Search Results - "G-protein"

Universal sensors for identifying use-dependent intracellular allosteric modulators of G protein coupled receptors by Farmer, James

Subjects: “…G protein-coupled receptors; Allosteric mechanisms; Allosteric modulators; G protein derived peptidomimetics…”
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Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor by Tuzer, Cemre

Subjects: “…G protein-coupled receptors…”
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Compartmentalised signalling and trafficking of CXCR4 and ACKR3 by Karsai, Noemi

Subjects: “…Membrane dynamics; Plasma membrane; G protein-receptor kinases…”
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Quantitative proteomic analysis of G-protein signallingin Stagonospora nodorum using isobaric tags forrelative and absolute quantification by Casey, T., Solomon, P., Bringans, S., Tan, Kar-Chun, Oliver, Richard, Lipscombe, R.

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Determination of the ligand pharmacophore required for secondary conformation activation of the human β1-adrenoceptor by Pinto de Sousa, Emanuel

Subjects: “…G protein-coupled receptors(GPCR); β1-AR ; Alprenolol ; Oxprenolol…”
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Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias by Dijon, Nicola C

Subjects: “…G protein coupled receptors…”
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The use of fluorescence correlation spectroscopy to characterize the molecular mobility of fluorescently labelled G protein-coupled receptors by Kilpatrick, Laura E., Hill, Stephen J.

Subjects: “…diffusion; dimerization; fluorescent ligand; fluorescence correlation spectroscopy; G protein-coupled receptor…”
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Identification of a Cyanine-dye labeled peptidic ligand for Y₁R and Y₄R, based upon the Neuropeptide Y C-terminal analogue, BVD-15 by Liu, Mengjie, Richardson, Rachel R., Mountford, Simon J., Zhang, Lei, Tempone, Matheus H., Herzog, Herbert, Holliday, Nicholas D., Thompson, Philip E.

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Investigating a role for heterotrimeric G-proteins in activating TGFβ in asthma by Middlewick, Robert James

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Investigating the mode of action of intracellular loop 1 pepducins at the CXCR4 receptor by Caspar, Birgit

Subjects: “…Peptides; G proteins; Chemokines…”
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Synthesis and evaluation of the first fluorescent antagonists of the human P2Y2 receptor based on AR-C118925 by Conroy, Sean, Kindon, Nicholas, Glenn, Jacqueline, Stoddart, Leigh A., Lewis, Richard James, Hill, Stephen J., Kellam, Barrie, Stocks, Michael J.

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The role of mesenchymal G proteins in pulmonary fibrosis and lung development by Goodwin, Amanda T.

Subjects: “…Pulmonary fibrosis; Pathogenesis; Mesenchymal cells; G protein inhibition; Lung homeostasis; TGFβ isoforms…”
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Investigations into β2-adrenoceptor pharmacology: kinetic analysis, mechanotransduction and allosteric modulation by Cullum, Sean A.

Subjects: “…β2-adrenoceptor; β2AR pharmacology; G protein- coupled receptor action; Pepducins…”
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Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting on the membrane... by Kilpatrick, Laura E., Briddon, Stephen J., Holliday, Nicholas D.

Subjects: “…G protein coupled receptor; Neuropeptide Y; Arrestin; Fluorescence correlation spectroscopy; Bimolecular fluorescence complementation; Endocytosis;…”
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The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response by Roberts, Maxine J., Broome, Rebecca E., Kent, Toby C., Charlton, Steven J., Rosethorne, Elizabeth M.

Subjects: “…cAMP; Idiopathic pulmonary fibrosis; human lung fibroblasts; G protein-coupled receptors; drug discovery…”
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Agonist stimulus trafficking by human prostanoid CRTH2 (DP2) receptors. by McArthur Wilson, Richard John

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Bitter taste receptors in the domestic dog (Canis familiaris) by Gibbs, Matthew

Subjects: “…Bitterness (Taste); Dogs; G proteins; Chemoreceptors…”
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Alternative RNA splicing: contribution to pain and potential therapeutic strategy by Donaldson, Lucy F., Beazley-Long, Nicholas

Subjects: “…Alternative pre-mRNA splicing; ion channel; G-protein coupled receptor; growth factor; nociception; pain…”
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A role for rebinding in the prevalence of on-target side effects of clinically used antipsychotics by Sykes, David A

Subjects: “…G protein coupled receptor…”
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An evaluation of DREADD receptor pharmacology in recombinant cells and astrocytes by Carpenter, Jessica

Subjects: “…Muscarinic receptors; G proteins; Allosteric regulation; Astrocytes;…”
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