Search Results - "cognitive decline"

Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline. by Ryan, Joanne, Storey, Elsdon, Murray, Anne M, Woods, Robyn L, Wolfe, Rory, Reid, Christopher, Nelson, Mark R, Chong, Trevor TJ, Williamson, Jeff D, Ward, Stephanie A, Lockery, Jessica E, Orchard, Suzanne G, Trevaks, Ruth, Kirpach, Brenda, Newman, Anne B, Ernst, Michael E, McNeil, John J, Shah, Raj C, ASPREE Investigator Group

“…CONCLUSIONS: There was no evidence that aspirin was effective in reducing risk of dementia, MCI, or cognitive decline. Follow-up of these outcomes after initial exposure is ongoing. …”
Get full text
Get full text

Cardiovascular risk factors and cognitive decline in older people with type 2 diabetes by Feinkohl, Insa, Keller, Markéta, Robertson, Christine M., Morling, Joanne R., McLachlan, Stela, Frier, Brian M., Deary, Ian J., Strachan, Mark W.J., Price, Jackie F.

“…AIMS/HYPOTHESIS: The aim of this work was to assess the role of well-established cardiovascular risk factors in the late-life cognitive decline of patients with type 2 diabetes. …”
Get full text

Longitudinal cognitive decline in the AIBL cohort: The role of APOE e4 status by Albrecht, Matthew, Szoeke, C., Maruff, P., Savage, G., Lautenschlager, N., Ellis, K., Taddei, K., Martins, R., Masters, C., Ames, D., Foster, Jonathan

“…Healthy Controls with an ε4 allele manifested a modest acceleration in cognitive decline over 36 months on measures of verbal episodic memory. …”
Get full text

Longitudinal cognitive decline in the AIBL cohort: the role of APOE ε4 status by Foster, J., Albrecht, Matthew, Szoeke, C., Maruff, P., Savage, G., Lautenschlager, N., Ellis, K., Taddei, K., Martins, R., Masters, C., Ames, D.

Get full text

Amyloid ß–associated cognitive decline in the absence of clinical disease progression and systemic illness by Harrington, K., Lim, Y., Ames, D., Hassenstab, J., Laws, Simon, Martins, R., Rainey-Smith, S., Robertson, J., Rowe, C., Salvado, O., Doré, V., Villemagne, V., Snyder, P., Masters, C., Maruff, P.

“…© 2017 The Authors Introduction High levels of amyloid ß (Aß) are associated with cognitive decline in cognitively normal (CN) older adults. …”
Get full text

Tocotrienol-rich fraction supplementation reverses age related cognitive decline in aged rats by Nursiati, MT, Mohamad Fairuz, Y, Azian, AL, Wan Zurinah, WN, Musalmah, M

Get full text
Get full text

Caregiver Burden is Associated with Cognitive Decline and Physical Disability of Elderly Post-Stroke Patients by Othman, Zahiruddin, Siong, Teck Wong, Drahman, Ismail, Zakaria, Rahimah

“…Caregiver burden was significant, albeit weakly, correlated with cognitive decline (r=0.362, P 0.001) and physical disability (r=0.316, P=0.002) of elderly post-stroke patients. …”
Get full text
Get full text

Validation of the Malay Version of Short Informant Questionnaire on Cognitive Decline in the Elderly (MS-IQCODE) by Othman, Zahiruddin, Siong, Teck Wong, Drahman, Ismail, Kok, Wei Wee

“…Aims: The short Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) is a self-administered informant- based report on cognitive decline. …”
Get full text
Get full text

Atrial fibrillation and cognitive decline-the role of subclinical cerebral infarcts: The atherosclerosis risk in communities study by Chen, L., Lopez, F., Gottesman, R., Huxley, Rachel, Agarwal, S., Loehr, L., Mosley, T., Alonso, A.

“…BACKGROUND AND PURPOSE: The mechanism underlying the association of atrial fibrillation (AF) with cognitive decline in stroke-free individuals is unclear. …”
Get full text

Impact of physical activity on cognitive decline, dementia and its subtypes: meta-analysis of prospective studies by Guure, Chris Bambey, Ibrahim, Noor Akma, Adam, Mohd Bakri, Md Said, Salmiah

“…Our findings suggest that physical activity is more protective against Alzheimer’s disease than it is for all-cause dementia, vascular dementia, and cognitive decline.…”
Get full text
Get full text

Probucol prevents blood–brain barrier dysfunction and cognitive decline in mice maintained on pro-diabetic diet by Mamo, John, Lam, Virginie, Brook, E., Mooranian, A., Al-Salami, Hani, Fimognari, N., Nesbit, M., Takechi, Ryu

“…Co-provision of probucol with high-fat and high-fructose diet completely prevented the cognitive decline and blood–brain barrier dysfunction. …”
Get full text

More ulam for your brain: a review on the potential role of ulam in protecting against cognitive decline by You, Yeexing, Suzana Shahar, Hasnah Haron, Hanis Mastura Yahya

“…The objective of this review article was to highlight the total phenolic content (TPC) and antioxidant activity of ulam and the roles of phenolic content that can contribute to attenuation of cognitive decline. The review includes randomized controlled trial and experimental studies from year 2007 to 2017. …”
Get full text
Get full text

Microstructural white matter changes mediated age- related cognitive decline in the Montreal Cognitive Assessment (MoCA) by Jolly, Todd, Cooper, Patrick, Wan Ahmadul Badwi, Syarifah Azizah, Phillips, Natalie, Rennie, Jaime, Levi, Christopher, Drysdale, Karen, Parsons, Mark, Michie, Patricia, Karayanidis, Frini

“…Although the relationship between aging and cognitive decline is well established, there is substantial individual variability in the degree of cognitive decline in older adults. …”
Get full text
Get full text
Get full text

Klotho allele status is not associated with Aß and APOE e4–related cognitive decline in preclinical Alzheimer's disease by Porter, T., Burnham, S., Milicic, L., Savage, G., Maruff, P., Lim, Y., Ames, D., Masters, C., Martins, R., Rainey-Smith, S., Rowe, C., Salvado, O., Groth, David, Verdile, Giuseppe, Villemagne, V., Laws, S.

“…Overall, previous associations reported between KL-VS and cognitive decline are not observed at the preclinical stages of AD. …”
Get full text

Art therapy and music reminiscence activity in the prevention of cognitive decline: Study protocol for a randomized controlled trial by Mahendran, R., Rawtaer, I., Fam, J., Wong, J., Kumar, Alan Prem, Gandhi, M., Jing, K., Feng, L., Kua, E.

“…Background: Attention has shifted to the use of non-pharmacological interventions to prevent cognitive decline as a preventive strategy, as well as for those at risk and those with mild cognitive impairment. …”
Get full text

Aspirin for the prevention of cognitive decline in the elderly: Rationale and design of a neuro-vascular imaging study (ENVIS-ion) by Reid, Christopher, Storey, E., Wong, T., Woods, R., Tonkin, A., Wang, J., Kam, A., Janke, A., Essex, R., Abhayaratna, W., Budge, M.

“…Given the limited access and high cost of MRI, RVI may prove useful as a tool for the identification of individuals at high risk for the development of cerebrovascular disease and cognitive decline.…”
Get full text

METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: an initiative of the Joint Programme for Neurodegenerative Disease Research by Dichgans, Martin, Wardlaw, Joanna, Smith, Eric, Zietemann, Vera, Seshadri, Sudha, Sachdev, Perminder, Biessels, Geert Jan, Fazekas, Franz, Benavente, Oscar, Pantoni, Leonardo, De Leeuw, Frank-Erik, Norrving, Bo, Matthews, Paul, Chen, Christopher, Mok, Vincent, Düring, Marco, Whiteley, Will, Shuler, Kirsten, Alonso, Alvaro, Black, Sandra E., Brayne, Carol, Chabriat, Hugues, Cordonnier, Charlotte, Doubal, Fergus, Duzel, Emrah, Ewers, Michael, Frayne, Richard, Hachinski, Vladimir, Ikram, Mohammad Arfan, Jessen, Frank, Jouvent, Eric, Linn, Jennifer, O'Brien, John, van Oostenbrugge, Robert, Malik, Rainer, Mazoyer, Bernard, Schmidt, Reinhold, Sposato, Luciano A., Stephan, Blossom, Swartz, Richard H., Vernooij, Meike, Viswanathan, Anand, Werring, David, Abe, Koji, Allan, Louise, Arba, Francesco, Diener, H.-C., Davis, S., Hankey, G., Lees, K.R., Ovbiagele, B., Weir, C., Bae, Hee-Joon, Bath, Philip M.W., Bordet, Regis, Breteler, Monique, Choi, Seong, Deary, Ian, DeCarli, Charles, Ebmeier, Klaus, Feng, Lei, Greenberg, Steven M., Ihara, Masafumi, Kalaria, Rajesh, Kim, SanYun, Lim, Jae-Sung, Lindley, Richard I., Mead, Gillian, Murray, Alison, Quinn, Terry, Ritchie, Craig, Sacco, Ralph, Al-Shahi Salman, Rustam, Sprigg, Nikola, Sudlow, Cathie, Thomas, Alan, van Boxtel, Martin, van der Grond, Jeroen, van der Lugt, Aad, Yang, Yuan-Han

Get full text

Cognitive impairment in stroke and multiple sclerosis by Belcher, Andrew

Subjects: “…Stroke; Cerebral vascular disease; Multiple sclerosis; cognitive decline…”
Get full text

Blood-brain barrier dysfunction precedes cognitive decline and neurodegeneration in diabetic insulin resistant mouse model: An implication for causal link by Takechi, Ryu, Lam, Virginie, Brook, Emily, Giles, Corey, Fimognari, Nicholas, Mooranian, Armin, Al-Salami, Hani, Coulson, Stephanie, Nesbit, Michael, Mamo, John

“…In C57BL/6J mice chronically ingested with a diet enriched in fat and fructose (HFF), Morris Water Maze (MWM) test indicated no significant cognitive decline after 4 weeks of HFF feeding compared to low-fat (LF) fed control. …”
Get full text
Get full text

A Polygenic Risk Score Derived From Episodic Memory Weighted Genetic Variants Is Associated With Cognitive Decline in Preclinical Alzheimer's Disease by Porter, T., Burnham, S., Savage, G., Lim, Y., Maruff, P., Milicic, L., Peretti, M., Ames, D., Masters, C., Martins, R., Rainey-Smith, S., Rowe, C., Salvado, O., Taddei, K., Groth, David, Verdile, Giuseppe, Villemagne, V., Laws, Simon

Subjects: Get full text