Search Results - "Mycobacterium tuberculosis"
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Electrochemical immunosensor for detection of Mycobacterium tuberculosis
Published 2018“…A rapid and sensitive sandwich electrochemical immunosensor was developed based on the fabrication of the graphene/polyaniline (GP/PANI) nanocomposite onto screen-printed gold electrode (SPGE) for detection of Mycobacterium tuberculosis (M. tuberculosis) antigen. The chemical bonding and morphology of GP/PANI-modified SPGE were studied by Raman spectroscopy and field enhance scanning electron microscopy-energy dispersive X-ray spectroscopy (FESEM-EDX), respectively. …”
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p-Hydroxybenzoic acid synthesis in mycobacterium tuberculosis
Published 2005“…Glycosylated p-hydroxybenzoic acid methyl esters and structurally related phenolphthiocerol glycolipids are important virulence factors of Mycobacterium tuberculosis. Although both types of molecules are thought to be derived from p-hydroxybenzoic acid, the origin of this putative biosynthetic precursor in mycobacteria remained to be established. …”
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Synthesis of Potential Mycobacterium Tuberculosis InhA Inhibitors
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Kinase Targets for Mycolic Acid Biosynthesis in Mycobacterium tuberculosis.
Published 2018“…Mycolic acids (MAs) are the characteristic, integral building blocks for the mycomembrane belonging to the insidious bacterial pathogen Mycobacterium tuberculosis (M.tb). These C60-C90 long a-alkyl-ß-hydroxylated fatty acids provide protection to the tubercule bacilli against the outside threats, thus allowing its survival, virulence and resistance to the current antibacterial agents. …”
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Indoleamides are active against drug-resistant Mycobacterium tuberculosis
Published 2013“…The emergence of multidrug- and extensively drug-resistant strains of Mycobacterium tuberculosis confounds control efforts, and new drugs with novel molecular targets are desperately needed. …”
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Molecular genotyping of mycobacterium tuberculosis associated with extrapulmonary tuberculosis
Published 2015“…Recent advances in molecular typing provide a robust tool to analyse the heterogeneity of Mycobacterium tuberculosis strains as well as their transmission patterns. …”
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Respiratory microbiome and its susceptibility to Mycobacterium tuberculosis infection
Published 2019“…Although the interest in microbial composition of microbiota in respiratory tracts has recently been increased, the possible relationship between the composition and abundance of microbiota in the ecological niche of human throat with Mycobacterium tuberculosis infection are poorly understood. …”
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Cloning and characterization of mycobacterium tuberculosis katG gene
Published 2005“…katG is tbe sole gene encoding for catalase peroxidase enzyme in Mycobacterium tuberculosis enabling its survival in the host macrophage. …”
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The cloning and chcracterization of mycobacterium tuberculosis katG gene
Published 2005“…TB is caused by an organism called Mycobacterium tuberculosis (MTB) also sometimes called as the tubercle baciJii. …”
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Structure and function of proteins important in Mycobacterium tuberculosis energy metabolism
Published 2009“…Mycobacterium tuberculosis (Mb) is the causative agent of tuberculosis (TB). …”
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Lateral flow immunoassay for naked eye detection of Mycobacterium tuberculosis
Published 2020“…Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. Detection and control of infectious diseases is a major problem, especially in developing countries. …”
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Development of recombinase polymerase amplification assay for the detection of mycobacterium tuberculosis
Published 2022“…In this study, a rapid assay for the detection of Mycobacterium tuberculosis (Mtb) based on the RPA targeting the B9 sequence was developed. …”
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Examining the role of protein structural dynamics in drug resistance in Mycobacterium tuberculosis
Published 2017“…To gain deeper insight into antibiotic-target interactions, the binding of the frontline anti-tuberculosis drug isoniazid (INH) to a target enzyme, InhA, from Mycobacterium tuberculosis was studied using ultrafast two-dimensional infrared (2D-IR) spectroscopy and molecular simulations. …”
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Development Of A Nucleic Acid Amplification Test For The Detection Of Mycobacterium Tuberculosis
Published 2015“…Tuberculosis is one of the common infectious diseases in Malaysia, caused by the airborne pathogen, Mycobacterium tuberculosis. Due to the infectious nature of the disease, diagnostic-based detection of Mycobacterium tuberculosis is vital for effective disease management, surveillance, epidemiological purpose and for the administration of a prompt treatment. …”
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