Search Results - "ion channel"

Stochastic models of ion channels by Ball, Sue

“…The model is adapted and extended to demonstrate how properties of the calcium ion-activated potassium ion channel may be modelled. A two-state stochastic model for ion channels which incorporates time interval omission is examined. …”
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Action of philanthotoxin on ion channels of arthropod muscle by Khan, Tanwir Rahman

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Novel combinations of ion channel inhibitors for treatment of neurotrauma by O'Hare Doig, R., Fitzgerald, Melinda

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Investigation into the ion channels and plasma membrane properties of white adipocytes by Bentley, Donna C.

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Investigating the pharmacology of ladybird alkaloids on ligand-gated ion channels by Patel, Rohit

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Sinusoidal voltage protocols for rapid characterisation of ion channel kinetics by Beattie, Kylie, Hill, Adam P., Bardenet, Rémi, Cui, Yi, Vandenberg, Jamie I., Gavaghan, David J., de Boer, Teun P., Mirams, Gary R.

“…Our technique allows rapid collection of consistent and high quality data, from single cells, and produces more predictive mathematical ion channel models than traditional approaches.…”
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Benzamil sensitive ion channels contribute to volume regulation in canine chondrocytes by Lewis, R., Feetham, C.H., Gentles, L., Penny, J., Tregilgas, L., Tohami, W., Mobasheri, Ali, Barrett-Jolley, Richard

“…In this study, we investigated whether canine chondrocytes express functional ENaC/Deg-like ion channels and, if so, what their function may be. …”
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Investigating the role of ion channels across the fetomaternal interface of the human placenta by Ali, Tayyba Yasmin

“…The effects of a variety of ion channel modulators along with tissue oxygenation (20%, 5% and 2% O2) were also investigated on the vascular response of CPA and SVA. …”
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Molecular actions of pyrethroids on ion channels in the maize weevil, Sitophilus zeamais by Araújo, Rúbia Aparecida de

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Hierarchical Bayesian inference for ion channel screening dose-response data by Johnstone, Ross H., Bardenet, Rémi, Gavaghan, David J., Mirams, Gary R.

“…We demonstrate the use of the tool on a recently published dataset on multiple ion channel inhibition by multiple drug compounds. We compare the maximum likelihood, Bayesian and hierarchical Bayesian approaches. …”
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Functional studies of insecticides and acaricides acting on ligand-gated ion channels by Iqbal, Sofia

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A New Neuron Ion Channel Model with Noisy Input Current by Khudhur, Ahmed Mahmood, Abdalla, Ahmed N.

“…The data processing fundamental problem affects all aspects of nervous-system function by the noise of ion channels. The conducting and non conducting of ion channels depends on random transitions of channel noise, which affect the states of several numbers of gates in every single individual ion channel. …”
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Development of Neuron Ion Channel Model using Colored Noise Terms in the Conductance by Khudhur, Ahmed M., Hashim, Yasir, Abdalla, Ahmed N.

“…The aim of this study is the ion channel model with noise variance as approximations to the HodgkinHuxley model proposed, due to the Hodgkin-Huxley model affected when inserting some colored noise terms inside the conductances, where those effects captured by colored noise because of the gate multiplicity. …”
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INVESTIGATING THE NON-ION CHANNEL EFFECTS OF CFTR MODULATORS ON INNATE IMMUNE VIRAL RESPONSES by Garratt, L., Looi, K., Martinovich, K., Iosifidis, T., Ling, K., Shaw, N., Montgomery, S., Kicic-Starcevich, E., Sutanto, E., Kicic, Anthony, Stick, S.

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Optimization and improvement of hodgkin-huxley model under the influence of ion channel noise in neurons by Khudhur, Ahmed Mahmood

“…In recent years, it has been argued and shown experimentally that ion channel noise in neurons can cause fundamental effects on the neuron’s dynamical behavior. …”
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Specific ion channels contribute to key elements of pathology during secondary degeneration following neurotrauma by O'Hare Doig, R., Chiha, W., Giacci, M., Yates, N., Bartlett, C., Smith, N., Hodgetts, S., Harvey, A., Fitzgerald, Melinda

“…Changes in Ca 2+ flux are associated with metabolic and structural changes, but it is not yet clear how flux through specific ion channels contributes to the various pathologies. …”
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Ion Channel Mimetic Chronopotentiometric Polymeric Membrane Ion Sensor for Surface-Confined Protein Detection by Xu, Y., Bakker, Eric

“…The operation of ion channel sensors is mimicked with functionalized polymeric membrane electrodes, using a surface confined affinity reaction to impede the electrochemically imposed ion transfer kinetics of a marker ion. …”
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Comparison of ion channel inhibitor combinations for limiting secondary degeneration following partial optic nerve transection by Toomey, L., Bartlett, C., Majimbi, Maimuna, Gopalasingam, G., Rodger, J., Fitzgerald, Melinda

“…Following neurotrauma, secondary degeneration of neurons and glia adjacent to the injury leads to further functional loss. A combination of ion channel inhibitors (lomerizine + oxATP + YM872) has been shown to be effective at limiting structural and functional loss due to secondary degeneration. …”
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Acute Cellular and Functional Changes With a Combinatorial Treatment of Ion Channel Inhibitors Following Spinal Cord Injury by O’Hare Doig, R.L., Santhakumar, S., Fehily, B., Raja, S., Solomon, T., Bartlett, C.A., Fitzgerald, Melinda, Hodgetts, S.I.

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The effects of a combination of ion channel inhibitors in female rats following repeated mild traumatic brain injury by Mao, Yilin, Black, A., Milbourn, H., Krakonja, S., Nesbit, Michael, Bartlett, C., Fehily, B., Takechi, Ryu, Yates, N., Fitzgerald, Melinda

“…The authors assessed the effects of a combination of ion channel inhibitors (ICI) following repeated mTBI (rmTBI). …”
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