Search Results - "myristoylation"

Sequence analysis of the ribosomal protein gene, RPS15 in cell line derived from human colorectal carcinoma by Yew, Keh Li

“…In addition, RPS15 gene encodes two biological significant sites, which are protein kinase C phosphorylation and N-myristoylation site. This finding suggests RPS15 gene is highly conserved in HCT116 and encodes for two biological important sites.…”
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Sequence analysis of ribosomal protein gene, L14 in human colorectal carcinoma cell line by Najian, binti Ibrahim

“…Besides that, translation result of RPL 14 illustrated that RPL 14 gene encodes a few biologically important sites such as phosphorylations sites for many protein kinases, myristoylation site, and leucine zipper pattern which makes RPL 14 one of the common housekeeping genes in human.…”
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Isolation and Characterization of Avirulence Genes in Magnaporthe oryzae by Mui, Sie Jee, Whye, Leonard Kit Lim, Martina Azelin, anak Dirum, Sara, Ilia, Che, Hashim, Muhammad Shafiq, Masri, Hui, Ying Tan, Lee, San Lai, Kuok, Freddy San Yeo, Hung, Hui Chung

“…Results revealed that all eight Avr genes (including four other global isolates) shared similar N-myristoylation site and a novel motif. 3D modeling revealed similar β-sandwich structure in AvrPiz-t and AVR-Pik despite sequence dissimilarities. …”
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Cloning and characterization of ribulose-1,5-bisphosphate carboxylase/oxygenase small subunit (RbcS) cDNA from green microalga Ankistrodesmus convolutus by Thanh, Tran, Chi, Vu Thi Quynh, Abdullah, Mohd Puad, Omar, Hishamuddin, Noroozi, Mostafa, Napis, Suhaimi

“…The AcRbcS contained a few conserved domains including protein kinase C phosphorylation site, tyrosine kinase phosphorylation site and N-myristoylation sites. The AcRbcS was successfully expressed in Escherichia coli and a ~21 kDa of anticipated protein band was observed on SDS-PAGE. …”
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Organogels for intratumoural delivery by Mohamed, Masar Basim Mohsin

“…Secondly, they were able to slow down the release of N4-myristoyl gemcitabine.…”
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Antiprotozoals based on the inhibition of N-Myristoyltransferase by Clegg, Robert Alexander Norman

“…This initial investigation synthesised a simplified transition state mimetic based from myristic acid and included alkene and phenoxy variation of the myristoyl chain. A series of Inhibitors were developed using a coenzyme-A fragment. …”
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Cudraflavone C induces tumor-specific apoptosis in colorectal cancer cells through inhibition of the phosphoinositide 3-kinase (PI3K)-AKT pathway by Castresana, Javier S., Soo, Hsien-Chuen, Chung, Felicia Fei-Lei, Lim, Kuan-Hon, Yap, Veronica Alicia, Bradshaw, Tracey D., Hii, Ling-Wei, Tan, Si-Hoey, See, Sze-Jia, Tan, Yuen-Fen, Leong, Chee-Onn, Mai, Chun-Wai

“…Cud C also inhibited phosphorylation of AKT independent of NFκB activity in CRC cells, while ectopic expression of myristoylated AKT completely abrogated the anti-proliferative effects, and apoptosis induced by Cud C in CRC. …”
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Novel gel-associated drug loaded nanocarriers for intratumoural delivery by Štaka, Ivana

“…The lipid core of the NCs was suitable for encapsulation of anticancer drugs: docetaxel (DCX) and 4N-myristoyl-gemcitabine (GEM C14). NCs with diameters of 40 and 80 nm and with zeta potential values of ~ -4 ± 1 to –19 ±1 mV were produced. …”
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Low molecular mass nucleoside gelators for intra-tumoural drug delivery by Skilling, Kathryn J.

“…Using a minimal amount of ethanol and an ‘anti-solvent’ switch gelation method a gelating system derived from the N-myristoyl derivative, containing a solvent volume fraction (ΦSOL) of 0.40 was found to have the most advantageous mechanical and structural properties; a crosslinked nanofibrillar network, established by rheological measurements and microscopy (TEM). …”
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