Search Results - "mTOR"

A Germline MTOR Mutation in Aboriginal Australian Siblings with Intellectual Disability, Dysmorphism, Macrocephaly, and Small Thoraces by Baynam, G., Overkov, A., Davis, M., Mina, K., Schofield, L., Allcock, R., Laing, N., Cook, M., Dawkins, Hugh, Goldblatt, J.

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Discovery of a highly active anticancer analogue of cardamonin that acts as an inducer of caspase-dependent apoptosis and modulator of the mTOR pathway by Khaled bin Break, Mohammed, Hossan, Md Shahadat, Khooa, Yivonn, Chow, Sek Chuen, Wiart, Christophe, Bradshaw, Tracey D., Collins, Hilary, Khoo, Teng-Jin

Subjects: “…Cardamonin; Semi-synthesis; Cytotoxicity; Caspase; Cell-cycle arrest; mTOR…”
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Consequences of late-stage non-small cell lung cancer cachexia on muscle metabolic processes by Murton, Andrew J., Maddocks, Matthew, Stephens, Francis B., Marimuthu, Kanagaraj, England, Ruth, Wilcock, Andrew

Subjects: “…Muscle protein synthesis; proteolysis; cachexia; mTOR signalling; ubiquitin proteasome system…”
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Semi-synthesis of novel cardamonin analogues and identification of a highly active Cu(II)-cardamonin complex that inhibits migration and induces apoptosis via inhibition of mTOR ex... by Bin Break, Mohammed Khaled Ali

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Induction of autophagy by non-structural protein 6 in important animal and human coronaviruses by Daubrah-Scott, Tyler-Josh

Subjects: “…Coronaviruses; Autophagy; Non-structural protein 6; mTOR signalling; Host immunity evasion; Viral survival…”
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PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer by Serra, V., Scaltriti, M., Prudkin, L., Eichhorn, Pieter, Ibrahim, Y.H., Chandarlapaty, S., Markman, B., Rodriguez, O., Guzman, M., Rodriguez, S., Gili, M., Russillo, M., Parra, J.L., Singh, S., Arribas, J., Rosen, N., Baselga, J.

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