Search Results - "Cas9"

CRISPR-Cas9-mediated genome editing of the extracellular matrix gene TNC in human fibroblasts by Brunetti, Giulio

Subjects: “…CRISPR-Cas9…”
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CRISPR-Cas9 gene targeting of human induced pluripotent stem cells to generate a palette of optical reporter cell lines towards investigating hypertrophic cardiomyopathy by Bhagwan, Jamie R.

Subjects: “…Hypertrophic cardiomyopathy; CRISPR-Cas9; In vitro study; Mutations…”
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Genetic screens in intestinal organoid (mini-gut) culture using CRISPR-Cas-9 System and studying the role of FBXL5 in colorectal cancer cells by Jinks, Nicholas

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Understanding the pathogenesis and potential therapeutics of Myotonic dystrophy by Verma, Ayushri

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Simplified footprint-free Cas9/CRISPR editing of cardiac-associated genes in human pluripotent stem cells by Kondrashov, Alexander, Hoang, Minh Duc, Smith, James G.W., Bhagwan, Jamie R., Duncan, Gary, Mosqueira, Diogo, Barbadillo Munoz, Maria, Vo, Nguyen T.N., Denning, Chris

Subjects: “…Cas9/CRISPR; PiggyBac; gene editing; human pluripotent stem cells; genetic disease modelling; cardiomyocytes…”
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RNA-guided integration of diverse DNA molecules by casposase-Cas9 fusions by Lau, Chun H.

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Developments in genetic engineering of novel acetogens by Mansfield, Robert Patrick William

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Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs by Bertero, Alessandro, Pawlowski, Matthias, Ortmann, Daniel, Snijders, Kirsten, Yiangou, Loukia, Cardoso de Brito, Miguel, Brown, Stephanie, Bernard, William G., Cooper, James D., Giacomelli, Elisa, Gambardella, Laure, Hannan, Nicholas R.F., Iyer, Dharini, Sampaziotis, Fotios, Serrano, Felipe, Zonneveld, Mariëlle C.F., Sinha, Sanjay, Kotter, Mark, Vallier, Ludovic

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Expansion of the genome editing toolbox of Clostridium autoethanogenum by Seys, François M.

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Disease modeling hypertrophic cardiomyopathy using CRISPR/Cas9 genome editing technology in human pluripotent stem cell-derived cardiomyocytes by Mosqueira, Diogo

Subjects: “…Hypertrophic cardiomyopathy; disease modelling; CRISPR/Cas9; genome-edited human pluripotent stem cell-cardiomyocytes; R453C-βMHC…”
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CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic... by Mosqueira, Diogo, Mannhardt, Ingra, Bhagwan, Jamie R., Lis-Slimak, Katarzyna, Katili, Puspita, Scott, Elizabeth, Hassan, Mustafa, Prondzynski, Maksymilian, Harmer, Stephen C., Tinker, Andrew, Smith, James G.W., Carrier, Lucie, Williams, Philip M., Gaffney, Daniel, Eschenhagen, Thomas, Hansen, Arne, Denning, Chris

Subjects: “…Hypertrophic cardiomyopathy; Disease modelling; CRISPR/Cas9; Genome-edited human pluripotent stem cell-cardiomyocytes; R453C-βMHC…”
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Studying novel sporulation genes in Clostridium sporogenes by Rizvi, Syeda-Rubab-Zehra

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Gene editing the phytoene desaturase alleles of Cavendish banana using CRISPR/Cas9 by Eftekhari, Fatima, Dugdale, B., Kleidon, J., Brinin, A., Shand, K., Waterhouse, P., Dale, J.

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Can human pluripotent stem cell-derived cardiomyocytes advance understanding of muscular dystrophies? by Kalra, Spandan, Montanaro, Federica, Denning, Chris

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Metabolic engineering of parageobacillus thermoglucosidasius for sustainable production of fuels and chemicals by Madika, Abubakar

Subjects: “…Thermophile; Parageobacillus thermoglucosidasius NCIMB 11955; ethanol; isobutanol; 3-hydroxypropionate (3-HP); pMTL60000; modular vector; theophylline-responsive CRISPR/Cas9; metabolic engineering; barley straw hydrolysate; malonyl-CoA pathway; consolidated bioprocessing (CBP)…”
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Cardiomyocytes from human pluripotent stem cells: from laboratory curiosity to industrial biomedical platform by Denning, Chris, Borgdorff, Viola, Crutchley, James, Firth, Karl S.A., George, Vinoj, Kalra, Spandan, Kondrashov, Alexander, Hoang, Minh Duc, Mosqueira, Diogo, Patel, Asha, Prodanov, Ljupcho, Rajamohan, Divya, Skarnes, William C., Smith, James G.W., Young, Lorraine E.

Subjects: “…Human embryonic stem cells; human induced pluripotent stem cells; cas9/CRISPR genome editing; cardiomyocytes; drug screening; disease modelling; maturation factors; muscular thin films; engineered heart tissue; automated scalability; high content platforms; calcium imaging; electrophysiology; mitochondria; contractility…”
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