Search Results - "CRISPR"

The role of Cas8 in type I CRISPR interference by Cass, Simon, Haas, Karina, Stoll, Britta, Alkhnbashi, Omer, Sharma, Kundan, Urlaub, Henning, Backofen, Rolf, Marchfelder, Anita, Bolt, Edward

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Campylobacter jejuni acquire new host-derived CRISPR spacers when in association with bacteriophages harboring a CRISPR-like Cas4 protein by Hooton, Steven P.T., Connerton, Ian F.

“…Type II CRISPR systems are found in association with combinations of genes encoding the CRISPR-associated Cas1, Cas2, Cas4 or Csn2, and Cas9 proteins. …”
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Part A: Application of fluorescent markers onto CRISPR-associated proteins/ Part B: Substitution of cysteine residues in CRISPR associated Protein Cas1 by Parr, Lochlan

Subjects: “…CRISPR associated proteins; mstayGold…”
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CRISPR-Cas immunity: analysis of adaptation and interference reactions in prokaryotes by Cass, S.D.B.

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Development of a high-throughput screen for the study of CRISPR spacer acquisition by Braithwaite, Jack

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Investigating a human DNA repair helicase that supports CRISPR editing by Cubbon, Andrew

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Characterising Host Factors Required for CRISPR Cas Adaptation in Escherichia coli by Edwards, Harry

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The CRISPR growth spurt: from bench to clinic on versatile small RNAs by Bayat, Hadi, Omidi, Meisam, Masoumeh, Rajabibazl, Rahimpour, Azam, Sabri, Suriana

“…Clustered Regulatory Interspaced Short Palindromic Repeats (CRISPR) in association with CRISPR associated protein (Cas) is an adaptive immune system, playing a pivotal role in the defense of bacteria and archaea. …”
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Harnessing CRISPR-Cas to combat COVID-19: from diagnostics to therapeutics by Kok, Gan Chan, Geik, Yong Ang, Yu, Choo Yee, Chan, Yean Yean

“…In this review, we highlight the recent advances in CRISPR–Cas-based nucleic acid detection strategies and the application of CRISPR–Cas as a potential antiviral agent in the context of COVID-19.…”
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CRISPR-Cas knockout of miR21 reduces glioma growth by Nieland, Lisa, Solinge, Thomas S. van, Cheah, Pike See, Morsett, Liza M., Khoury, Joseph El, Rissman, Joseph I., Kleinstiver, Benjamin P., Broekman, Marike L. D., Breakefield, Xandra O., Abels, Erik R.

“…Overall, we identified miR-21 as a potential target for CRISPR-based therapeutics in glioma.…”
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The enhancement of plant disease resistance using CRISPR/Cas9 technology by Mohd Azman, Amier Asyraf, Mohammad Fouad Iskandar,, Haziq Iskandar, Muhammad Zaidi Leong, Muhamad Nur Hafiz Leong, Mohd Fauzi, Noor Akhmazillah

“…For the past recent years, multiple methods for site directed modification such as clustered regularly interspaced short palindrome repeats (CRISPR)/CRISPR�associated protein 9(cas9), zinc finger nucleases (ZFNs) and transcription activator�like effector nucleases (TALENs). …”
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Characterization of CRISPR mutants targeting genes modulating pectin degradation in ripening tomato by Wang, Duoduo, Samsulrizal, Nurul Hidayah, Yan, Cheng, Allcock, Natalie, Craigon, Jim, Blanco-Ulate, Barbara, Ortega-Salazar, Isabel, E. Marcus, Susan, Bagheri, Hassan Moeiniyan, Perez, Laura, Fraser, Paul D, Foster, Timothy, Fray, Rupert, Knox, J. Paul, Seymour, Graham B

“…Here we report the generation of CRISPR-based mutants in the ripening-related genes encoding the pectin-degrading enzymes pectate lyase (PL), polygalacturonase 2a (PG2a), and β-galactanase (TBG4). …”
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Characterisation of CRISPR mutants targeting genes modulating pectin degradation in ripening tomato by Wang, Duoduo, Samsulrizal, Nurul Hidayah, Cheng, Yan, Allcock, Natalie, Craigon, Jim, Blanco-Ulate, Barbara, Ortega-Salazar, Isabel, E. Marcus, Susan, Moeiniyan Bagheri, Hassan, Perez-Fons, Laura, D. Fraser, Paul, Foster, Timothy, Fray, Rupert, Knox, J. Paul, B. Seymour, Graham

“…Here we report the generation of CRISPR-based mutants in the ripening-related genes encoding the pectin degrading enzymes pectate lyase (PL), polygalacturonase 2a (PG2a) and β-galactanase (TBG4). …”
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Molecular insights into DNA interference by CRISPR-associated nuclease-helicase Cas3 by Gong, Bei, Shin, Minsang, Sun, Jiali, Jung, Che-Hun, Bolt, Edward L., van der oost, John, Kim, Jeong-Sun

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CRISPR systems - molecular mechanisms of the interaction between Cas1 and DnaK by Stewart, Alison L.

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Applications of a high-throughput screen detecting CRISPR-Cas spacer acquisition by Cannon, Christopher

“…The arms race between prokaryotes and their foreign genetic elements has driven the evolution of a diverse and enigmatic array of immune systems. CRISPR-Cas systems uniquely provide adaptive immunity against these foreign elements. …”
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Harnessing the potential of mutation breeding, CRISPR genome editing, and beyond for sustainable agriculture by Nor A’azizam, Nelissa Maisara, Chopra, Sakshi, Guleria, Praveen, Kumar, Vineet, Abd Rahim, Muhamad Hafiz, Yaacob, Jamilah Syafawati

“…Together, mutation breeding and CRISPR can potentially address future food demands. …”
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Combinatorial Crispr/Cas9 For Suppression Of Latent Hiv-1 Provirus In Vitro by Ravichantar, Nithya

“…By targeting the promoter of HIV-1 (LTR), CRISPR/Cas9 can disrupt the latent reservoirs. Here, we designed an improved CRISPR/Cas9 system, combinatorial CRISPR/Cas9 to concurrently knockdown multiple HIV-1 genes: structural (Pol and Gag), regulatory (Rev and Tat) and accessory genes (Vif). …”
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Electrosprayed alginate nanoparticles as CRISPR Plasmid DNA delivery carrier: preparation, optimization, and characterization by Alallam, Batoul, Altahhan, Sara, Taher, Muhammad, Mohd Nasir, Mohd Hamzah, Abd Almonem, Doolaanea

“…Therapeutic gene editing is becoming more feasible with the emergence of the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein (Cas) system. However, the successful implementation of CRISPR/Cas9-based therapeutics requires a safe and efficient in vivo delivery of the CRISPR components, which remains challenging. …”
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Development of CRISPR-cas9 ribonucleoprotein complex platform for disruption of candidalysin in Candida albicans by Ahmad, Hasna, Ramzi, Ahmad Bazli, Arzmi, Mohd Hafiz

“…The method is a faster, simpler and more efficient alternative to plasmid- based CRISPR-Cas9 gene editing in C. albicans.…”
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