Search Results - "Cellular differentiation"
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Investigating the roles of Gfi1/1b transcription factors, Lsd1 histone demethylase and long non coding RNA 1/2 genes in haematopoiesis during zebrafish embryogenesis
Published 2024Subjects: “…Cellular differentiation; zebrafish embryogenesis; Transcriptional repressors; Haematopoiesis…”
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The role of HOXA5 in triple-negative breast cancer (TNBC)
Published 2021“…Dysregulations in HOX gene family expression including HOXA5 transcription factor has been associated with cancer in many ways due to their role in cellular differentiation. However, the role of HOXA5 in stemness and cellular differentiation in TNBC is not clear. …”
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Dynamics of 5-carboxylcytosine during hepatic differentiation: potential general role for active demethylation by DNA repair in lineage specification
Published 2017“…Our data indicate that transient 5caC accumulation is a common feature of two different types (neural/glial and endoderm/hepatic) of cellular differentiation. This suggests that oxidation of 5mC may represent a general mechanism of rearrangement of 5mC profiles during lineage specification of somatic cells in mammals.…”
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Production of recombinant protein by gene cloning from mammalian cell culture
Published 2010“…Cancer is defined as a group of neoplastic diseases broadly characterized by abnormalities of cellular differentiation, maturation and control of growth. …”
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Production of recombinant p53 protein by PCR-based site directed mutagenesis of plasmid DNA
Published 2010“…Cancer is defined as a group of neoplastic diseases broadly characterized by abnormalities of cellular differentiation, maturation and control of growth. …”
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Characterization of periodontal fibroblast spheroids in vitro, interaction with 3d membranes and potential for tissue regeneration
Published 2012“…Spheroid culture is a form of three dimensional cell culture that promotes cellmatrix interaction and cellular differentiation without recourse to exogenous growth factors. …”
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Transforming growth factor-beta signalling in the regulation of epstein-barr virus infection in nasopharyngeal epithelial cells / Sharmila Velapasamy
Published 2018“…Collectively, the results of this study demonstrate that disruption of TGF-β signalling supports stable EBV infection in NPE cells, possibly by suppressing cellular differentiation, EBV-induced senescence and EBV lytic cycle induction. …”
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Developmental functions of the dynamic DNA methylome and hydroxymethylome in the mouse and zebrafish: similarities and differences
Published 2018“…Our analysis may provide an insight into the general principles of epigenetic regulation of animal development and cellular differentiation.…”
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Regeneration of Syzygium myrtifolium walp. from seed fragments – evidence of polyembryony?
Published 2023“…Future work should look into the intrinsic signals and external cues that regulate the cellular differentiation and development in the seed fractions in revealing the polyembryony in S. myrtifolium.…”
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Id4 functional analysis during neurogenesis using zebrafish as a model organism
Published 2017“…Therefore Id-bHLH heterodimerisation results in inhibition of bHLH activity which drives cellular differentiation. Id4 plays an important role in proliferating cells maintaining neural stem cell pool and controlling the timing of differentiation as well as apoptosis in the mouse. …”
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Effects of thymoquinone supplementation on cyclophosphamide toxicity of mouse embryo in vitro
Published 2014“…This study evaluates the prophylactic effect of thymoquinone supplementation on culture medium to ameliorate cyclophosphamide-induced alterations in cellular differentiation and proliferation during embryo development in vitro. …”
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Microvessel density in different grades of oral squamous cell carcinoma and its relationship with keratin pearl
Published 2016“…The findings suggested that vascularity in OSCC is associated with its cellular differentiation and also associated with keratin pearl formation.…”
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The effect of gamma irradiation on selected growth factors and receptors mRNA in glycerol cryopreserved human amniotic membrane
Published 2015“…These growth factors are key factors in regulating many cellular processes such as cellular growth, proliferation and cellular differentiation. The current study aimed to explore the effect of glycerol cryopreservation and gamma irradiation on the selected growth factors and receptors mRNA present in HAM. …”
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Lactation failure in crossbred Sahiwal Friesian cattle
Published 2001“…The cellular consequences of residual milk accumulation were evident in the activities of acetyl-CoA carboxylase, fatty acid synthetase and galactosyltransferase, key enzyme markers of cellular differentiation, which decreased in glands undergoing lactation failure and were lower than values measured in tissue of control cows. …”
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Exploring three dimensional culture system for cartilage tissue engineering application: a review
Published 2014“…Three-dimensional in vitro cartilage models allow the study of cell-cell and cell-extracellular matrix interactions with addition to the influence of the micro environment on cellular differentiation and proliferation. It simulates normal cell morphology, proliferation, differentiation and migrations, better than the 2D cell culture. …”
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Chondrocytes-induced SOX5/6/9 and TERT genes for articular cartilage tissue engineering: hype or hope?
Published 2017“…Numerous attempts have been made in the TERM field to study factors that support specific cellular differentiation and quality tissue formation which include the use of gene transfer method. …”
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MiR-3099 is overexpressed in differentiating 46c mouse embryonic stem cells upon neural induction
Published 2014“…This study aims to determine the expression of miR-3099 during cellular differentiation of 46C mouse embryonic stem cells after neural induction with N2/B27 medium. …”
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The effect of platelet rich concentrate on the regenerative capacity of mesenchymal stromal cells and its potential application in cartilage repair / Shani Samuel
Published 2017“…The study was further extended to compare the expression of lineage-specific markers both at the mRNA and protein levels of cells undergoing osteogenesis, adipogenesis and chondrogenesis under the influence of PRC to those cultured in the standard lineage-specific differentiation media during 24 days of culture (i.e. typical duration to achieve complete cellular differentiation to the common mesenchymal lineages). …”
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