Search Results - "chromatin"

Chromatin accessibility in the liver and circulating immune cells of pigs, goats and chickens. by Giuffra, E., Munyard, Kylie, Goubil, A., Vincent-Naulleau, S., Esquerre, D., Djebali, S., Foissac, S.

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Identification of the ISWI chromatin remodeling complex of the early branching Eukaryote Trypanosoma brucei by Stanne, Tara, Shankar Narayanan, Mani, Ridewood, Sophie, Ling, Alexandra, Witmer, Kathrin, Kushwaha, Manish, Wiesler, Simone, Wickstead, Bill, Wood, Jennifer, Rudenko, Gloria

“…ISWI chromatin remodelers are highly conserved in eukaryotes and are important for the assembly and spacing of nucleosomes, thereby controlling transcription initiation and elongation. …”
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Genome-wide mapping of transcriptional enhancer candidates using DNA and chromatin features in maize by Oka, Rurika, Zicola, Johan, Weber, Blaise, Anderson, Sarah N., Hodgman, Charlie, Gent, Jonathan I., Wesselink, Jan-Jaap, Springer, Nathan M., Hoefsloot, Hubb C.J., Turck, Franziska, Stam, Maike

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Sperm DNA fragmentation among smokers and non-smokers as measured by sperm chromatin dispersion test by Azizan, Azha Syahril, Mustafa, Kamarul Bahyah, Abdul Wahab, Azantee Yazmie, Ramli, Roszaman, Abu Ishak, Nurkhairulnisa

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Modelling of chromatin morphologies in breast cancer cells undergoing apoptosis using generalized Cauchy field. by Muniandy, Sithi V., Stanslas, Johnson

“…Chromatin morphologies in human breast cancer cells treated with an anti-cancer agent are analyzed at their early stage of programmed cell death or apoptosis. …”
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Low temperatures induce rapid changes in chromatin state and transcript levels of the cereal VERNALIZATION1 gene by Oliver, S., Deng, Weiwei, Casao, C., Trevaskis, B.

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Prophylactic effects of Nigella sativa extract and thymoquinone against cyclophosphamide-induced sperm head abnormalities and chromatin instability in mice by Abdul Rahman, Suzanah, Kamarzaman, Saheera

“…Sperm head abnormalities were classified into normal, lack-hook, banana-like form, amorphous and folded on themselves. Chromatin condensation was categorised into unstained, completely and partially-stained. …”
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Association of modified cytosines and the methylated DNA-binding protein MeCP2 with distinctive structural domains of lampbrush chromatin by Morgan, Gary T., Jones, Peter, Bellini, Michel

“…We have investigated the association of DNA methylation and proteins interpreting methylation state with the distinctive closed and open chromatin structural domains that are directly observable in the lampbrush chromosomes (LBCs) of amphibian oocytes. …”
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Function of MYST3 / MOZ: a histone acetyltransferase and chromatin regulator implicated in haematopoietic stem cell development and leukaemia by Monteiro, C.J.

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Finding potential cis-regulatory loci using allele-specific chromatin accessibility as weights in a kernel-based variance component test by Peralta, J., Almeida, M., Abraham, L., Moses, Eric, Blangero, J.

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The regulation of chromatin and transmission of epigenetic information by the heterochromatin protein 1, binding protein 3 (HP1BP3) in normal and colorectal cancer cells by Kattan, Shahad

“…Taken together, these findings point towards the important biological functions of HP1BP3 and its contribution in regulation of chromatin/EMT associated genes expression which consequently can be implicated in the pathogenesis of different types of FBXW7-mutated cancer.…”
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Epidrug mediated re-expression of miRNA targeting the HMGA transcripts in pituitary cells by Kitchen, Mark O., Yacub-Usman, Kiren, Emes, Richard D., Richardson, Alan, Clayton, Richard N., Farrell, William E.

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Origin-independent replication in Haloferax volcanii: RadA localisation, R-loops, and genomic rearrangements by Hodson, Katie

Subjects: “…Chromatin Immunoprecipitation Sequencing; FLAG-tagged RadA; RadA binding; Origin-independent replication; Recombination-dependent replication…”
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Lung function associated gene Integrator Complex subunit 12 regulates protein synthesis pathways by Kheirallah, Alexander K., de Moor, Cornelia H., Faiz, Alen, Sayers, Ian, Hall, Ian P.

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Translating lung function genome-wide association study (GWAS) findings: new insights for lung biology by Kheirallah, Alexander K., Miller, Suzanne, Hall, Ian P., Sayers, Ian

Subjects: “…ChIP-seq; Chromatin biology; Chronic obstructive pulmonary disease; Genome editing; Genome-wide association studies; Human tissue; Lung function; RNAseq; Single nucleotide polymorphism; Transgenic mouse…”
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Heterochromatin protein HP1BP3 modulates haematopoiesis and leukemogenesis by Almars, Amany

“…Histone PTMs impact the dynamic of the nucleosome, the fundamental unit of chromatin, through wrapping/unwrapping, assembly/disassembly to modulate the chromatin architecture, i.e. conversion from heterochromatin “inactive chromatin” to euchromatin “active chromatin”. …”
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Molecular prioritization strategies to identify functional genetic variants in the cardiovascular disease-associated expression QTL Vanin-1 by Kaskow, B., Diepeveen, L., Michael Proffitt, J., Rea, A., Ulgiati, D., Blangero, J., Moses, Eric, Abraham, L.

“…By combining 'gold standard' assays with in vivo assessments of chromatin accessibility, we greatly increase our confidence in the statistically assigned functional relevance. …”
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Role of RNF20 in cancer development and progression – a comprehensive review by Sethi, G., Shanmugam, M., Arfuso, Frank, Kumar, Alan Prem

“…Evolving strategies to counter cancer initiation and progression rely on the identification of novel therapeutic targets that exploit the aberrant genetic changes driving oncogenesis. Several chromatin associated enzymes have been shown to influence post-translational modification (PTM) in DNA, histones, and non-histone proteins. …”
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Novel functions of the MOZ double PHD finger domain by Deeves, Sian Elizabeth

“…Thus, our data suggest that like several other chromatin-associated proteins, MOZ is a multi-functional regulator of chromatin modification and gene expression.…”
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Reprogramming of the mouse Nanog gene in amphibian oocyte extracts by Bereketoğlu, Sidar

“…However, the epigenetic mechanisms associated with the reprogramming of Nanog expression are not fully understood. In mammalian chromatin, epigenetic control of gene expression includes DNA methylation and histone modifications. …”
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