Search Results - "TDP 43"

Imbalanced expression of polycistronic miRNA in acute myeloid leukemia by Kotaki, Ryutaro, Higuchi, Hiroshi, Ogiya, Daisuke, Katahira, Yasuhiro, Kurosaki, Natsumi, Yukihira, Naoko, Ogata, Jun, Yamamoto, Haruna, Mohamad Alba, Syakira, Azhim, Azran, Kitajima, Tatsuo, Inoue, Shigeaki, Morishita, Kazuhiro, Ono, Koh, Koyama-Nasu, Ryo, Kotani, Ai

“…The expression levels of TDP-43, an RNA-binding protein that has been reported to increase the expression, but inhibits the activity, of miR-1, were not correlated with expression levels of miR-1 in AML cells. …”
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Connecting MicroRNA and autophagy disturbances in Amyotrophic Lateral Sclerosis (ALS) by Foggin, Sophie

“…One such possible target, UNC13A, is associated with the mislocalisation of TDP- 43, seen in almost all ALS cases. Recently, it has been highlighted that ‘direct’ and ‘indirect’ mRNA targets of a miRNA might contribute distinctly to motor neurone dysfunction and we establish a pipeline to determine potential ‘direct’ and ‘indirect’ mRNA targets of a miRNA using mRNA sequencing data. …”
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