral activities and mechanisms of peptides and peptidomimetics (modified peptides) action against dengue virus are discussed. …”
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Antiviral peptides against dengue virus
Published 2022“…Technological advancements in recent years have paved the way towards initiating an interest in the development of peptide drugs by the pharmaceutical industry. This chapter highlights the current status of the development of antiviral peptides targeting DENV, strategies that were utilized to design antiviral peptides, interactions that were identified between antiviral peptides and DENV host cell receptors or enzymes, advantages and disadvantages of antiviral peptides, as well as potential ways to overcome their limitations.…”
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Process Development for Bioactive Peptide Production
Published 2017“…At this production level and at a peptide market value of USD 88.5/g peptide, the annual expected value of peptide will be USD 41,858,307,460. …”
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Non-canonical peptides bound to MHC
Published 2009“…To design effective peptide based vaccines a comprehensive understanding of the specific interactions between MHC molecules and peptide, and of TCR recognition of MHC/peptide is valuable. …”
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Vesicles for transdermal delivery of peptides and proteins
Published 2016“…They have been investigated as drug carriers for a range of small molecules, peptides, proteins and vaccines, both in vitro and in vivo. …”
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