Search Results - "Pharmacogenetics"

Pipeline pharmacogenetics: A novel approach to integrating pharmacogenetics into drug development by Akkari, Patrick, Swanson, T., Crenshaw, D., Grossman, I., Sundseth, S., Burns, D., Roses, A.

“…We describe here the concept of pipeline pharmacogenetics and its application throughout the phases of drug discovery. …”
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Pharmacogenetics, pharmacogenomics and airway disease by Hall, Ian P.

“…This review describes recent advances in pharmacogenetics and pharmacogenomics with regard to airway disease…”
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Pharmacogenetics in cardiovascular disorders: An update on the principal drugs by Predazzi, I., Mango, R., Norata, Giuseppe, Di Daniele, N., Sergi, D., Romeo, F., Novelli, G.

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Pharmacogenetics of beta adrenergic blockers: their clinical significance by Elsayed, Tarek Mohamed Ali

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Phenotypic and pharmacogenetic evaluation of patients with thiazide-induced hyponatremia by Ware, James S., Wain, Louise V., Channavajjhala, Sarath K., Jackson, Victoria E., Edwards, Elizabeth, Lu, Run, Siew, Keith, Jia, Wenjing, Shrine, Nick, Kinnear, Sue, Jalland, Mahli, Henry, Amanda P., Clayton, Jenny, O’Shaughnessy, Kevin M., Tobin, Martin D., Schuster, Victor, Cook, Stuart, Hall, Ian P., Glover, Mark

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Pharmacogenomics and pharmacometabolomics of selective serotonin reuptake inhibitors in patients with depression at hospitals in the Klang Valley, Malaysia by Badamasi, Ibrahim Mohammed

Subjects: “…Pharmacogenetics…”
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The Personalization of Clopidogrel Antiplatelet Therapy: The Role of Integrative Pharmacogenetics and Pharmacometabolomics by Amin, Arwa M., Lim, Sheau Chin, Mohamed Noor, Dzul Azri, SK Abdul Kader, Muhamad Ali, Yuen, Kah Hay, Ibrahim, Baharudin

“…The advantage of pharmacometabolomics is that it does not only predict the response but also provide extensive information on the metabolic pathways implicated with the response. Integrating pharmacogenetics with pharmacometabolomics can give insight on unknown genetic and nongenetic factors associated with the response.This review aimed to review the literature on factors associated with the variable platelets reactivity response to clopidogrel, as well as appraising current methods for the personalization of clopidogrel therapy. …”
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Metabolomics and pharmacogenetics based 5-fluorouracil monitoring in colorectal cancer patients by Zakaria, Bannur, Mohd Zaki, Salleh, Hashim, Hazwanie, Tom, Hennessy, Md Nor, Azmi, MH, Zailani, Prabu, Ramasamy, ZA, Zakaria, Suneet, S, Ngow, Harris Abdullah, Henry, Guy M., Teh, Laykek

“…Keywords: Metabolomics, Pharmacogenetics, Polymorphism, Colorectal cancer (CRC), 5-fluorouracil (5-FU)…”
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Metabolomics and pharmacogenetics based 5-fluorouracil monitoring in colorectal cancer patients by Bannur, Zakaria, Salleh, Mohd Zaki, Hashim, H., Hennessy, Thomas, Azmi, M. N., Zailani, M. H., Ramasamy, P., Zakaria, Zainul Amiruddin, Suneet, S., Abdullah, Harris Ngow, Henry, G., Teh, Lay Kek

“…In addition, the metabolic profiles associated with different genotypes of DPYD and UGT1A1 explains the impact of genetic variation on differential drug responses. Conclusion: Pharmacogenetics and metabolomics profiles are potential platforms for more comprehensive monitoring of patient's disease progress and drug response. …”
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The role of pharmacogenetic variation in metoprolol CYP2D6 genotypes polymorphism by Wan Sulaiman, Wan Mohd. Azizi, Abdul Razak, Tariq, Lay, Kek Teh, Ismail, Rusli

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Can population differences in chemotherapy outcomes be inferred from differences in pharmacogenetic frequencies by Loh, M., Chua, D., Yao, Y., Soo, R., Garrett, K., Zeps, Nikolajs, Platell, C., Minamoto, T., Kawakami, K., Iacopetta, B., Soong, R.

“…Inter-ethnic differences in drug handling and frequencies of pharmacogenetic variants are increasingly being characterized. …”
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Utility of pharmacogenetic testing to optimise antidepressant pharmacotherapy in youth: a narrative literature review by Roberts, B., Cooper, Z., Lu, S., Stanley, S., Majda, Bernadette T., Collins, K.R.L., Gilkes, L., Rodger, J., Akkari, P.A., Hood, S.D.

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A Clinical And Pharmacogenetic Investigation Of Methadone Maintenance Therapy (MMT) In Opiate Dependent Individuals by Mohamad, Nasir

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A pharmacogenetics study on acute pain perception among patents on methadone maintenance therapy (MMT) by Zahari, Zalina

“…The objectives of this study were to investigate the pharmacogenetic factors that influence pain responses in patients on methadone maintenance therapy (MMT) and opioid-naive individuals. …”
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Knowledge, perception and confidence of physicians and pharmacists at IIUM Medical Centre towards pharmacogenetics application in clinical setting by Azmi, Diyana, Ghani, Nazifa Husna, Saadon, Nurul Syahirah, Raja Musa, Puteri Aimi Athirah, Rosmahidi, Rosfatina Farzana, Mohamed Nazar, Nor Ilyani

“…Introduction: The importance of pharmacogenetics practices in hospital settings is to improve the patients’ treatment by maximising the therapeutic outcomes and reduce the adverse effect of the drug. …”
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Benchmarking in silico tools for the functional assessment of DNA variants using a set of strictly pharmacogenetic variants by Chua, Eng Wee, Goh, Chian Siang

“…In this work, we benchmarked the performance of eight prediction methods using a set of strictly pharmacogenetic variants. We first compiled a set of damaging or neutral variants that affected pharmacogenes from two online databases. …”
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The Personalization of Clopidogrel Antiplatelet Therapy in Coronary Artery Disease Patients using Pharmacometabonomics, Pharmacogenetics and Platelets Function Testing by Mostafa, Arwa Mohamed Amin

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Imatinab mesylate treatment in Chronic Myeloid Leukemia (CML)- understanding the fundamental pharmacokinetic and pharmacogenetic mechanisms for variation in response by Ankathil, Ravindran

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Variability in responses of tacrolimus in kidney transplant patients: the use of pharmacogenetics and metabolomics in closing the gaps in clinical practices / Sharina Hamzah by Hamzah, Sharina

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Interpatient variability in tamoxifen respone among breast cancer patient: the use of pharmacogenetics and metabolomics in closing the gaps in clinical practice / Nor Izwani Mohamed by Mohamed, Nor Izwani

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