Search Results - "palmitoylation"

Synthesis and optimization of palmitoyl-chitosan nanoparticles as a potent dual antioxidant carrier with hydrophobic and hydrophilic compounds by Othman, Nurhanisah

“…Thus, palmitic acid was conjugated on the CS through hydrophobic modification, which produced palmitoyl-chitosan nanoparticles (PCNP). The amphiphilic PCNP encapsulated with TQ and LAA showed increased size, 247.7 ± 24.0 nm and PDI, 0.35 ± 0.04. …”
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l-ascorbic acid and thymoquinone dual-loaded palmitoyl-chitosan nanoparticles: improved preparation method, encapsulation and release efficiency by Othman, Nurhanisah, Md. Jamil, Siti Nurul Ain, Masarudin, Mas Jaffri, Abdullah, Luqman Chuah, Daik, Rusli, Sarman, Nor Syazwani

“…Therefore, hydrophobic modification on chitosan with palmitic acid was conducted in this study to provide an amphiphilic environment for better encapsulation of antioxidants; hydrophobic thymoquinone (TQ) and hydrophilic l-ascorbic acid (LAA). Palmitoyl chitosan nanoparticles (PCNPs) co-loaded with TQ and LAA (PCNP-TQ-LAA) were synthesized via the ionic gelation method. …”
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Enzymatic interesterification, fractional crystallisation and its physicochemical properties of palm-based cocoa butter equivalent with high palmitoyl-oleoyl-stereoyl level by Mohamad Alwi, Siti Maslina

“…Fully hydrogenated fat with low Iodine Value used as the stearic donor to obtain high levels of POS (1-palmitoyl-2-oleoyl-3-stearoyl-sn-glycerol) triacylglycerols. …”
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Increased radical scavenging activity of thymoquinone and L-ascorbic acid dual encapsulated in palmitoyl-chitosan nanoparticles in a human normal lung fibroblast, MRC-5 due to synergistic antioxidative effects by Othman, Nurhanisah, Md. Jamil, Siti Nurul Ain, Masarudin, Mas Jaffri, Mohd Jusoh, Ruqayyah Ainul Bashirah, Alamassi, Mohammed Numan

“…Generally, NPs carry only one active ingredient; this study, however, utilized chitosan nanoparticles (CNPs) and hydrophobically modified palmitoyl-chitosan nanoparticles (PCNPs) that were dual encapsulated with antioxidants of different polarities, namely, hydrophobic thymoquinone (TQ) and hydrophilic L-ascorbic acid (LAA) to evaluate their combination effects in scavenging free radicals. …”
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Hydrophobically Modified Pegylated Chitosan Derivative: Synthesis, Characterisation And Formulation Of Nanoparticles by Chong, Wai Mun

“…PGC-PEG was synthesised in a stepwise manner involving acid degradation, PEGylation and palmitoylation. The characterisation of several batches of PGC-PEG revealed polymer with 3.3% PEGylation and 59% palmitoylation with critical micelle concentration (CMC) value of 0.063 mg/mL as suitable to be incorporated with ITZ. …”
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Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells by Schwab, R., Amin, N., Flanagan, D., Johanson, T., Phesse, T., Vincan, Elizabeth

“…Results: Wnt secretion is dependent on palmitoylation by Porcupine (PORC). A PORC inhibitor (IWP2) that prevents Wnt secretion, blocked the epithelial transition of mesenchymal LIM1863-Mph cells. …”
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Phagocyte-like NADPH oxidase (Nox2) promotes activation of p38MAPK in pancreatic ß-cells under glucotoxic conditions: Evidence for a requisite role of Ras-related C3 botulinum toxi... by Sidarala, V., Veluthakal, R., Syeda, K., Vlaar, C., Newsholme, Philip, Kowluru, A.

“…We report a significant inhibition of p38MAPK phosphorylation by Rac1 inhibitors, implying a regulatory role for Rac1 in promoting the Nox2-p38MAPK signaling axis in the ß-cell under the duress of HG. 2-Bromopalmitate, a known inhibitor of protein (Rac1) palmitoylation, significantly reduced HG-induced p38MAPK phosphorylation. …”
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Synthesis and characterization of novel palmitic acid conjugated tetrapeptide as a new active molecule for wound treatment by Md Fadilah, Nur Izzah

“…From the results, it was evident that Palmitoyl-GDPH gave higher percentage activity of collagen enzyme (80.00 ± 2.22%). …”
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Neutral lipid profile of sago worm, the larva of weevil rynchophorus ferrugineus by Mohd. Ali, Ozair, Chu, K. L., Wang, C. W.

“…Other minor triacylglycerols identified in the neutral lipid of fat tissue from viscera were l-palmitoyl-2-oleoyl-3-linolenoyl-rac-glycerol, POLn (0.6%), 1- palmitoyl-2-linoleoyl-3-linoleoyl-rac-glycerol, PLL (0.1%), l-palmitoyl-2-palmitoyl-3- linoleoyl-rac-glycerol, PPL(1.1%) and l-palmitoyl-2-stearoyl-3-linoleoyl-rac-glycerol, PSO (2.9%) whereas that of cuticle were POLn (0.2%), PLL (1.0%), PPL(1.1%) and PSO (2.9%).…”
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Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery by Ichimizu, S., Watanabe, H., Maeda, H., Hamasaki, K., Nakamura, Y., Chuang, Victor, Kinoshita, R., Nishida, K., Tanaka, R., Enoki, Y., Ishima, Y., Kuniyasu, A., Kobashigawa, Y., Morioka, H., Futaki, S., Otagiri, M., Maruyama, T.

“…The palmitoyl CPPs forms a stable complex with HSA by anchoring itself to the high affinity palmitate binding sites of HSA. …”
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Forensic feed strategy: incorporation of multivariate and instrumental analyses for authentication of fish feed sources by Idris, Mohamed Haniff Hanafy, Abdullah Sani, Muhamad Shirwan, Mohd Hashim, Amalia, Mohd Zaki, Nor Nadiha, Abdul Manaf, Yanty Noorzianna, Mohd Desa, Mohd Nasir, Arshad, Syariena, Yuswan, Mohd Hafis, Hassan, Mohd Sukri, Yusof, Yus Aniza, Kamaruddin, Mohd Salleh, Mustafa, Shuhaimi

“…At cumulative variability (90.625%) and Keiser-Meyer Olkin (KMO) value (0.811), the PCA identified 10 TAGs and 3 TPs with strong factor loading. The dioleoyl-1-palmitoyl glycerol (POO), dipalmitoyl-3-oleoyl glycerol (PPO) and dipalmitoyl-1-linoleoyl (PPL) characterized fish feeds containing palm oil while dilinoleoyl-1-oleoyl glycerol (OLL), dilinoleoyl-1-palmitoyl (PLL), dioleoyl-3-linoleoyl glycerol (OOL), initial cooling temperature (ICT), palmitoyl-oleoyl-linoleoyl glycerol (POL), palmitoyl-stearoyl-oleoyl glycerol (PSO) and final heating temperature (FHT) characterized lard-containing fish feeds. …”
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Similar physical characteristics but distinguishable sn-2 palmitic acid content and reduced solid fat content of chemically interesterified palm olein compared with native palm ole... by Mo, Shuen Yeing, Teng, Kim Tiu, Nesaretnam, Kalanithi, Lai, Oi Ming

“…The CIEPO olein fraction has a reduced SFC at 37°C from 8.6 to 4.2%, overall decreased SFC, slip melting point (SMP) at 33°C, a reduced palmitoyl-palmitoyl-palmitoyl (PPP) from 6.0 to 3.7 mol% and lower heating peaks in thermal profile compared with the untreated CIEPO. …”
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Enzymatic Interesterification of Palmolein with Stearic Acid by Using Immobilized Pseudomonaslipase by Yassin, Atif Abd Elmoneim Ahmed

“…It also resulted in a decrease in the concentrations of the four main triglycerides in palm olein namely I-palmitoyl-dioleoyl glycerol (POO), 1,3-dipalmitoyl-2-oleoyl glycerol (POP), 1-palmitoyl-2-oleoyl-linoleoyl glycerol (POL) and 1,3-dipalmitoyl-2-linoleoyl glycerol (PLP). …”
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Differentiation of pork from other meat species by lipid analysis methodologies by Marikkar, Mohammed Nazrim

“…Because of this, some peak ratios based on stearoyl-palmitoyl-oleoyl glycerol (SPO), linoleoyl-palmitoyl-oleoyl glycerol (LPO) and dioleoyl-palmitoyl glycerol (OPO) were found to be useful parameters to differentiate lard from other meat species. …”
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Specific heat capacity of pure triglycerides by differential scanning calorimeter by Morad, Noor Azian, Abu Hasan, Adilah

“…The mixed triglycerides used are 1,2-dimyristoyl-3-oleoyl, 1,2-dimyristol-3-palmitoyl and 1,2- dioleoyl-3-palmitoyl. Comparisons of the specific heat capacity results are made with the reported values and values calculated for triglycerides using estimation methods. …”
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Comparison of subcritical CO2 and ultrasound-assisted aqueous methods with the conventional solvent method in the extraction of avocado oil by Tan, Chin Xuan, Chong, Gun Hean, Hamzah, Hazilawati, Mohd Ghazali, Hasanah

“…Regardless of the extraction methods, the major fatty acids in avocado oils were oleic (40.73-42.72%) and palmitic (28.12-34.48%) acids whereas the major triacylglycerols in avocado oils were palmitoyl-dioleoyl-glycerol (POO; 22.48-23.01%) and palmitoyl-oleoyl-linoleoyl-glycerol (POL; 17.64-18.23%). …”
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Differentiation of pork from other meat species by lipid analysis methodologies by Marikkar, Jalaldeen Mohamed Nazrim, Ahmad Nizar, Nina Naquiah

“…Because of this, some peak ratios based on stearoyl-palmitoyl-oleoyl 'glycerol (Spa), linoleoyl-palmitoyl-oleoyl glycerol (LPO) and dioleoyl-palmitoyl glycerol (OPO) were found to be useful parameters to differentiate lard from other meat species. …”
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Composition and thermal analysis of lard stearin and lard olein by Yanty, N.A.M., Marikkar, Mohammed Nazrim, Che Man, Y.B., Long , Kamariah

“…Similar to native lard, both LS and LO contained approximately equal proportions of TAG molecules namely, linoleoyl-palmitoyl-oleoyl glycerol (LPO) and dioleoyl-palmitoyl glycerol (OPO). …”
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Composition and thermal analysis of lard stearin and lard olein by Abdul Manaf, Yanty Noorzianna, Marikkar, Jalaldeen Mohammed Nazrim, Che Man, Yaakob, Long, Kamariah

“…Similar to native lard, both LS and LO contained approximately equal proportions of TAG molecules namely, linoleoyl-palmitoyl-oleoyl glycerol (LPO) and dioleoyl-palmitoyl glycerol (OPO). …”
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Stimulation of calcium efflux from rat liver mitochondria by adenosine 3′5′ cyclic monophosphate by Arshad, Juzu Hayati, Holdsworth, Eric S.

“…It was found that using palmitoyl coenzyme A together with carnitine and ATP as substrates that Ca2+ was released gradually from mitochondria by adenosine 3'5' cyclic monophosphate. …”
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