Search Results - "light sheet fluorescence microscopy"

Endolymph movement visualized with light sheet fluorescence microscopy in an acute hydrops model by Brown, Daniel, Pastras, C., Curthoys, I., Southwell, C., Van Roon, L.

“…Here we have taken the novel approach of injecting, via a glass micropipette, fluorescein isothiocyanate–dextran (FITC-dex) and artificial endolymph into scala media of anaesthetized guinea pigs, with subsequent imaging of the inner ear using Light Sheet Fluorescence Microscopy (LSFM) as a means to obtain highly resolved 3D visualization of fluid movements. …”
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Sensitivity of the cochlear nerve to acoustic and electrical stimulation months after a vestibular labyrinthectomy in guinea pigs by Brown, Daniel, Mukherjee, P., Pastras, C., Gibson, W., Curthoys, I.

“…Here, we have performed a unilateral vestibular labyrinthectomy in normally hearing guinea pigs, and allowed them to recover for either 6 weeks, or 10 months, before assessing morphological and functional changes related to cochlear implantation. Light sheet fluorescence microscopy was used to assess gross morphology throughout the entire ear. …”
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