Search Results - "T cell immunity"
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Therapeutic prospects of extracellular vesicles in cancer treatment
Published 2018Subjects: “…extracellular vesicles; Tumour microenvironment; Tumour Cells; Immune Cells; Stromal cells; Vaccination; Cancer Therapy…”
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Insights into innate and adaptive immune responses in vaccine development against EV-A71
Published 2019“…In particular, the role of innate and T cell immunity during HFMD infection remains unclear and there is evidence suggesting the importance of CD4+ and CD8+ T cells for protective immunity. …”
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Natural T cell–mediated protection against seasonal and pandemic Influenza: results of the Flu Watch cohort study
Published 2015“…Animal and human challenge studies and observational studies suggest T cells protect against disease among those infected, but the impact of T-cell immunity at the population level is unknown. …”
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Development Of HSPX Vaccine Against Latent Tuberculosis Using Adjuvant-Dependent T-Helper Alternating Peptide Strategy
Published 2020“…Results indicated that recombinant HspX protein was proven to be immunogenic in C57BL/6 mice, showing an improved antigen-specific IgG1 and IgG2a antibody secretion and memory CD8+ T-cell immunity under stimulation of CASAC adjuvant.…”
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Immediate early protein of equid herpesvirus type 1 as a target for cytotoxic T-lymphocytes in the thoroughbred horse
Published 2014“…Thus, the IE protein is an attractive candidate molecule for future studies of T-cell immunity to EHV-1 in the horse.…”
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IL-2/CD40-activated macrophages rescue age and tumor-induced T cell dysfunction in elderly mice
Published 2014“…In contrast, tumor-exposed, IL-2/CD40-stimulated macrophages rescued elderly-derived T cell IFN-γ production, suggesting that IL-2/CD40-activated macrophages could rescue T cell immunity in aging hosts.…”
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Immunomodulatory activity of polyphenols derived from Cassia auriculata flowers in aged rats.
Published 2011“…Our results collectively show that polyphenols derived from CA boost T cell immunity by increasing the number of T cells and its sensitivity towards stimulants and decreasing ROS production by neutrophils that could potentially harm multiple biological systems in aged individuals.…”
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Analysis of the QuantiFERON-CMV assay, CMV viraemia and antiviral treatment following solid organ transplantation in Western Australia
Published 2018“…In the solid organ transplant recipients we examined, the prevalence of asymptomatic CMV viraemia was high at 61% but only two patients ultimately developed CMV disease, both of whom had negative QuantiFERON-CMV responses, indicating lack of CMV T-cell immunity. The vast majority (94%) of patients who had spontaneous resolution or stability of asymptomatic CMV viraemia without any antiviral treatment had positive QuantiFERON-CMV responses. …”
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Targeting macrophages rescues age-related immune deficiencies in C57BL/6J geriatric mice
Published 2013“…Therefore, targeting macrophages with IL-2/anti-CD40 antibody may improve innate and T-cell immunity in aging hosts.…”
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Clostridium difficile modulates host innate immunity via toxin-independent and dependent mechanism(s)
Published 2013“…Significant increase in IL-8 suggested potential for neutrophil influx while presence of IL-12, IL-23, IL-1β and IL-6 was indicative of a cytokine milieu that may modulate subsequent T cell immunity. Majority of C. difficile-driven effects on murine bone-marrow-derived dendritic cell (BMDC) activation were toxin-independent; the toxins were however responsible for BMDC inflammasome activation. …”
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Immuno-silent polymer capsules encapsulating nanoparticles for bioimaging applications
Published 2017“…KEYWORDS: PEGylated polymer capsules, M1 and M2 macrophages, dendritic cells, immune response…”
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Efficacy of dendritic cell-based vaccine on acute myeloid leukaemia in a murine model
Published 2013“…Dendritic cells (DCs) are professional antigen presenting cells that able to elicit specific T cell immunity. Their use in immunotherapy is to direct immune response against residual tumour cells and eventually lead to complete tumour eradication. …”
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Characterization of antiviral T cell responses during primary and secondary challenge of laboratory cats with feline infectious peritonitis virus (FIPV)
Published 2019“…Results: Differences in disease outcome provided an opportunity to investigate the role of T cell immunity to FIP determined by T cell subset proliferation after stimulation with different viral antigens. …”
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