Search Results - "INKT"

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  1. 1
    The role of invariant natural killer T cells and lipids in the development of allergic sensitisation

    The role of invariant natural killer T cells and lipids in the development of allergic sensitisation by Hopkins, Georgina

    Published 2023
    “…Methods Due to low abundance of iNKT cells in human peripheral blood, iNKT cells were expanded over 14 days by stimulation with the glycolipid, α-Galactosylceramide (α-GalCer), which is a potent activator of iNKT cells. …”
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  2. 2
    Mucosal-associated invariant T cell alterations during the development of human type 1 diabetes

    Mucosal-associated invariant T cell alterations during the development of human type 1 diabetes by Ahmad Mahfuz, Gazali, Schroderus, Anna-Mari, Salonen, Kirsti Näntö, Rintamäki, Reeta, Pihlajamäki, Jussi, Knip, Mikael, Veijola, Riitta, Toppari, Jorma, Ilonen, Jorma, Kinnunen, Tuure

    Published 2020
    “…Methods We analysed the frequency, phenotype and functionality of peripheral bloodMAIT cells, as well as γδ T cells, invariant natural killer T (iNKT) cells and natural killer (NK) cells with flow cytometry in a cross-sectional paediatric cohort (aged 2–15) consisting of 51 children with newly diagnosed type 1 diabetes, 27 autoantibody-positive (AAb+) at-risk children, and 113 healthy control children of similar age and HLA class II background. …”
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  3. 3
    Characterisation of anti-glycan monoclonal antibodies

    Characterisation of anti-glycan monoclonal antibodies by Noble, Philip W.

    Published 2011
    “…This study suggests that the incorporation of tumour glycolipid into liposomes and their immunisation along with the iNKT cell adjuvant α-galactosylceramide, elicits an anti-tumour glycolipid immune response, which can yield IgG mAbs capable of binding a high proportion of ovarian cancers. …”
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