Search Results - "TNFα"

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    Trichostrongylus colubriformis extract upregulates TNF-α receptor expression and enhances TNF-α sensitivity of L929 cells by Riffkin, M.C., Seow, H.-F., Wood, P.R., Brown, L.E.

    Published 2000
    “…Interestingly, the increase of both TNF-α sensitivity and proliferation of treated L929 cells correlated with an upregulation in expression of TNF-α p55 and p75 receptors.…”
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    Cryptotanshinone inhibits TNF-α-induced early atherogenic events in vitro by Ahmad, Zuraini, Chin, Theng Ng, Lai, Yen Fong, Abu Bakar, Nurul Ain, Mohd Hussain, Nor Hayuti, Kok, Pian Ang, Cheng , Gwendoline Lian Ee, , Muhammad Nazrul Hakim

    Published 2016
    “…However, the anti-atherogenic effects of CTS, particularly on tumor necrosis factor-α (TNF-α)-induced endothelial cell activation, are still unclear. …”
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    Inhibition of TNF-α protects in vitro brain barrier from ischaemic damage by Abdullah, Zuraidah, Rakkar, Kamini, Bath, Philip M.W., Bayraktutan, Ulvi

    Published 2015
    Subjects: “…TNF-α; Ischaemic injury; Cerebral barrier; In vitro model of BBB; NADPH oxidase; MMP…”
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    Caspase-8-mediated PAR-4 cleavage is required for TNFα-induced apoptosis by Treude, Fabian, Kappes, Ferdinand, Fahrenkamp, Dirk, Müller-Newen, Gerhard, Dajas-Bailador, Federico, Krämer, Oliver H., Lüscher, Bernhard, Hartkamp, Jörg

    Published 2014
    “…We further demonstrate that TNFα-induced apoptosis leads to caspase-8-dependent PAR-4-cleavage followed by nuclear accumulation of the C-terminal PAR-4 (132-340) fragment, which then induces apoptosis. …”
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    IL-15 promotes human myogenesis and mitigates the detrimental effects of TNFα on myotube development by O’Leary, Mary F., Wallace, Graham R., Bennett, Andrew J., Tsintzas, Kostas, Jones, Simon W.

    Published 2017
    “…Co-incubation of differentiating myoblasts with rIL-15 and rTNFα, limited the reduction in MTT and nuclear fusion index (NFI) associated with rTNFα stimulation alone. …”
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    NADPH oxidase mediates TNF-α-evoked in vitro brain barrier dysfunction: roles of apoptosis and time by Abdullah, Zuraidah, Bayraktutan, Ulvi

    Published 2014
    Subjects: “…TNF-α; Blood–brain barrier; NADPH oxidase; MMP; Cytoskeleton…”
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    PINX1 and TERT are required for TNF-α-induced airway smooth muscle chemokine gene expression by Deacon, Karl, Knox, Alan J.

    Published 2018
    “…Telomerase inhibitors and telomerase small interfering RNA (siRNA) reduced TNF-α-induced chemokine expression in ASM cells. …”
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    Effects of synthetic 2, 4, 6-trihydroxy-3-geranylacetophenone upon TNF-α-induced epithelial dysfunction by Sim, Tee Yee

    Published 2016
    “…A549 cell was induced with tumor necrosis factor alpha (TNF-α) 10ng/mL and co-treated with different concentration of tHGA (50μM, 12μM, 3μM) and Dexamethsone 10 μM act as drug control group. …”
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    Inhibitory activity of Ficus deltoidea var. trengganuensis Aqueous extract on lipopolysaccharide-induced TNF-α production from microglia by Wang, Huiling, Vidyadaran, Sharmili, Mohd Moklas, Mohamad Aris, Baharuldin, Mohamad Taufik Hidayat

    Published 2017
    “…Objective: To explore the effect of Ficus deltoidea (FD) aqueous extracts on the release of tumor necrosis factor-α (TNF-α), the expression of CD40, and the morphology of microglial cells in lipopolysaccharide- (LPS-) activated BV2 cells. …”
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    Δ9-tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB2 receptors by Shang, Valerie C.M., Kendall, David A., Roberts, Richard E.

    Published 2016
    “…The aim of this study was to investigate the effects of THC on bronchial epithelial cell permeability after exposure to the pro-inflammatory cytokine, TNFα. Calu-3 bronchial epithelial cells were cultured at air-liquid interface. …”
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    The protective effects of a synthetic geranyl acetophenone in a cellular model of TNF-α-induced pulmonary epithelial barrier dysfunction by Tee, Yee Sim, Harith, Hanis Hazeera, Tham, Chau Ling, Md Hashim, Nur Fariesha, Shaari, Khozirah, Sulaiman, Mohd Roslan, Israf Ali, Daud Ahmad

    Published 2018
    “…Gene and protein expression were analyzed by RT-PCR and Western blotting or ELISA, respectively. tHGA suppressed leukocyte adhesion to TNF-α-induced epithelium and reduced MCP-1 and ICAM-1 gene expression and secretion. tHGA also increased TEER readings, reduced epithelial permeability and enhanced expression of junctional complex molecules (zona occludens-1, occludin and E-cadherin) in TNF-α-induced cells. …”
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    Association of TNF-α G308A gene polymorphism in essential hypertensive patients without type 2 diabetes mellitus by Ghodsian, N., Akhlaghi, M., Ramachandran, V., Heidari, F., Haghvirdizadeh, P., Eshkoor, S. A., Etemad, A., Jamaluddin, J. A., Ismail, Patimah

    Published 2015
    “…This study aims to investigate the effects of tumor necrosis factor alpha (TNF-α) G308A gene polymorphism on essential hypertension (EHT) with or without type 2 diabetes mellitus (T2DM). …”
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    Suppression of PKC-α attenuates TNF-α-evoked cerebral barrier breakdown via regulations of MMP-2 and plasminogen–plasmin system by Abdullah, Zuraidah, Bayraktutan, Ulvi

    Published 2016
    Subjects: “…TNF-α; blood-brain barrier; PKC-α; PPS components; MMP-2; claudin-5; apoptosis; stress fibres…”
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