Search Results - "Wnt signaling pathway"

The Wnt signaling pathways and cell adhesion by Amin, N., Vincan, Elizabeth

“…It is well known that the Wnt signaling pathways affect adhesion and migration via downstream effectors. …”
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Wnt Signaling Pathway Related Genes In Hepatocellular Carcinoma by Ban, Kechen

“…In recent years, the evidence that the Wnt signaling pathway may play a crucial role in the hepatocarcinogenesis represents a major breakthrough. …”
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Wnt-signalling pathways and microRNAs network in carcinogenesis: experimental and bioinformatics approaches by Onyido, Emenike K., Sweeney, Eloise, Nateri, Abdolrahman Shams

“…Furthermore, the fundamental understanding of miRNAmediated regulation of Wnt-signalling pathway and vice versa has been significantly improved by high-throughput genomics and bioinformatics technologies. …”
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Study On The Involvement Of Wif-1 In Oral Carcinogenesis Via Egfr And Wnt Signaling Pathways by Chow , Tan Wei

“…WNT inhibitory factor 1 (WIF-1) is a physiological inhibitor in WNT signaling pathway via its WIF domain. The function of EGF-like domain in WIF-1 remains unclear. …”
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The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression by Vincan, Elizabeth, Barker, N.

“…The potential to effectively target EMT and MET processes at the plasma membrane via the upstream components of the Wnt signalling pathway offers new hope for anti-cancer therapy. © 2008 Springer Science+Business Media B.V.…”
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Implications of the WNT Signalling Pathway for Adipose-derived Mesenchymal Stem Cells in a Breast Tumour Environment by Visweswaran, Malini

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Brewers’ rice induces apoptosis in azoxymethane-induced colon carcinogenesis in rats via suppression of cell proliferation and the Wnt signaling pathway by Tan, Bee Ling, Mohd Esa, Norhaizan, Rahman, Heshu Sulaiman, Hamzah, Hazilawati, Karim, Roselina

“…Conclusions: Taken together, our data suggested that brewers' rice can inhibit cell proliferation, induce apoptosis, and suppress COX-2 and β-catenin expression via the Wnt signaling pathway and holds great promise in the field of chemoprevention as a dietary agent.…”
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Flaxseed extract and its effect on wnt signaling pathway in the osteogenic differentiation potential of stem cells from human exfoliated deciduous teeth (shed). by Mokhtar@Makhtar, Khairani Idah, Mustafa Al-Ahmad, Basma Ezzat, Lestari, Widya, Arief Ichwan, Solachuddin Jauhari, Darnis, Deny Susanti, Nordin, Nur Sazwi, Thirumulu Ponnuraj, Kannan, Ahmad, Azlina

“…Flaxseed extract might block the effect of DKK1 inhibitor thus proposing flaxseed to act as natural-based medication for disease of bone development related to abnormality of WNT signaling pathway.…”
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Treatment of colorectal cancer cells with nanocarrier encap-sulated camptothecin reveals histone modifier genes in the Wnt signaling pathway as important molecular cues for cancer targeting by Aisha Farhana, Koh, Avin Ee Hwan, Kothandan, Sangeetha, Alsrhani, Abdullah, Mok, Pooi Ling, Subbiah, Suresh Kumar

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The roles of WNT1 and DKK1 during in vitro neural differentiation of mouse embryonic stem cell lines by Gao, Liyang

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Swap70b is required for convergent and extension cell movement during zebrafish gastrulation linking Wnt11 signalling and RhoA effector function by Xu, Xiaoou, Shuen, Wai Ho, Chen, Chen, Goudevenou, Katerina, Jones, Peter, Sablitzky, Fred

Subjects: “…Swap70; Guanine nucleotide exchange factor; Convergent and extension cell movement; Gastrulation; Wnt11; Non-canonical Wnt signalling pathway; Def6…”
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The role of the cysteine-rich domain and netrin-like domain of secreted frizzled-related protein 4 in angiogenesis inhibition in vitro by Longman, D., Arfuso, F., Viola, H., Hool, L., Dharmarajan, Arunasalam

“…Classically, sFRP4 antagonizes the canonical Wnt signaling pathway, resulting in decreased cellular proliferation and increased apoptosis. …”
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Effects of silencing dishevelled 1, 2 and 3 mRNA expression on MDA-MB-231 cell migration and invasion using siRNAs by Khoo, Samuel Leon Juan

“…The Wnt signalling pathway plays an important role in embryonic development, generation of cell polarity and specification. …”
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Wnt Signaling Regulation of Tissue Architecture (EMT and MET) and Morphogenesis: Consequences for Colorectal and Liver Cancer by Fifis, T., Tran, B., Schwab, R., Johanson, T., Warner, N., Barker, N., Vincan, Elizabeth

“…The different branches of the Wnt signaling pathway were first characterized in developmental contexts, but in recent times, each branch has been implicated in tumor growth and progression. …”
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Water extract of brewers' rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling... by Tan, Bee Ling, Mohd Esa, Norhaizan, Ky, Huynh, Rahman, Heshu Sulaiman, Yeap, Swee Keong, Hamzah, Hazilawati, Karim, Roselina

“…Methods: The mRNA levels of several upstream-related genes in the Wnt signaling pathway in HT-29 cells treated with WBR were determined by quantitative real-time PCR analyses. …”
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Extracellular matrix (ECM) activates β-catenin signaling in uterine fibroids by Ko, Y., Jamaluddin, M., Adebayo, M., Bajwa, P., Scott, R., Dharmarajan, Arunasalam, Nahar, P., Tanwar, P.

“…We performed Sanger sequencing to define the MED12 mutational status of fibroids and normal myometrium samples. qPCR arrays were carried out to determine the status of the WNT signaling pathway in MED12-mutated and MED12-wild-type fibroids. …”
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The Effects of Combination Treatment Using Phenoxodiol and Docetaxel, and Phenoxodiol and Secreted Frizzled-related Protein 4 on Prostate Cancer Cell Lines by Mahoney, S., Arfuso, Frank, Millward, M., Dharmarajan, Arunasalam

“…This attenuation is associated with the prevention of cells from entering the G2/M phase of the cell cycle where docetaxel is functional in damaging the spindle fibers, and potentially due to p21WAF1 mediated cell survival after docetaxel treatment.We also investigated the use of the Wnt signaling pathway antagonist secreted frizzled-related protein 4 (sFRP4) to increase the effectiveness of phenoxodiol treatment. …”
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Zerumbone and small interference RNA induced apoptosis in MCF-7 cell and mammary gland tumor via β-catenin protein inhibition by Fadl, Safa Abd Elfatah Amin

“…Among these is the Wnt/β-catenin pathway, of which β-catenin is one of the main oncogenes of the Wnt signaling pathway implicated in the adhesion of cancer and non-cancer cells. …”
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Differential effects of dishevelled 2 and 3 on TCF/ LEF- mediated transcriptional activation in wnt-3atreated breast cancer cell line MDA-MB-231 by Khoo, Samuel Leon Juan, Yip, Wai Kien, Seow, Heng Fong

“…Background: Dishevelled (Dvl) proteins are central mediators of the Wnt signalling pathway. Previous studies have shown that Dvl1, 2 and 3 can differentially mediate the Wnt signalling pathway and act at different points in the signalling cascade depending on the cell lines used. …”
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Characterization Of Cal 27 Oral Squamous Carcinoma Cell Line As A Model For Cancer Stem Cell Study by Chai, Yuan Lin

“…In addition to that, involvement of cell adhesion and epithelial-mesenchymal transition (EMT), together with Wnt signaling pathway were investigated. As for the results, elongation of CAL 27-O cells (CAL 27 cells from 6th passage onwards) from CAL 27-Y cells (CAL 27 cells below 6th passage) were found to be associated with enhanced invasive and metastatic capability, greater resistance to treatment, reversal of phenotype characterizing epithelial cells, besides enhanced proliferation. …”
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