Search Results - "Cancer Research UK"

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  1. 1
    The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome

    The expression of RUNX3 in colorectal cancer is associated with disease stage and patient outcome by Soong, R., Shah, N., Peh, B., Chong, P., Ng, S., Zeps, Nikolajs, Joseph, D., Salto-Tellez, M., Iacopetta, B., Ito, Y.

    Published 2009
    “…These results support a role for RUNX3 as a tumour suppressor in colorectal cancer. © 2009 Cancer Research UK.…”
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  2. 2
    Malignant mesotheliomas in former miners and millers of crocidolite at Wittenoom (Western Australia) after more than 50 years follow-up

    Malignant mesotheliomas in former miners and millers of crocidolite at Wittenoom (Western Australia) after more than 50 years follow-up by Berry, G., Reid, Alison, Aboagye-Sarfo, P., De Klerk, N., Olsen, N., Merler, E., Franklin, P., Musk, A.

    Published 2012
    “…It is predicted that about another 60 to 70 deaths with mesothelioma may occur in men by 2020. © 2012 Cancer Research UK All rights reserved.…”
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  3. 3
    Treatment decisions and survival for people with small-cell lung cancer

    Treatment decisions and survival for people with small-cell lung cancer by Powell, H.A., Tata, L.J., Baldwin, D.R., Potter, V.A., Stanley, R.A., Khakwani, A., Hubbard, R.B.

    Published 2014
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  4. 4
    Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer

    Low stromal Foxp3+ regulatory T-cell density is associated with complete response to neoadjuvant chemoradiotherapy in rectal cancer by McCoy, M., Hemmings, C., Miller, T., Austin, S., Bulsara, M., Zeps, Nikolajs, Nowak, A., Lake, R., Platell, C.

    Published 2015
    “…© 2015 Cancer Research UK Background:Foxp3+ regulatory T cells (Tregs) play a vital role in preventing autoimmunity, but also suppress antitumour immune responses. …”
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  5. 5
    Exposure to bisphosphonates and risk of common non-gastrointestinal cancers: series of nested case–control studies using two primary-care databases

    Exposure to bisphosphonates and risk of common non-gastrointestinal cancers: series of nested case–control studies using two primary-care databases by Vinogradova, Yana, Coupland, Carol, Hippisley-Cox, Julia

    Published 2013
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  6. 6
    WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma

    WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma by Rogers, H.A., Sousa, S., Salto, C., Arenas, E., Coyle, B., Grundy, Richard G.

    Published 2012
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  7. 7
    The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs)

    The role of the WNT/β-catenin pathway in central nervous system primitive neuroectodermal tumours (CNS PNETs) by Rogers, H.A., Ward, J.H., Miller, S., Lowe, J., Coyle, B., Grundy, Richard G.

    Published 2013
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  8. 8
    RT Prepare: a radiation therapist-delivered intervention reduces psychological distress in women with breast cancer referred for radiotherapy

    RT Prepare: a radiation therapist-delivered intervention reduces psychological distress in women with breast cancer referred for radiotherapy by Halkett, Georgia, O Connor, M., Jefford, M., Aranda, S., Merchant, S., Spry, N., Kane, Robert, Shaw, T., Youens, David, Moorin, Rachael, Schofield, P.

    Published 2018
    “…© 2018 Cancer Research UK Background: The aims of this study were to determine whether a radiation therapist-led patient education intervention (RT Prepare) reduced breasts cancer patients’ psychological distress (primary endpoint); anxiety, depression and concerns about radiotherapy, and increased knowledge of radiotherapy and preparedness (secondary endpoints). …”
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  9. 9
    A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate

    A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate by Falasca, Marco, Chiozzotto, D., Godage, H., Mazzoletti, M., Riley, A., Previdi, S., Potter, B., Broggini, M., Maffucci, T.

    Published 2010
    “…It is interesting to note that 2-O-Bn-InsP5 also inhibits the mammalian target of rapamycin (mTOR) in vitro.Conclusions: InsP5 and 2-O-Bn-InsP5 may represent lead compounds to develop novel inhibitors of the PI3K/Akt pathway (including potential dual PDK1/mTOR inhibitors) and novel potential anti-cancer drugs. © 2010 Cancer Research UK All rights reserved.…”
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  10. 10
    Health-related quality of life after treatment for bladder cancer in England

    Health-related quality of life after treatment for bladder cancer in England by Mason, Samantha J., Downing, Amy, Wright, Penny, Hounsome, Luke, Bottomley, Sarah E., Corner, Jessica, Richards, Mike, Catto, James W., Glaser, Adam W.

    Published 2018
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  11. 11
    Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms?: a longitudinal data-linkage study in England

    Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms?: a longitudinal data-linkage study in Engla... by Renzi, C., Lyratzopoulos, G., Card, Timothy R., Chu, T., Macleod, U., Ratchet, B.

    Published 2016
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  12. 12
    Smoking cessation and survival in lung, upper aero-digestive tract and bladder cancer: cohort study

    Smoking cessation and survival in lung, upper aero-digestive tract and bladder cancer: cohort study by Koshiaris, C., Aveyard, P., Oke, J., Ryan, R., Szatkowski, Lisa, Stevens, R., Farley, A.

    Published 2017
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  13. 13
    MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer

    MYC regulation of Glutamine-Proline regulatory axis is key in Luminal B breast cancer by Craze, Madeleine L., Cheung, Hayley, Jewa, Natasha, Coimbra, Nuno D.M., Soria, Daniele, El-Ansari, Rokaya, Aleskandarany, Mohammed A., Cheng, Kiu Wai, Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Rakha, Emad, Green, Andrew R.

    Published 2017
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  14. 14
    Mediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes

    Mediator complex (MED) 7: a biomarker associated with good prognosis in invasive breast cancer, especially ER+ luminal subtypes by Joseph, Chitra, Macnamara, Olivia, Craze, Madeleine, Russell, Roslin, Provenzano, Elena, Nolan, Christopher C., Diez-Rodriguez, Maria, Sonbul, Sultan N., Aleskandarany, Mohammed A., Green, Andrew R., Rakha, Emad A., Ellis, Ian O., Mukherjee, Abhik

    Published 2018
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  15. 15
    Risk of venous thromboembolism in people with lung cancer: a cohort study using linked UK healthcare data

    Risk of venous thromboembolism in people with lung cancer: a cohort study using linked UK healthcare data by Walker, Alex J., Baldwin, David R., Card, Timothy R., Powell, Helen A., Hubbard, Richard B., Grainge, Matthew J.

    Published 2016
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  16. 16
    Ovarian cancer and smoking: individual participant meta-analysis including 28 114 women with ovarian cancer from 51 epidemiological studies

    Ovarian cancer and smoking: individual participant meta-analysis including 28 114 women with ovarian cancer from 51 epidemiological studies by Binns, Colin, Lee, Andy

    Published 2012
    “…The substantial variation in smoking-related risks by tumour subtype is important for understanding ovarian carcinogenesis. Funding: Cancer Research UK and MRC.…”
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  17. 17
    The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes

    The multifunctional solute carrier 3A2 (SLC3A2) confers a poor prognosis in the highly proliferative breast cancer subtypes by El Ansari, Rokaya, Craze, Madeleine L., Diez-Rodriguez, Maria, Nolan, Christopher C., Ellis, Ian O., Rakha, Emad A., Green, Andrew R.

    Published 2018
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  18. 18
    KI67 and DLX2 predict increased risk of metastasis formation in prostate cancer: a targeted molecular approach

    KI67 and DLX2 predict increased risk of metastasis formation in prostate cancer: a targeted molecular approach by Green, William J.F., Ball, Graham, Hulman, Geoffrey, Johnson, Catherine, Van Schalwyk, Gerry, Ratan, Hari L., Soria, Daniel, Garibaldi, Jonathan M., Parkinson, Richard, Hulman, Joshua, Rees, Robert, Powe, Desmond G.

    Published 2016
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  19. 19
    Rho-GTPase activating protein 18: a biomarker associated with good prognosis in invasive breast cancer

    Rho-GTPase activating protein 18: a biomarker associated with good prognosis in invasive breast cancer by Aleskandarany, Mohammed A., Sonbul, Sultan N., Surridge, Rachel, Mukherjee, Abhik, Caldas, Carlos, Diez-Rodriguez, Maria, Ashankyty, I., Albrahim, Khalil I., Elmouna, Ahmed M., Aneja, Ritu, Martin, Stewart G., Ellis, Ian O., Green, Andrew R., Rakha, Emad A.

    Published 2017
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  20. 20
    Postoperative exercise rehabilitation after elective colorectal cancer surgery

    Postoperative exercise rehabilitation after elective colorectal cancer surgery by Paul, Melanie Alya

    Published 2025
    “…Introduction Colorectal cancer (CRC) is common, accounting for approximately 11% of all new cancer cases, and is primarily a cancer associated with increasing age (Cancer Research UK, 2021). Surgery is usually the most appropriate option (if feasible and depending on staging) to try to achieve cancer free status. …”
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