Search Results - "mesenchymal stem cell"
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Mesenchymal stem cell-mediated immunomodulation of microglia
Published 2013“…An approach for this is the utilisation of mesenchymal stem cells (MSC). This study explores the mechanisms through which MSC modulate inflammatory responses of microglia. …”
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Immunomodulatory potential of mesenchymal stem cells on microglia
Published 2012“…Accordingly, management of neuroinflammation must include an understanding of conditions that trigger neurotoxic responses by microglia and deciphering strategies to maintain their neuroprotective phenotype. Mesenchymal stem cells (MSC) are stem cells with great capacity for immunomodulation on a wide range of immune cells. …”
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Mesenchymal stem cell-mediated T cell immunosuppression
Published 2017“…Besides being a pool forstromal cells and connective tissues, the mesenchymal stem cells (MSCs) as well exert a potent immunosuppression against almost all types of immune cells, particularly T cells. …”
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Rescue of photoreceptor with human mesenchyme stem cell and human mesenchyme stem cell expressing erythropoietin in total degeneration of retina animal model
Published 2022“…Purpose: This study aimed to investigate the efficacy of human-derived umbilical cord mesenchymal stem cells (HDUMSC) and human-derived umbilical cord mesenchymal stem cells expressing erythropoietin (HDUMSC-EPO) to rescue total degenerated retina in a rat model. …”
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Visualization and Modeling of the In Vivo Distribution of Mesenchymal Stem Cells
Published 2017“…This unit describes a protocol for elucidating the in vivo disposition of administered mesenchymal stem cells (MSCs). Specifically, direct visualization of donor cell spatiotemporal distribution and assessment of donor cell quantity in recipient organs are described. …”
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Mesenchymal stem cell therapy for injured growth plate
Published 2013“…Established therapies for injured physis only address related complications. Mesenchymal stem cells (MSCs) are multipotent cells which are capable of differentiating into various cells of the musculoskeletal system. …”
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Inhibitory effect of mesenchymal stem cells on lymphocyte proliferation.
Published 2008“…We investigated the mechanism underlying the inhibitory effect of rat mesenchymal stem cells (MSCs) on non-specific mitogen-stimulated lymphocytes (LCs) and lymphoblasts (LBs). …”
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Empowering mesenchymal stem cells for ocular degenerative disorders
Published 2019“…Multipotent mesenchymal stem cells (MSCs) have been employed in numerous pre-clinical and clinical settings for various diseases. …”
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Mesenchymal stem cell and microglia crosstalk in an inflammatory paradigm
Published 2013Subjects: “…Mesenchymal Stem Cell Transplantation…”
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Mesenchymal stem cells: from stem cells to sarcomas
Published 2016“…Mesenchymal stem cells (MSCs) have garnered vast interests in clinical settings, especially in regenerative medicine due to their unique properties—they are reliably isolated and expanded from various tissue sources; they are able to differentiate into mesodermal tissues such as bones, cartilages, adipose tissues, and muscles; and they have unique immunosuppressive properties. …”
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Labeling of mesenchymal stem cells for MRI with single-cell sensitivity
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Multi-lineage differentiation of mesenchymal stem cells - To Wnt, or not Wnt
Published 2015“…Mesenchymal stem cells (MSCs) are multipotent precursor cells originating from several adult connective tissues. …”
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Effects of inflammatory mediators on bone marrow mesenchymal stem cells
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The effect of human Mesenchymal stem cell on neutrophil oxidative burst
Published 2010“…Objective: Mesenchymal stem cells (MSC) are multipotent, non-haematopoietic stem cells that are capable of differentiating into different varieties of mature cell types such as osteoblasts, chondrocytes, adipocytes. and myoblasts. …”
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Cellular reparative mechanisms of mesenchymal stem cells for retinal diseases
Published 2017“…The use of multipotent mesenchymal stem cells (MSCs) has been reported as promising for the treatment of numerous degenerative disorders including the eye. …”
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Immunomodulatory Effects of Human Mesenchymal Stem Cells on Neutrophil Functions
Published 2011“…To maintain normal tissue homeostasis, the dual roles of neutrophils are important but they need to be carefully modulated.Mesenchymal stem cells (MSC) are non-haematopoietic, multipotent cells that exert immunomodulatory activity on immune cells. …”
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The crosstalk between mesenchymal stem cells and damaged cartilage in osteoarthritis
Published 2020“…Human cartilage contains multipotent stem cells, namely mesenchymal stem cells (MSCs) which are progenitors of connective tissue that play homeostatic and reparative roles. …”
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Nitric oxide modulation in neuroinflammation and the role of mesenchymal stem cells
Published 2021“…Excessive nitric oxide causes neuronal toxicity and death and mesenchymal stem cells can be used as an approach to limit the neuronal damage caused by neuroinflammation. …”
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Optimization of pre-transplantation conditions to enhance the efficacy of mesenchymal stem cells
Published 2015“…Mesenchymal stem cells (MSCs) are considered a potential tool for cell based regenerative therapy due to their immunomodulatory property, differentiation potentials, trophic activity as well as large donor pool. …”
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