Search Results - "GPCR"

Negative cooperativity across 1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 1-adrenoceptor binding conformation by Gherbi, Karolina, May, Lauren T., Baker, Jillian G., Briddon, Stephen J., Hill, Stephen J.

Subjects: “…dissociation; receptor dimerization; GPCR; allosterism…”
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Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization by Hill, Stephen J., May, Lauren T., Kellam, Barrie, Woolard, Jeanette

Subjects: “…adenosine ; allosterism ; receptor ; GPCR ; dimerization ; biased signalling…”
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Kinetic analysis of antagonist-occupied adenosine-A3 receptors within membrane microdomains of individual cells provides evidence of receptor dimerization and allosterism by Corriden, Ross, Kilpatrick, Laura E., Kellam, Barrie, Briddon, Stephen J., Hill, Stephen J.

Subjects: “…GPCR; dissociation; fluorescence correlation spectroscopy; fluorescent ligand…”
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A monoclonal antibody raised against a thermo-stabilised β1-adrenoceptor interacts with extracellular loop 2 and acts as a negative allosteric modulator of a sub-set of 1- adrenoce... by Soave, Mark, Cseke, Gabriella, Hutchings, Catherine J., Brown, Alastair J.H., Woolard, Jeanette, Hill, Stephen J.

Subjects: “…GPCR; Allosterism; Monoclonal antibody; Extracellular loop 2…”
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Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor by Tuzer, Cemre

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Illuminating the life of the adenosine receptors: development and application of subtype-selective fluorescent probes for the study of the human A1 and A2A adenosine receptors in l... by Comeo, Eleonora

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Determination of the ligand pharmacophore required for secondary conformation activation of the human β1-adrenoceptor by Pinto de Sousa, Emanuel

Subjects: “…G protein-coupled receptors(GPCR); β1-AR ; Alprenolol ; Oxprenolol…”
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Design, Synthesis, and Development of Novel Intracellular Allosteric Modulators of CXC Chemokine Receptor 1 and 2 by Francis, Rhys

Subjects: “…Chemokine GPCR CADD SBDD CXCR1 CXCR2 Homology modelling…”
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Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma by Middlewick, Robert James

Subjects: “…GPCR…”
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Computational and experimental studies of novel β-adrenoceptor ligands by Louison, Keverne

Subjects: “…GPCR…”
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Synthesis and evaluation of the first fluorescent antagonists of the human P2Y2 receptor based on AR-C118925 by Conroy, Sean, Kindon, Nicholas, Glenn, Jacqueline, Stoddart, Leigh A., Lewis, Richard James, Hill, Stephen J., Kellam, Barrie, Stocks, Michael J.

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Monoclonal anti-β1-adrenergic receptor antibodies activate G protein signaling in the absence of β-arrestin recruitment by Hutchings, Catherine J., Cseke, Gabriella, Osborne, Greg, Woolard, Jeanette, Zhukov, Andrei, Koglin, Markus, Jazayeri, Ali, Pandya-Pathak, Jahnavi, Langmead, Christopher J., Hill, Stephen J., Weir, Malcolm, Marshall, Fiona H.

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Chemical and in silico exploration of novel 5-hydroxytryptamine 2A receptor (5-HT2AR) ligands by Damerum, Luke

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Agonist stimulus trafficking by human prostanoid CRTH2 (DP2) receptors. by McArthur Wilson, Richard John

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Activation of the feline umami receptor fT1R1-fT1R3 by linear α-L-dipeptides: an in vitro study by Hernangomez de Alvaro, Carlos Juan

Subjects: “…Umami; cat; peptide; feline; taste; in vitro; in silico; GPCR; T1R1-T1R3; receptor; activation; activity; perception; sensory; pet; Waltham; Mars; Petcare; sensory; food; fluorescence; luminescence; EC50; solubility; pattern; carnivore.…”
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Relaxin-like peptides in male reproduction: a human perspective by Ivell, Richard, Agoulnik, Alexander I., Anand-Ivell, Ravinder

Subjects: “…leucine-rich repeat-containing GPCR 7…”
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