Search Results - "optogenetics"

Development and characterisation of optogenetic tools for non-invasive control of cellular functions in epithelia by Ciampani, Victoria

Subjects: “…Epithelial cells; Epithelia; optogenetic tools…”
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Behavioral flexibility is increased by optogenetic inhibition of neurons in the nucleus accumbens shell during specific time segments by Aquili, Luca *, Liu, Andrew W., Shindou, Mayumi, Shindou, Tomomi, Wickens, Jeffrey R.

“…To investigate the role of nucleus accumbens neural activity in behavioral flexibility, we used light-activated halorhodopsin to inhibit nucleus accumbens shell neurons during specific time segments of a bar-pressing task requiring a win–stay /lose–shift strategy. We found that optogenetic inhibition during action selection in the time segment preceding a lever press had no effect on performance. …”
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The causal role between phasic midbrain dopamine signals and learning by Aquili, Luca *

“…The article discusses how phasic dopamine (DA) may relate to action selection, goal-directed behavior, and behavioral flexibility of a mice. It states that optogenetic targeting of midbrain DA cells and striatal projections showed role in reward prediction and behavioral flexibility. …”
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Feedback inhibition enables theta-nested gamma oscillations and grid firing fields by Pastoll, Hugh, Solanka, Lukas, van Rossum, Mark C.W., Nolan, Matthew F.

“…Cortical circuits are thought to multiplex firing rate codes with temporal codes that rely on oscillatory network activity, but the circuit mechanisms that combine these coding schemes are unclear. We establish with optogenetic activation of layer II of the medial entorhinal cortex that theta frequency drive to this circuit is sufficient to generate nested gamma frequency oscillations in synaptic activity. …”
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