Search Results - "cirrhosis"

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    The epidemiology of cirrhosis and abnormal liver function in the general population of the UK by Fleming, Catherine Mary

    Published 2010
    “…To estimate the incidence and prevalence of cirrhosis in the population of the UK 2. To describe the mortality associated with cirrhosis compared with the general population and the disease progression of cirrhosis 3. …”
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    Patient understanding of liver cirrhosis and improvement using multimedia education by Goldsworthy, Matthew A., Fateen, Waleed, Thygesen, Helene, Aldersley, Mark A., Rowe, Ian A., Jones, Rebecca L.

    Published 2017
    “…Objective: For patients to engage with the long-term management of liver cirrhosis, sufficient understanding of their condition is essential. …”
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    Quantitative magnetic resonance imaging to evaluate patients with liver cirrhosis by Scott, Robert A.D.

    Published 2020
    “…Most morbidity and mortality in patients with liver cirrhosis results from the development and progression of portal hypertension, characterised by increased intrahepatic resistance and splanchnic vasodilatation. …”
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    Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer by Ratib, Sonia, West, Joe, Crooks, Colin J., Fleming, Kate M.

    Published 2014
    “…OBJECTIVES: There is no routine registration of the occurrence of newly diagnosed cases of cirrhosis in the United Kingdom. This study seeks to determine precise estimates and trends of the incidence of cirrhosis in England, and directly compare these figures with those for the 20 most commonly diagnosed cancers in the United Kingdom. …”
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    Cohort study of the impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis by Foster, Graham R., Irving, William L., Cheung, Michelle C.M., Walker, Alex J., Hudson, Benjamin E., Verma, Suman, McLauchlan, John, Mutimer, David J., Brown, Ashley, Gelson, William T.H., MacDonald, Douglas C., Agarwal, Kosh

    Published 2016
    “…We compared outcomes in treated and untreated patients with decompensated cirrhosis. Methods: Patients with HCV and decompensated cirrhosis or at risk of irreversible disease were treated in an Expanded Access Programme (EAP) in 2014. …”
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    Risk of hepatocellular carcinoma among individuals with different aetiologies of cirrhosis: a population-based cohort study by West, Joe, Card, Timothy R., Aithal, Guruprasad P., Fleming, Kate M.

    Published 2017
    Subjects: “…Epidemiology; Cancer; Cirrhosis; Hepatocellular carcinoma; Incidence; Alcohol; Cryptogenic; Chronic viral hepatitis…”
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    SOX9 predicts progression towards cirrhosis in patients while its loss protects against liver fibrosis by Athwal, Varinder S., Pritchett, James, Llewellyn, Jessica, Martin, Katherine, Camacho, Elizabeth, Raza, Sayyid M.A., Phythian-Adams, Alexander, Birchall, Lindsay J., Mullan, Aoibheann F., Su, Kim, Pearmain, Laurence, Dolman, Grace, Zaitoun, Abed M., Friedman, Scott L., MacDonald, Andrew, Irving, William L., Guha, Indra N., Hanley, Neil A., Hanley, Karen Piper

    Published 2017
    “…In this study we show the prevalence of SOX9 in biopsies from patients with chronic liver disease correlated with fibrosis severity and accurately predicted disease progression towards cirrhosis. Inactivation of Sox9 in mice protected against both parenchymal and biliary fibrosis, improved liver function and ameliorated chronic inflammation. …”
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    Peak inflammation in atherosclerosis, primary biliary cirrhosis and autoimmune arthritis is counter-intuitively associated with regulatory T cell enrichment by Garetto, S., Trovato, A., Lleo, A., Sala, F., Martini, E., Betz, A., Norata, Giuseppe, Invernizzi, P., Kallikourdis, M.

    Published 2015
    “…We examined models of three different diseases caused by organ-specific autoimmune responses: primary biliary cirrhosis, atherosclerosis and rheumatoid arthritis (RA). …”
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