Search Results - "GPCRs"

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  1. 1
    Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias

    Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias by Dijon, Nicola C

    Published 2022
    Subjects: Get full text
  2. 2
    GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors

    GPCRs through the keyhole: the role of protein flexibility in ligand binding to β-adrenoceptors by Emtage, Abigail L., Mistry, Shailesh N., Fischer, Peter M., Kellam, Barrie, Laughton, Charles A.

    Published 2016
    Subjects: “…GPCRs…”
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  3. 3
    Preparation and structural analysis of (±)-cis-ethyl 2-sulfanylidenedecahydro-1,6-naphthyridine-6-carboxylate and (±)-trans-ethyl 2-oxooctahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxylate

    Preparation and structural analysis of (±)-cis-ethyl 2-sulfanylidenedecahydro-1,6-naphthyridine-6-carboxylate and (±)-trans-ethyl 2-oxooctahydro-1H-pyrrolo[3,2-c]pyridine-5-carboxy... by Schwehm, Carolin, Lewis, William, Blake, Alexander J., Kellam, Barrie, Stocks, Michael J.

    Published 2014
    Subjects: “…X-ray crystal structure; privileged structure; bicycle formation; biologically active compounds; NMR evaluation; medicinal chemistry; GPCRs; polycyclic scaffolds…”
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  4. 4
    Investigating cooperativity across adenosine A3 receptor homo- and hetero-oligomers

    Investigating cooperativity across adenosine A3 receptor homo- and hetero-oligomers by Groenewoud, N.J.A.

    Published 2019
    Subjects: “…GPCRs…”
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  5. 5
    Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors

    Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors by van der Westhuizen, Emma T., Spathis, Arthur, Khajehali, Elham, Jörg, Manuela, Mistry, Shailesh N., Capuano, Ben, Tobin, Andrew B., Sexton, Patrick M., Scammells, Peter J., Valant, Celine, Christopoulos, Arthur

    Published 2018
    Subjects: “…Acetylcholine receptors; Allosterism; Alzheimer's Disease; Biased agonism; Cholinergic pharmacology; Cognition; Drug discovery; G protein-coupled receptors (GPCRs); Muscarinic cholinergic receptors; Schizophrenia…”
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