Search Results - "high-throughput screening"

A high-throughput screen to identify novel calcineurin inhibitors by Margassery, L., Kennedy, J., O'Gara, Fergal, Dobson, A., Morrissey, J.

Get full text

Combinatorial Biomolecular Nanopatterning for High-Throughput Screening of Stem-Cell Behavior by Amin, Yacoub Y. I., Runager, Kasper, Simoes, Fabio, Celiz, Adam, Taresco, Vincenzo, Rossi, Roberto, Enghild, Jan J., Abildtrup, Lisbeth A., Kraft, David C. E., Sutherland, Duncan S., Alexander, Morgan R., Foss, Morten, Ogaki, Ryosuke

Get full text

High throughput screening for discovery of materials that control stem cell fate by Patel, Asha K., Tibbitt, Mark, Celiz, Adam D., Davies, Martyn C., Langer, Robert, Denning, Chris, Alexander, Morgan R., Anderson, Daniel G.

Subjects: “…Stem cells; Differentiation; Biomaterials; High throughput screening; 3D…”
Get full text

Development of a high-throughput screen for the study of CRISPR spacer acquisition by Braithwaite, Jack

Subjects: “…High-throughput screen…”
Get full text

Discovering novel immune-modulatory monosaccharides using high-throughput screening strategies by Alobaid, Meshal

“…In this project, I used a high throughput screening strategy to investigate immune modulatory properties of a combinatorial library of immobilised synthetic monosaccharides with a particular focus on their ability to modulate key phenotypic and functional properties of human DCs. …”
Get full text

PERSONALIZED CELL CULTURE MODEL FOR HIGH-THROUGHPUT SCREENING FOLLOWING CFTR CORRECTION by Looi, K., Garratt, L., Sutanto, E., Kicic, Anthony, Stick, S., Arest, C.F.

Get full text

Applications of a high-throughput screen detecting CRISPR-Cas spacer acquisition by Cannon, Christopher

Get full text

Virtual High Throughput Screening For Avian Influenza (H5nl) Neuraminidase Inhibitors by Ismail, Nurul Izza

Get full text
Get full text

High-throughput screening of pome metagenomic DNA libraries for bioprospecting novel cellulose-degrading enzymes by Ibrahim Ali , Noorbatcha, Hamzah, Mohd. Salleh

“…Keywords: Cellulose-degrading enzyme; Palm oil mill effluent (POME); Enrichment, metagenomic DNA library; High-throughput screening; Fluorogenic substrate…”
Get full text
Get full text
Get full text
Get full text

Ultra-high-throughput screening of beta glucoside kinase random mutagenesis library for phosphorus-sulfur bond Formation by Ibrahim Ali, Noorbatcha, Hamzah, Mohd. Salleh

Get full text
Get full text
Get full text
Get full text

Identification of novel ‘inks’ for 3D printing using high throughput screening: bioresorbable photocurable polymers for controlled drug delivery by Louzao, Iria, Koch, Britta, Taresco, Vincenzo, Ruiz Cantu, Laura, Irvine, Derek J., Roberts, Clive J., Tuck, Christopher J., Alexander, Cameron, Hague, Richard J.M., Wildman, Ricky D., Alexander, Morgan R.

Get full text

Development and validation of high resolution melting assays for high-throughput screening of BDNF rs6265 and DAT1 rs40184 by Faris, Asraa, Md Yusof, Hadri Hadi, Zainal Abidin, Shahidee, Habib, Omar, Cheah, Pike See, Stanslas, Johnson, Ibrahim, Normala, Lye, Munn Sann, Veerakumarasivam, Abhi, Rosli, Rozita, Ling, King Hwa

“…Conclusions: The application of HRM can accurately determine the genotype of BDNF rs6265 and DAT1 rs40184 SNPs, making it a promising tool for rapid and high-throughput screening of targeted SNPs in a large population study.…”
Get full text
Get full text

High-Throughput Screening Assay In 384-Well Format For The Identification Of Anti-Trypanosomal Agents Against Trypanosoma Brucei Rhodesiense And Mode Of Cell Death Study by Lim, Kah Tee

“…In order to accelerate the discovery of novel leads for the treatment of Human African Trypanosomiasis (HAT), it is necessary to have a simple and sensitive assay to identify positive hits by whole cell viability based high-throughput screening (HTS). In this study, the HTS assay was developed in 384-well format using clear plate and black plate, for comparison. …”
Get full text
Get full text

A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells by Arruda, Maria Augusta, Stoddart, Leigh A., Gherbi, Karolina, Briddon, Stephen J., Kellam, Barrie, Hill, Stephen J.

Subjects: Get full text

Recombinant expression of native Tritrypticin and optimisation of an In vivo biosynthesis platform for high-throughput peptide therapeutics discovery by Mahendran, Arun Suria Karnan

Subjects: “…DnaB intein; directed evolution; error-prone PCR; E. coli BL21 (DE3); pTWIN1 plasmid; outer membrane protein A (OmpA); novel signal peptide 4 (NSP4); recombinant antimicrobial peptide production; recombinant expression optimisation; high-throughput screening assays; bacterial agar screening; mutant peptide library screening; enhanced mutant AMP activity; inducible intein-mediated experssion system; antimictobial inhibition zones…”
Get full text

Enrichment strategy to enhance screening for novel cellulose-degrading enzymes from Malaysian palm oil mill effluent by constructing functional DNA metagenomic libraries by Ibrahim Ali , Noorbatcha, Hamzah, Mohd. Salleh

“…Key words: cellulose-degrading enzyme, Malaysian palm oil mill effluent (POME), enrichment, metagenomic DNA library, high-throughput screening. …”
Get full text
Get full text
Get full text
Get full text

Purinergic P2X7 Receptor Antagonists: Chemistry and Fundamentals of Biological Screening by Gunosewoyo, Hendra, Coster, M., Bennett, M., Kassiou, M.

“…This receptor has been implicated in numerous diseases and many structurally diverse ligands have been discovered via high throughput screening. This perspective will attempt to highlight some of the most recent key findings in both the biology and chemistry.…”
Get full text

Inhibitors of Leishmania mexicana phosphoglycerate mutase identified by virtual screening and verified by inhibition studies by Fazia Adyani Ahmad Fuad, Houston, Douglas R., Michels, Paul A.M., Fothergill-Gillmore, Linda A., Walkinshaw, Malcolm D.

“…In addition, three compounds from the Library of Pharmacologically Active Compounds (LOPAC) were selected from the published results of high-throughput screening of this library. The inhibitory effects of these compounds were tested at a fixed concentration of 1 mM. …”
Get full text
Get full text

Inhibitors of leishmania mexicana phosphoglycerate mutase identified by virtual screening and verified by inhibition studies by Ahmad Fuad, Fazia Adyani, Houston, Douglas Robert, Michels, Paul A M, Fothergill- Gilmore, Linda A., Walkinshaw, Malcolm Douglas

“…In addition, three compounds from the Library of Pharmacologically Active Compounds (LOPAC) were selected from the published results of high-throughput screening of this library. The inhibitory effects of these compounds were tested at a fixed concentration of 1 mM. …”
Get full text
Get full text
Get full text
Get full text

Development Of Fӧrster Resonance Energy Transfer Based Homogeneous Immunoassays For Determination Of (R)-Methadone by Ooi, May Yui

“…Oleh itu, asai “high throughput screening” adalah penting untuk meningkatkan kecekapan analisis perubatan. …”
Get full text
Get full text