Search Results - "morphine"
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The combination of mitragynine and morphine prevents the development of morphine tolerance in mice
Published 2013“…In the present study, we investigated the enhancement of analgesic action of MG when combined with morphine and the effect of the combination on the development of tolerance towards morphine. …”
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Priming dose of morphine/methamphetamine combination induced stereotyped behavior in morphine/methamphetamine-dependent mice
Published 2015“…The aim of this study is to compare the behavioral effects of priming dose in reinstatement model of morphine- and morphine/methamphetamine-dependent mice. …”
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Randomised double-blind comparison of morphine vs a morphine-alfentanil combination for patient-controlled analgesia
Published 2002“…In a randomized, double-blind study, I compared a combination of morphine and alfentanil with morphine alone for patient-controlled analgesia after Caesarean section under spinal anesthesia.…”
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Fluorescently labeled morphine derivatives for bioimaging studies
Published 2018“…Opioids, like morphine, are the mainstay analgesics for the treatment and control of pain. …”
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Effects of Erythroxylum Cuneatum (Miq.) Kurz on cellular and synaptic adaptation of chronic morphine-addicted human neuroblastoma cell line at protein level
Published 2017Subjects: “…Morphine - adverse effects…”
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The effect of dose on the intensity of dependence in morphine-dependent mice
Published 2015“…Therefore, in this study we aim to investigate the effects of different morphine dose (3.75 - 10 mg/kg) towards intensity of morphine dependence in adult Swiss albino mice. …”
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The effect of postnatal morphine exposure on spinal processing of sensory inputs
Published 2025Subjects: “…postnatal morphine exposure…”
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Novel Approaches Towards the Synthesis of Morphinan Derivatives
Published 2023Subjects: “…morphine…”
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Enhanced antinociceptive effects of mitragynine in combination with morphine via opioid receptors activation
Published 2014“…The management of chronic pain is one of the greatest challenges in modern medicine. Opiates such as morphine have been used to treat pain for centuries. …”
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Morphine antidependence of Erythroxylum cuneatum (Miq.) kKurz in neurotransmission processes in vitro
Published 2016“…The present study was designed to determine the effect of the alkaloid extract of Erythroxylum cuneatum (E. cuneatum) against chronic morphine and the influences of E. cuneatum on neurotransmission processes observed in vitro. …”
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Erythroxylum cuneatum enhanced receptor internalisation on morphine-desensitised neuroblastoma cells line
Published 2025“…Chronic morphine exposure disrupts receptor signalling by inhibiting receptor internalisation, leading to receptor desensitisation and reduced availability of active receptors. …”
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Andrographis Paniculata And Curcuma Xanthorrhiza Extracts And Active Constituents Inhibit Morphine Glucuronidation
Published 2016“…Aqueous extract moderately inhibited morphine glucuronidation compared to andrographolide and ethanolic extract. …”
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Mitragynine attenuates morphine withdrawal effects in rats—a comparison with methadone and buprenorphine
Published 2020“…Methods: Based on the morphine withdrawal model, rats were morphine treated with increasing doses from 10 to 50 mg/kg twice daily over a period of 6 days. …”
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Distinct role of kappa opioid receptor in attenuating relapse to morphine/methamphetamine (polydrug) dependence
Published 2017“…A combination of 0.3 mg/kg buprenorphine and 1.0 mg/kg naltrexone treatment shows a promising result due to its ability to attenuate reinstatement (relapse) in morphine/methamphetamine (polydrug)-dependent mice in a conditioned place preference (CPP) model. …”
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Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models
Published 2021“…A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days.…”
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The influence of duration of confinement towards morphine dependence intensity in conditioned place preference (CPP) model
Published 2015“…During conditioning phase, the mice received 7.5 mg/kg morphine and saline through intraperitoneal route on alternate day for 6 days. …”
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Establishment of human neuroblastoma cell-line (SK-N-SH) as an in vitro model of morphine addiction
Published 2021“…However, addiction and overdose liabilities before morphine usage are also common. Morphine addiction is observed and studied from various perspectives; tolerance, dependence, and withdrawal. …”
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The Determination of Morphine in the Larvae of Calliphora stygia using Flow Injection Analysis and HPLC with Chemiluminescence Detection
Published 2006“…Larvae of C. stygia were reared on minced meat substrates that had been spiked with varying concentrations of morphine. Morphine concentrations were chosen to reflect typical levels in human tissues from opiate overdose victims. …”
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A comparison of patient-controlled analgesia with oxycodone and morphine after total abdominal hysterectomy surgery
Published 2018“…We compared the analgesic profile between patient-controlled analgesia (PCA) using oxycodone and morphine in post total abdominal hysterectomy patients. …”
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