Search Results - "autophagy"

The role of survivin in autophagy by Humphry, Nicola

Subjects: “…Survivin; lc3; Autophagy; Mitosis…”
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Autophagy, citrullination and cancer by Durrant, LG

Subjects: “…antigen presentation; autophagy; cancer; citrullination; peptidylarginine deiminases…”
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Cell-based assays for evaluation of autophagy in cancers by Pang, Siew Wai *, Awi, Noel Jacques *, Yap, Hooi Yeen *, Teow, Sin Yeang *

“…Autophagy is a cellular mechanism that degrades damaged organelles and misfolded proteins to maintain cellular homeostasis. …”
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Autophagy and cancer: taking the ‘toxic’ out of cytotoxics by Giuliani, C., Dass, Crispin

“…Objectives: Autophagy is the catabolic process that facilitates the degradation of proteins and organelles into recyclable nutrients for use by the cell. …”
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Interplay of autophagy and cancer stem cells in hepatocellular carcinoma by Wong, M. M. T., Chan, H. Y., Norazlin, A. A., Thamil Selvee, R., Bong, J. J., Ch’ng, E. S., Armon, Subasri, Peh, Suat Cheng *, Teow, Sin Yeang *

“…The impairment of autophagy is highly associated with the development and progression of HCC although autophagy may be involved in tumour-suppressing cellular events. …”
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ROS, autophagy, mitochondria and cancer: Ras, the hidden master? by Bellot, G., Liu, D., Pervaiz, Shazib

“…To that end, a number of key factors have been identified and thoroughly investigated over the past couple of decades, such as redox regulation of cell fate decisions, cellular metabolism and bioenergetics, autophagy induction as a survival signal, and how these pathways interplay with oncogene-induced transformation. …”
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Pharmacological modulation of apoptosis and autophagy in pancreatic cancer treatment by Stanslas, Johnson, Islam, Mohammad Kaisarul, Selvarajoo, Nityaa, Sagineedu, Sreenivasa Rao, Lian, Ho Kok, Lim, Jonathan Chee Woei

“…The cancer drugs that regulate autophagy in treating cancer can be categorized into three groups: i) direct autophagy inducers (e.g., rapamycin), ii) indirect autophagy inducers (e.g., resveratrol), and iii) autophagy inhibitors. …”
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Expression of autophagy and mitophagy markers in breast cancer tissues by Mustafa, Mohd Fazirul, Muhamad Saliluddin, Suhainizam, Fakurazi, Sharida, Tizen Laim, Nur Maya Sabrina, Md Pauzi, Suria Hayati, Nik Yahya, Nik Hasimah, Raja Gopal, Navarasi S., Abdullah, Maizaton Atmadini, Maniam, Sandra

“…ROS-induced mitochondrial damage is among the main intracellular signal inducers of autophagy. Autophagy is a cellular catabolic process that regulates protein and organelle turnover, while a selective form of autophagy, mitophagy, specifically targets dysfunctional mitochondrial degradation. …”
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Biphasic effects of autophagy on decompression bubble-induced endothelial injury by Wang, M., Zhang, K., Nie, S., Huang, G., Yi, H., He, C., Buzzacott, Peter, Xu, W.

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Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS) by Foggin, Sophie

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The anti-tumor effect of zinc on renal cell carcinoma by enhancing autophagy by Yu, Zhihai, Wu, Shaobo, Zhao, Qiurong, Guo, Yaochuan, Liu, Hengchuan, Huang, Xiao

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Metabolic stress and cancer: is autophagy the common denominator and a feasible target? by Giuliani, C., Dass, Crispin

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Biophysical studies of ligand selectivity for the hATG8 family of autophagy proteins by Butler, Kevin

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Association between autophagy and KRAS mutation with clinicopathological variables in colorectal cancer patients by Awi, Noel Jacques, Yap, Hooi Yeen, Subasri, A., Low, John Seng-Hooi, Peh, Kaik-Boo, Peh, Suat Cheng *, Lee, C. S., Teow, Sin Yeang *

“…Autophagy is a host defensive mechanism responsible for eliminating harmful cellular components through lysosomal degradation. …”
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Cardiomyocyte apoptosis vs autophagy with prolonged doxorubicin treatment: Comparison with osteosarcoma cells by Tacar, O., Indumathy, S., Tan, M., Baindur-Hudson, S., Friedhuber, A., Dass, Crispin

“…Conclusion In culture, cells of both cardiomyocytes and OS revealed a predominant pro-apoptotic response at the expense of autophagy, although both seemed to be occurring in vivo.…”
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Latrepirdine stimulates autophagy and reduces accumulation of a-synuclein in cells and in mouse brain by Steele, J., Ju, S., Lachenmayer, M., Liken, J., Stock, A., Kim, S., Delgado, L., Alfaro, I., Bernales, S., Verdile, Giuseppe, Bharadwaj, P., Gupta, V., Barr, R., Friss, A., Dolios, G., Wang, R., Ringe, D., Protter, A., Martins, R., Ehrlich, M., Yue, Z., Petsko, G., Gandy, S.

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Induction of autophagy by non-structural protein 6 in important animal and human coronaviruses by Daubrah-Scott, Tyler-Josh

Subjects: “…Coronaviruses; Autophagy; Non-structural protein 6; mTOR signalling; Host immunity evasion; Viral survival…”
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The Molecular Mechanisms Of Rapamycininduced Autophagy And Apoptosis In T-47d Breast Carcinoma Cells by Moad, Ahmed Ismail Hassan

“…As a strategy, rapamycin, a known inhibitor of mTOR, was used as an autophagy inducer and 3-methyladenine (3MA) as a classical inhibitor of autophagy. …”
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Combinatorial application of tocotrienols and chemotherapeutic drugs enhances apoptosis and autophagy in colorectal cancer cells by Tham, Shiau Ying

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Liver oxidative stress, apoptosis, and autophagy are increased in a mouse model of iron overload by Chua, A., Domenichini, Alice, Delima, R., Elsegood, C., Olynyk, J., Trinder, D.

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