Search Results - "VAX"

Immunogenicity study of dna vaccine and dna vaccine carrier expressing vp1 of enterovirus 71 in the prime boost vaccination strategy by Nur Ayuni, Kadir

“…Thus our group have exploring the development of a candidate vaccine involving the construction of a synthetic VP1 gene of EV71 fused to a ubiquitin (UbGR) gene and cloned into a DNA vaccine vector with a strong eukaryotic promoter known as pVAX1, to create the candidate DNA vaccine pVaxUbVP1. …”
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Recombinant salmonella typhi ty21a as vaccine candidate against tuberculosis by Badrul Syam, Mat Zainuddin

“…However, the heterologous primeboost vaccination using pVaxVaclll followed by rSTvaciii(M2) induced lower IFNy production compared to homologous rSTvaciii(M2) or pVaxVaclll vaccination. …”
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Development of Salmonella-based DNA vaccine against respiratory syncytial virus. by Suhaimi, Siti Syazani

“…Therefore, firstly the RSV G epitope regions including residues 125-226 was cloned along with the CTB gene into pVAX1, a mammalian expression vector, resulting a DNA vaccine vector designated as pVAX1-CTB/G. …”
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Development of a Deoxyribonucleic Acid Vaccine Against Enterovirus 71 by Wong, Siew Tung

“…The pVAX1 vector that was successfully cloned with the VP1 gene from each of the isolate (S2/86/1 and 410/4) in the correct orientation and in-frame, were designated as pVAX1/VP1-S and pVAX1/VP1-4,respectively.The DNA vaccine constructs with the VP1 gene were shown to be expressed in a cell-free in vitro expression system. …”
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Immunization with plasmid DNA expressing Heat Shock Protein 40 confers prophylactic protection against chronic Toxoplasma gondii infection in Kunming mice by Li, Zhong-Yuan, Lu, Jing, Zhang, Nian-Zhang, Elsheikha, Hany M., Hou, Jun-Ling, Guo, Hai-Ting, Zhu, Xing-Quan

“…This immunization regimen significantly reduced parasite cyst burden in pVAX1-HSP40-immunized mice (1871.9 ± 142.3) compared with control mouse groups immunized with pVAX1 (3479.2 ± 204.4), phosphate buffered saline (3024.4 ± 212.8), or left untreated (3275.0 ± 179.8) as healthy controls (p < 0.01). …”
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In vivo evaluation of microencapsulated bicistronic plasmid DNA vaccine against Vibrio cholerae by Ahmad Zamri, Najwa

“…Fifteen female rabbits were used in this study and divided into five groups: (1) Mock-infected control (negative control); (2) Empty alginate microsphere (non-vaccinated); Alginate microspheres encapsulating (3) pVAX-ctxB; (4) pVAX-tcpA; and (5) pVAX-ctxB-tcpA. …”
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Oral cholera vaccine by Rosli, Rozita, Shamsudin, Mariana Nor, Abdullah, Syahrilnizam, Nograles, Nadine, Hanafi, Aimi Melati

“…The present invention provides s DNA plasmid pVAX1 comprising coding sequences of the Vibrio cholerae genes ctxB, optionally encapsulated in alginate or cellulose acetate phthalate microspheres. …”
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Oral immunization with cholera DNA vaccine employing microencapsulation delivery system by Nograles, Nadine Hayudini

“…Test animals and control groups were immunized with pVAX-ctxB and/or pVAX-tcpA encapsulated within alginate microspheres. …”
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Quantitative genome-wide methylation analysis of high-grade non-muscle invasive bladder cancer by Kitchen, Mark O., Bryan, Richard T., Emes, Richard D., Glossop, John R., Luscombe, Christopher, Cheng, K.K., Zeegers, Maurice P., James, Nicholas D., Devall, Adam J., Mein, Charles A., Gommersall, Lyndon, Fryer, Anthony A., Farrell, William E.

“…These analyses revealed significantly higher methylation frequencies in high-grade tumours relative to low-intermediate-grade tumours for the ATP5G2, IRX1 and VAX2 genes (p<0.05), and similarly significant increases in mean levels of methylation in high-grade tumours for the ATP5G2, VAX2, INSRR, PRDM14, VSX1, TFAP2b, PRRX1, and HIST1H4F genes (p<0.05). …”
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Using automated text messages to monitor adverse events following immunisation in general practice by Leeb, A., Regan, Annette, Peters, I., Leeb, C., Leeb, G., Effler, P.

“…Objective: To assess the performance of SmartVax, a prototypic active monitoring system for adverse events following immunisation (AEFI) using short message service (SMS) text messages and clinical data extracted from commercially available medical practice management software. …”
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Immunogenicity of recombinant HS ABA392 DNA vaccine against Haemorrhagic septicaemia in animal model / Shamini Chelliah by Shamini , Chelliah

“…In this study, the targeted gene fragment of ABA392 was sub-cloned into a DNA expression vector pVAX1 and named as pVAX1-ABA392. The new recombinant vaccine was stable and expressed via intramuscular. …”
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Immunoprotection by recombinant ABA392 vaccines against Pasteurella multocida mediated haemorrhagic septicaemia / Kang Tzin Lim by Kang , Tzin Lim

“…The aim of the study was to investigate the efficacy of the recombinant protein vaccine, ABA392/pET-30a and DNA vaccine, ABA392/pVAX1 against the P. multocida B:2 infection via intranasal inoculation by targeting the mucosal immunity. …”
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Effects of alum and addavax on immune responses and protection induced by ectodomain of influenza M2 protein displayed on nodavirus capsid by Ong, Hui Kian

“…Therefore, the objective of this study was to investigate the effects of two adjuvants, Alum and AddaVax on the immune responses and protection elicited by NvC-M2ex3 in BALB/c mice. …”
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Real-time safety surveillance of seasonal influenza vaccines in children, Australia, 2015 by Pillsbury, A., Cashman, P., Leeb, A., Regan, Annette, Westphal, D., Snelling, T., Blyth, C., Crawford, N., Wood, N., Macartney, K.

“…Increased febrile reactions in Australian children from one influenza vaccine brand in 2010 diminished confidence in influenza immunisation, highlighting the need for improved vaccine safety surveillance. AusVaxSafety, a national vaccine safety surveillance system collected adverse events in young children for 2015 influenza vaccine brands in real time through parent/carer reports via SMS/email. …”
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Active surveillance of 2017 seasonal influenza vaccine safety: An observational cohort study of individuals aged 6 months and older in Australia by Pillsbury, A., Glover, C., Jacoby, P., Quinn, H., Fathima, P., Cashman, P., Leeb, A., Blyth, C., Gold, M., Snelling, Thomas, Macartney, K.

“…Conclusions Novel, postmarketing AusVaxSafety surveillance demonstrated comparable and expected safety outcomes for the 2017 quadrivalent inactivated influenza vaccine brands used in Australia. …”
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Evaluating And Testing Of A Potential Dna Vaccine Against Vibrio Cholerae by Moh’d Hamadneh, Lama Abdel Qader

“…Next, 4 groups of mice were intramuscularly injected with either the pVax/ctxB vaccine construct or pVaxl as the negative control. …”
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In Vitro Expression of Filarial SXPI Gene for the Development of a Nucleic Acid Based Vaccine by Abd. Majid, Roslaini

“…The presence of SXPl gene in - both vectors were validated by polymerase chain reaction (PCR), restriction enzymes analysis (RE) and finally by automated sequencing. The cloned SXPl in pVAX was designated as pVAXISXP1. The plasmid bearing SXPI gene was transfected into two types of animal cell lines (COS-7 and CHO) using Polyfect Transfection Reagent (Qiagen). …”
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Construction of dna vaccine expressing msp-1c of plasmodium falciparum by Noraini, Mat Yunus

“…The MSP-1C fragment was ligated into pVAX1, a plasmid vector that is designed for use in the development of DNA vaccines. …”
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Virus-like particles of nodavirus displaying the receptor binding domain of SARS-CoV-2 spike protein: a potential VLP-based COVID-19 vaccine by Kumar, Kiven, Tan, Wen Siang, Arshad, Siti Suri, Ho, Kok Lian

“…Immunization of BALB/c mice with the virus-like particles (VLPs) self-assembled from the recombinant CP showed that, with AddaVax as an adjuvant, a significantly high level of humoral response was elicited. …”
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New variants of poly(beta amino esters) to enhance delivery of nucleic acid medicines by Bayraktutan, Hulya

“…The successful safety and efficacy demonstration of Moderna's SpikeVax and BioNTech-Pfizer's Comirnaty mRNA-based COVID-19 vaccines has greatly accelerated the field, with numerous nucleic acid vaccines and therapeutics now in clinical trials. …”
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