Search Results - "FGF21"

Photoperiodic regulation of FGF21 production in the Siberian hamster by Samms, Ricardo J., Fowler, Maxine J., Cooper, Scott, Emmerson, Paul, Coskun, Tamer, Adams, Andrew C., Kharitonenkov, Alexei, Tsintzas, Kostas, Ebling, Francis J.P.

“…FGF21 is an endocrine member of the fibroblast growth factor superfamily that has been shown to play an important role in the physiological response to nutrient deprivation. …”
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FGF21 is an insulin-dependent postprandial hormone in adult humans by Samms, Ricardo J., Lewis, Jo E., Norton, Luke, Stephens, Francis B., Gaffney, Christopher J., Butterfield, Tony, Smith, Dennis, Cheng, Christine, Perfield, James W., Adams, Andrew C., Ebling, Francis J.P., Tsintzas, Kostas

“…Context: Fibroblast growth factor 21 (FGF21) secretion has been shown to respond directly to carbohydrate consumption, with glucose, fructose and sucrose all reported to increase plasma levels of FGF21 in rodents and humans. …”
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Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster by Lewis, Jo E., Samms, Ricardo J., Cooper, Scott, Luckett, Jeni C., Perkins, Alan C., Adams, Andrew C., Tsintzas, Kostas, Ebling, Francis J.P.

“…This was achieved by investigating effects of FGF21 in aged hamsters, which is associated with reduced adiposity. …”
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Dual effects of fibroblast growth factor 21 on hepatic energy metabolism by Samms, Ricardo J., Murphy, Michelle, Fowler, Maxine J., Cooper, Scott, Emmerson, Paul, Coskun, Tamer, Adams, Andrew C., Kharitonenkov, Alexei, Ebling, Francis J.P., Tsintzas, Kostas

Subjects: “…FGF21…”
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The effect of eccentric exercise on skeletal muscle release of novel molecules (myokines) in healthy young individuals by Parmar, Biraj

Subjects: “…Fibroblast Growth Factor 21 (FGF-21)…”
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Cloning, expression and purification of human fibroblast growth factor 21 in Escherichia coli and Pichia pastoris / Farnaz Emamdoust by Farnaz , Emamdoust

“…Fibroblast Growth Factor 21 (FGF21) is a novel target with potential anti diabetic properties that are useful for treatment of hyperglycemia, insulin resistance, hyperlipidemia and metabolic disease. …”
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Postprandial changes in glucose oxidation and insulin sensitivity in metabolic syndrome: Influence of fibroblast growth factor 21 and vitamin D status by Pathak, K., Soares, M., Zhao, Yun, James, A., Sherriff, Jill, Newsholme, Philip

“…Fibroblast growth factor 21 (FGF21) and vitamin D status may improve insulin sensitivity. …”
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Fasting and glucose induced thermogenesis in response to three ambient temperatures: a randomized crossover trial in the metabolic syndrome by Pathak, Kaveri, Woodman, R., James, A., Soares, Mario

“…Venous blood was sampled for clinical chemistry, irisin, and fibroblast growth factor 21(FGF21). A mixed model ANCOVA adjusted data for age, gender, fat mass, fat-free mass and seasonality. …”
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Effective fecal microbiota transplantation for recurrent Clostridioides difficile infection in humans is associated with increased signalling in bile acid-farnesoid X receptor-fibr... by Monaghan, Tanya M., Mullish, Benjamin H., Patterson, Jordan, Wong, Gane K.S., Marchesi, Julian R., Xu, Huiping, Tahseen, Jilani, Kao, Dina

“…Herein, we identify that in addition to restoration of gut microbiota and bile acid profiles, FMT for rCDI is accompanied by a significant, sustained increase in circulating levels of FGF19 and reduction in FGF21. These FGF changes were associated with weight gain post-FMT, to a level not exceeding the pre-rCDI baseline. …”
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Isoquercetin and inulin synergistically modulate the gut microbiome to prevent development of the metabolic syndrome in mice fed a high fat diet by Tan, S., Caparros-Martin, Jose, Matthews, V., Koch, H., O'Gara, Fergal, Croft, K., Ward, Natalie

“…Supplementation with either isoquercetin or inulin had no effect, however mice receiving the combination had attenuated weight gain, improved glucose tolerance and insulin sensitivity, reduced hepatic lipid accumulation, adipocyte hypertrophy, circulating leptin and adipose FGF21 levels, compared to mice receiving the HF diet. …”
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Shining LIGHT on the metabolic role of the cytokine TNFSF14 and the implications on hepatic IL-6 production by Saunders, B., Rudnicka, C., Filipovska, A., Davies, S., Ward, Natalie, Hricova, J., Schlaich, M., Matthews, V.

“…Bone marrow cells from Tnfsf14 deficient mice appeared to promote diet-induced obesity, insulin resistance and reduced FGF21 levels in white adipose tissue and liver. Our novel data suggest that Tnfsf14 ablation exacerbates parameters of the metabolic syndrome under high fat feeding conditions and provides evidence to support the development of TNFSF14 agonists as potential therapeutics in diet-induced obesity. …”
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