Search Results - "RKO"

The role of p-glycoprotein in bacterial attachment to intestinal cells. by Crowe, Andrew

“…The RKO cell line was chosen to provide a cell line with minimal P-gp expression. …”
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An investigation of metastatic colorectal cancer by Asiri, Abutaleb

“…GNAS1 was knocked-down in two CRC cell lines (RKO, and SW620). Gene knockdown was undertaken by transfecting small interfering RNAs into the cells and this was followed by an evaluation of cell proliferation and motility. …”
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A novel Osmium-based compound targets the mitochondria and triggers ROS-dependent apoptosis in colon carcinoma by Maillet, A., Yadav, S., Loo, Y., Sachaphibulkij, K., Pervaiz, Shazib

“…Interestingly, the sensitivity of cell lines to Os was linked to its ability to induce mitochondrial ROS production (HCT116 and RKO) as HT29 and SW620 cell lines that failed to show an increase in ROS were resistant to the death-inducing activity of Os. …”
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Efflux transporters and tight junction expression changes in human gastrointestinal cell lines cultured in defined medium vs serum supplemented medium by Warrier, A., Gunosewoyo, Hendra, Crowe, Andrew

“…© 2018 Aims: Many gastrointestinal cell lines including Caco-2, LS174T and RKO require foetal calf serum (FCS) in culture medium. …”
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In-vitro and in-silico evaluations of heterocyclic-containing diarylpentanoids as Bcl-2 inhibitors against LoVo colorectal cancer cells by Leong, Sze Wei, Chia, Suet Lin, Abas, Faridah, Yusoff, Khatijah

“…In the present study, we investigated the in-vitro anti-cancer potential of six diarylpentanoids against a panel of BRAF- and KRAS-mutated colorectal cancer cell lines including T84, SW620, LoVo, HT29, NCI-H508, RKO, and LS411N cells. Structure-activity relationship study suggested that the insertions of tetrahydro-4H-thiopyran-4-one and brominated phenyl moieties are essential for better cytotoxicity. …”
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