Search Results - "animal testing"

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    The need for regulating animal testing: a comparative study between Malaysia and United Kingdom / Nur Farhana Abdul Latiff … [et al.] by Abdul Latiff, Nur Farhana, Hussein, Athari Faris Ammerry, Ishak, Zairan, Khalip, Abdul Hakim Hissobri

    Published 2011
    “…This research covers law relating to legal protection of animals welfare precisely on animal testing in Malaysia with comparison to United Kingdom. …”
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    Correlations between 3D animation test score, spatial ability and computer experiences amongst multimedia major university students / Sharkawi Che Din by Che Din, Sharkawi

    Published 2013
    “…Specifically the study attempted, 1) to investigate the correlation between Spatial Rotation test score and students’ performance in 3D Computer Animation test score among multimedia major undergraduate students, 2) to investigate the correlation between Spatial Visualization test score and students’ performance in 3D Computer Animation test score among multimedia major undergraduate students, 3) to investigate the correlation between Computer Understanding and Experience Scale (CUE) and performance in 3D Computer Animation course among multimedia major undergraduate students, 4) to determine whether Spatial Ability is the possible predictors of successful performance of 3D Computer Animation course among multimedia major undergraduate students and, 5) to examine significant differences between Spatial Ability test score and a CUE test score based on demographics with their performance in 3D Computer Animation……”
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    Correlations between 3D animation test score, spatial ability and computer experiences amongst multimedia major university students / Sharkawi Che Din by Che Din, Sharkawi

    Published 2013
    “…The coefficient of determination R2 of the Spatial Ability showed 47.4% of the variance in the 3D Computer Animation test score.…”
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    Legal analysis of the Malaysian Animals Act 1953 (revised 2006) in regard to animal testing: with special reference to the legal position in the United Kingdom / Afiqah Najiha Mahadi … [et al.] by Mahadi, Afiqah Najiha, Roszamman, Nur Anees Syafwah, Hassan, Farah Syahirah, Azmi, Nik Zahira

    Published 2014
    “…Comparison between these two countries is also made so that it will give a clearer view that Malaysia is still lacking in regulations when it comes to animal testing despite the existence of the Animals Act 1953 (Revised 2006). …”
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    Toxicity studies of natural product in vero cells using impedance monitoring by Hamdan, Taufik Hakim, Mansor, Ahmad Fairuzabadi, Abbas, Phirdaous, Nordin, Anis Nurashikin, Hashim, Yumi Zuhanis Has-Yun

    Published 2017
    “…Toxicity studies typically use animal testing to predict the harmfulness of a particular substance to human health. …”
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    Toxicity and metabolism of layered double hydroxide intercalated with levodopa in a Parkinson's disease model by Kura, Aminu Umar, Mohd Ain, Nooraini, Hussein, Mohd Zobir, Fakurazi, Sharida, Hussein-Al-Ali, Samer Hasan

    Published 2014
    “…Due to growing concern over animal welfare and the expense of in vivo experiments both the public and the government are interested to find alternatives to animal testing. The toxicity potential of zinc aluminum layered hydroxide (ZAL) nanocomposite containing anti-Parkinsonian agent may be determined using a PC 12 cell model. …”
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    Barbeque with air ventilation system by Wan Nur Amira Shafikah, Wan Mohd Fazli

    Published 2018
    “…The main objective was to segment to improve the heat transfer performance of conventional charcoal because if heat directly touch to charcoal Animal testing has shown exposure to high levels of chemicals such as these is linked with cancer, Combusting wood, gas, or charcoal emits chemicals known as Polycyclic Aromatic Hydrocarbons. …”
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    Faith and Finance: Multicultural Banks Versus Islamic Banks by Hasan, Aznan, Kalair, Omar

    Published 2010
    “…The Dow Jones Dharma fund is based on Dharmic principals found in Buddhist and Hindu scriptures where such things as animal testing are not permitted. A multicultural bank would avail to the multicultural financial needs of society and be inclusive of Islamic finance. …”
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    Development of biorelevant simulated salivary fluids for application in dissolution testing by Gittings, Sally

    Published 2017
    “…This provides a robust analytical approach circumventing the expense and ethical challenges associated with human taste testing panels or animal testing. To achieve taste masking, drug release should be below the bitterness threshold concentration of the API. …”
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    Defining in vivo dose-response curves for kidney DNA adduct formation of aristolochic acid I in rat, mouse and human by an in vitro and physiologically based kinetic modeling appro... by Abdullah, Rozaini, Wesseling, Sebastiaan, Spenkelink, Bert, Louisse, Jochem, Punt, Ans, Rietjens, Ivonne M. C. M.

    Published 2020
    “…It is concluded that the combined in vitro PBK modeling approach provides a novel way to define in vivo dose-response curves for kidney DNA adduct formation in rat, mouse and human and contributes to the reduction, refinement and replacement of animal testing.…”
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    Integrated strategy for the assessment of kidney toxicity: the case of aristolochic acids by Abdullah, Rozaini

    Published 2017
    “…This PhD thesis aimed to provide additional evidence to demonstrate the potential of an integrated testing strategy using in vitro assays with physiologically based kinetic (PBK) modeling based-reverse dosimetry to predict in vivo toxicity without animal testing. Kidney toxicity was chosen as the toxicity endpoint and aristolochic acids (AAs) were selected as model chemicals. …”
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    An evaluation of the neurotoxicity of pesticides and alcohol using human neuroblastoma cells and human progenitor cortical neural stem cells by Wijesekara Mudiyanselage, Anusha Udayangani Kumari Manike Wijesekara

    Published 2021
    “…The cytotoxic responses are dependent not only on the concentration and duration, but also on the developmental stage. hNPC and SH-SY5Y neuroblastoma cells provided in-vitro model systems for the better understanding of cellular and molecular mechanisms involved in development neurotoxicity studies and can be regarded as complementary to animal testing in a cost and time effective manner.…”
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    Development of biomimetic platforms to investigate the influence of the extra-cellular environment on immunological responses by Donaldson, Amy Rose

    Published 2017
    “…An attempt was made at utilising the ECM platform to investigate immune responses to chemical sensitisers to address the requirement for in vitro alternatives to replace current animal testing methods. In this work, innate and adaptive immune responses to sensitisers were detected using the ECM platform. …”
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    Acute and Subchronic Toxicity Study of Euphorbia hirta L. Methanol Extract in Rats by Kwan, Yuet Ping, Ibrahim, Darah, Yeng, Chen, Subramaniam, Sreeramanan, Sreenivasan, Sasidharan

    Published 2013
    “…The extract at a single dose of 5000mg/kg did not produce treatment related signs of toxicity or mortality in any of the animals tested during the 14-day observation period. Therefore, the LD 50 of this plant was estimated to be more than 5000mg/kg. …”
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    Transcriptome and toxin family analysis of the paralysis tick, Ixodes holocyclus by Rodriguez-Valle, M., Moolhuijzen, Paula, Barrero, R., Ong, C., Busch, G., Karbanowicz, T., Booth, M., Clark, R., Koehbach, J., Ijaz, H., Broady, K., Agnew, K., Knowles, A., Bellgard, M., Tabor, A.

    Published 2017
    “…They induced a powerful paralysis in neonatal mice, particularly HT4 which produced rapid and strong respiratory distress in all animals tested. This is the first known genomic database developed for the Australian paralysis tick. …”
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    Antinociceptive effect of Momordica charantia flesh aqueous extract in mice by Yusob, Siti Aminah, Makhtar, Nor 'Adilah, Shaik Mossadeq, Wan Mastura

    Published 2012
    “…In addition, results from the Rotarod performance test showed no significant difference between the control and treatment group (300 mg/kg body weight), suggesting that the extract did not produce apparent motor impairment in all the animals tested. Together, the present data suggests that MCA was effective against pain at the peripheral level most probably through the inhibition of cyclooxygenase (COX) and/or lipooxygenase (LOX) and other inflammatory mediators. …”
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