Search Results - "melanoma"

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    Understanding Proteolytic Processing of Melanoma Cell Adhesion Molecule (MCAM) in Cutaneous Melanoma by George, Tenielle

    Published 2023
    “…Melanoma is a type of skin cancer and is one of the most common cancers in Australia. …”
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    Anorectal melanoma – a report by Raja, Hisham, S., Kumar, Alif Gul, Yunus Gul

    Published 2006
    “…A review of the English literature confirms that anorectal melanoma is a rare tumour with dismal prognosis. Delay in diagnosis and the inherent aggressive systematic activity of the tumour at the time of diagnosis have been postulated as factors contributing to the poor prognosis. …”
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    The association of host and genetic melanoma risk factors with Breslow thickness in the Western Australian Melanoma Health Study by Cadby, G., Ward, S., Cole, J., Moses, Eric, Millward, M., Palmer, L.

    Published 2014
    “…Background: Breslow thickness is the most important predictor of survival in localized malignant melanoma. A number of melanoma risk factors have been shown to be associated with Breslow thickness; however, the role of genetic loci has been little investigated to date. …”
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    Lymphovascular invasion in melanoma and breast cancer by Safuan, Sabreena

    Published 2012
    “…In addition, vascular invasion in melanoma is mainly lymphatic vessel invasion with H&E assessment underestimating its incidence. …”
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    Ubiquitination and adaptive responses to BRAF inhibitors in Melanoma by Saei, A., Eichhorn, Pieter

    Published 2018
    “…Here we report the ubiquitin specific peptidase 28/F-box WD repeat-containing protein 7 (USP28/FBW7) complex functions as a negative regulator of mitogen-activated protein kinase (MAPK) pathway by targeting v-raf murine sarcoma viral oncogene homolog B (BRAF) for degradation, a process which is lost in a large proportion of BRAF mutant melanoma patients, resulting in resistance to BRAF inhibitor therapies.…”
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    Primary Malignant Melanoma of Vagina: The Options of Management. by Ng, BK, Lim, PS, Ng, YL, Kew, TY, Abdul Kadir AK, Hatta M

    Published 2014
    “…The treatment options for vaginal melanoma were reviewed.…”
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    MCAM in Melanoma Metastasis: The Role of Putative Endocytosis Motifs by Harfield, Jake

    Published 2021
    “…Melanoma cell adhesion molecule (MCAM) is a marker of melanoma metastasis and contributes to melanoma progression but how MCAM is sorted and recycled through the cell is unknown. …”
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    The effect on melanoma risk of genes previously associated with telomere length by Iles, M., Bishop, D., Taylor, J., Hayward, N., Brossard, M., Cust, A., Dunning, A., Lee, J., Moses, Eric, Akslen, L., Andresen, P., Avril, M., Azizi, E., Scarra, G., Brown, K., Debniak, T., Elder, D., Friedman, E., Ghiorzo, P., Gillanders, E., Goldstein, A., Gruis, N., Hansson, J., Harland, M., Helsing, P., Hoçevar, M., Hoiom, V., Ingvar, C., Kanetsky, P., Landi, M., Lang, J., Lathrop, G., Lubinski, J., Mackie, R., Martin, N., Molven, A., Montgomery, G., Novakovi, S., Olsson, H., Puig, S., Puig-Butille, J., Radford-Smith, G., Randerson-Moor, J., Van Der Stoep, N., Van Doorn, R., Whiteman, D., Macgregor, S., Pooley, K., Ward, S., Mann, G., Amos, C., Pharoah, P., Demenais, F., Law, M., Bishop, J., Barrett, J.

    Published 2014
    “…A genetic score that predicts telomere length, derived from these seven SNPs, is strongly associated (P = 8.92x10-9, two-sided) with melanoma risk. This demonstrates that the previously observed association between longer telomere length and increased melanoma risk is not attributable to confounding via shared environmental effects (such as ultraviolet exposure) or reverse causality. …”
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