Search Results - "nucleosome"

Genome-wide nucleosome map and cytosine methylation levels of an ancient human genome by Pedersen, J., Valen, E., Velazquez, A., Parker, B., Rasmussen, M., Lindgreen, S., Lilje, B., Tobin, D., Kelly, T., Vang, S., Andersson, R., Jones, P., Hoover, C., Tikhonov, A., Prokhortchouk, E., Rubin, E., Sandelin, A., Gilbert, Thomas, Krogh, A., Willerslev, E., Orlando, L.

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Anti-nucleosome antibodies as a disease activity marker in patients with systematic lupus erythematosus by Ha, Suliman Tayseer

“…The specificity of anti-nucleosome and anti-dsDNA antibodies was 98% and 97% respectively. …”
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Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment by Habib, Omar, M. Sakri, Rozita, Ghazalli, Nadiah, Chau, De Ming, Ling, King Hwa, Abdullah, Syahril

“…Our findings suggest that nucleosome enrichment could regulate non-integrating CpG-free pDNA expression and has implications on pDNA design.…”
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Identification of the ISWI chromatin remodeling complex of the early branching Eukaryote Trypanosoma brucei by Stanne, Tara, Shankar Narayanan, Mani, Ridewood, Sophie, Ling, Alexandra, Witmer, Kathrin, Kushwaha, Manish, Wiesler, Simone, Wickstead, Bill, Wood, Jennifer, Rudenko, Gloria

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Transcriptional regulation and responses in filamentous fungi exposed to lignocellulose by Daly, Paul, van Munster, Jolanda M., Archer, David B., Raulo, Roxane

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Regulation of genes encoding enzymes involved in plant cell wall deconstruction in Trichoderma reesei by Ries, Laure Nicolas Annick

“…Furthermore, CRE1 was also shown to be important for nucleosome positioning within the cbh1 coding region under repressing conditions and proposed to do so by interaction with (a) yet unidentified protein(s).…”
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Role of RNF20 in cancer development and progression – a comprehensive review by Sethi, G., Shanmugam, M., Arfuso, Frank, Kumar, Alan Prem

“…In this review, we summarized the current knowledge of RNF20 in chronic inflammation-driven cancers, DNA DSBs, and apoptosis, and its impact on chromatin structure beyond the single nucleosome level.…”
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Cloning and expression of truncated CTCF by Ngan, Chot San

“…Among them are proteins involved in transcriptional and cell proliferation control, RNA processing, signal transduction, nucleosome components and tumor suppressors. CTCF consists of N-tenninal domain, zinc finger domain and C-terminal domain. …”
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Cloning and expression of truncated CTCF by Ngan, Chot San

“…Among them are proteins involved in transcriptional and cell proliferation control, RNA processing, signal transduction, nucleosome components and tumor suppressors. CTCF consists of N-terminal domain, zmc finger domain and C-terminal domain. …”
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Regulation of human heterochromatin protein 1 binding protein 3 (HP1BP3, also known as HP1BP74) in response to the DNA damage by Normatova, Makhliyo

“…DNA repair involves both post-translational modification of nucleosomes and concentration of DNA repair proteins at the damaged site(s). …”
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Jerantinine A induces tumor-specific cell death through modulation of splicing factor 3b subunit 1 (SF3B1) by Chung, Felicia Fei-Lei, Tan, Perry Faith Tze Ming, Raja, Vijay Joseph, Tan, Boon-Shing, Lim, Kuan-Hon, Kam, Toh-Seok, Hii, Ling-Wei, Tan, Si Hoey, See, Sze-Jia, Tan, Yuen-Fen, Wong, Li-Zhe, Yam, Wai Keat, Mai, Chun Wai, Bradshaw, Tracey D., Leong, Chee-Onn

“…Further analyses showed that JA stabilizes endogenous SF3B1 protein in breast cancer cells and induced dissociation of the protein from the nucleosome complex. Together, these results demonstrate that JA exerts its antitumor activity by targeting SF3B1 and SF3B3 in addition to its reported targeting of tubulin polymerization.…”
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Polyelectrolyte models and molecular dynamics studies of the DNA polymer and DNA-NCP complexes in salt solutions / Ahmad Anggraria Jaya Agung by Ahmad Anggraria Jaya, Agung

“…In a cell, the DNA strand wraps around the so called nucleosome core particle (NCP). In this study, the NCP is represented by a large sphere with radius 35 Å and charge +150. …”
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Application of Proteomics Approaches in the Identification of New Markers and Therapeutic Targets for Breast Cancer by Moh’d Hamadneh, Lama Abdel Qader

“…Tumor rejection antigen (gp96), heat shock protein 90α, nucleosome assembly protein 1-like 1 and opioid-binding cell adhesion molecule precursor were identified and found to be upregulated in breast cancer cell lines when compared to the normal breast cell line. …”
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Heterochromatin protein HP1BP3 modulates haematopoiesis and leukemogenesis by Almars, Amany

“…Moreover, HP1BP3 modulates the entry/exit of nucleosomal DNA by binding to Heterochromatin Protein 1 α (HP1α) and maintains the chromatin integrity during the G1–S phase transition. …”
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Epidemiology of Diseases of Cultured Black Tiger Shrimp (Penaeus Monodon) In Peninsular Malaysia and Experimental Inactivation of White Spot Syndrome Virus by Wang, Yin Geng

“…For most viral infections, histopathological and ultrastructural studies showed detail pathogenesis and cytopathic effects. The nucleosome of WSSV was described for the first time in the penaeid viruses, and the mechanism of white spot formation caused by WSSV was preliminarily elucidated. …”
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Using chromosome engineering on a natural isolate of the fission yeast, Schizosaccharomyces pombe, to investigate the epigenetic inheritance of the kinetochore by Barbosa, Anne Caroline

“…In humans, cytogenetic data suggests that the number of centromere-specific CENP-A nucleosomes at each centromere is approximately uniform regardless of the sequence and length of the centromeric DNA. …”
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Histopathology and cytopathology of white spot syndrome virus (WSSV) in cultured Penaeus monodon from peninsular Malaysia with emphasis on pathogenesis and the mechanism of white s... by Wang, Y.G., Hassan, M.D., Shariff, M., Zamri, S.M., Chen, X.

“…The virions were elliptical to short rods with trilamilar envelopes that measured 305 ± 30 x 127 ± 11 nm. Viral nucleosomes were often present singly in infected nuclei and were associated with the early stages of viral replication. …”
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Oncolysis of breast, liver and leukemia cancer cells using ethyl acetate and methanol extracts of goniothalamus umbrosus. by Abdelwahab, Siddig Ibrahim, Abdul, Ahmad Bustamam, Mohan, Syam Murali, Al-Zubairi, Adel Sharaf, Elhassan Taha, Manal Mohamed

“…DNA laddering assay was performed to assess endo-nucleosomal fragmentation. The MTT assay results revealed that only the ethyl acetate extract has anticancer effects on human breast cancer cells (MCF-7). …”
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Anti-proliferative effect and induction of apoptosis in androgen-independent human prostate cancer cells by 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one by Citalingam, Kamini, Abas, Faridah, Lajis, Nordin H., Othman, Iekhsan, Naidu, Rakesh

“…Highest enrichment of free nucleosomes was noted at 48 h after treatment with MS17. …”
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The curcumin analogue 1,5-bis(2-hydroxyphenyl)-1,4-pentadiene-3-one induces apoptosis and downregulates E6 and E7 oncogene expression in HPV16 and HPV18-infected cervical cancer ce... by Paulraj, Felicia, Abas, Faridah, Lajis, Nordin, Othman, Iekhsan, Syed Hassan, Sharifah, Naidu, Rakesh

“…At 24 h of treatment, fluorescence microscopy detected that MS17-exposed cells exhibited significant morphological changes consistent with apoptosis, corroborated by an increase in nucleosomal enrichment due to DNA fragmentation in HeLa and CaSki cells and activation of caspase-3 activity in CaSki cells. …”
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