Search Results - "TNFα"
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Trichostrongylus colubriformis extract upregulates TNF-α receptor expression and enhances TNF-α sensitivity of L929 cells
Published 2000“…Interestingly, the increase of both TNF-α sensitivity and proliferation of treated L929 cells correlated with an upregulation in expression of TNF-α p55 and p75 receptors.…”
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Cryptotanshinone inhibits TNF-α-induced early atherogenic events in vitro
Published 2016“…However, the anti-atherogenic effects of CTS, particularly on tumor necrosis factor-α (TNF-α)-induced endothelial cell activation, are still unclear. …”
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Inhibition of TNF-α protects in vitro brain barrier from ischaemic damage
Published 2015Subjects: “…TNF-α; Ischaemic injury; Cerebral barrier; In vitro model of BBB; NADPH oxidase; MMP…”
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Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis
Published 2014“…We further demonstrate that TNFα-induced apoptosis leads to caspase-8-dependent PAR-4-cleavage followed by nuclear accumulation of the C-terminal PAR-4 (132-340) fragment, which then induces apoptosis. …”
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IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development
Published 2017“…Co-incubation of differentiating myoblasts with rIL-15 and rTNFα, limited the reduction in MTT and nuclear fusion index (NFI) associated with rTNFα stimulation alone. …”
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NADPH oxidase mediates TNF-α-evoked in vitro brain barrier dysfunction: roles of apoptosis and time
Published 2014Subjects: “…TNF-α; Blood–brain barrier; NADPH oxidase; MMP; Cytoskeleton…”
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PINX1 and TERT are required for TNF-α-induced airway smooth muscle chemokine gene expression
Published 2018“…Telomerase inhibitors and telomerase small interfering RNA (siRNA) reduced TNF-α-induced chemokine expression in ASM cells. …”
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Barrier protective effect of asiatic acid in TNF-α-induced activation of human aortic endothelial cells
Published 2016“…However, asiatic acid did not inhibit TNF-α-induced increased monocyte adhesion and migration. …”
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Barrier protective effects of asiatic acid in TNF-α-induced activation of human aortic endothelial cells
Published 2016“…However, asiatic acid did not inhibit TNF-α-induced increased monocyte adhesion and migration. …”
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Photocrosslinkable gelatin hydrogels modulate the production of the major pro-inflammatory cytokine, TNF-α, by human mononuclear cells
Published 2018“…Using lipopolysaccharide to stimulate a pro-inflammatory immune response, we found tumour necrosis factor-α (TNF-α) expression was suppressed in GelMA culture conditions. …”
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Effects of synthetic 2, 4, 6-trihydroxy-3-geranylacetophenone upon TNF-α-induced epithelial dysfunction
Published 2016“…A549 cell was induced with tumor necrosis factor alpha (TNF-α) 10ng/mL and co-treated with different concentration of tHGA (50μM, 12μM, 3μM) and Dexamethsone 10 μM act as drug control group. …”
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The effect of steeping robusta coffee beans on monocytes: Expression of IL-1β and TNF-α against Streptococcus mutans
Published 2019“…Adhesion, IL–1β, TNF–α are components that affect in inflammation. …”
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Inhibitory activity of Ficus deltoidea var. trengganuensis Aqueous extract on lipopolysaccharide-induced TNF-α production from microglia
Published 2017“…Objective: To explore the effect of Ficus deltoidea (FD) aqueous extracts on the release of tumor necrosis factor-α (TNF-α), the expression of CD40, and the morphology of microglial cells in lipopolysaccharide- (LPS-) activated BV2 cells. …”
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Δ9-tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB2 receptors
Published 2016“…The aim of this study was to investigate the effects of THC on bronchial epithelial cell permeability after exposure to the pro-inflammatory cytokine, TNFα. Calu-3 bronchial epithelial cells were cultured at air-liquid interface. …”
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The protective effects of a synthetic geranyl acetophenone in a cellular model of TNF-α-induced pulmonary epithelial barrier dysfunction
Published 2018“…Gene and protein expression were analyzed by RT-PCR and Western blotting or ELISA, respectively. tHGA suppressed leukocyte adhesion to TNF-α-induced epithelium and reduced MCP-1 and ICAM-1 gene expression and secretion. tHGA also increased TEER readings, reduced epithelial permeability and enhanced expression of junctional complex molecules (zona occludens-1, occludin and E-cadherin) in TNF-α-induced cells. …”
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Association of TNF-α G308A gene polymorphism in essential hypertensive patients without type 2 diabetes mellitus
Published 2015“…This study aims to investigate the effects of tumor necrosis factor alpha (TNF-α) G308A gene polymorphism on essential hypertension (EHT) with or without type 2 diabetes mellitus (T2DM). …”
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Suppression of PKC-α attenuates TNF-α-evoked cerebral barrier breakdown via regulations of MMP-2 and plasminogen–plasmin system
Published 2016Subjects: “…TNF-α; blood-brain barrier; PKC-α; PPS components; MMP-2; claudin-5; apoptosis; stress fibres…”
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