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Anti-inflammatory efficacy and skin irritation study of Cleome gynandra extract: an animal model and pre-clinical evaluation by Muhammad Aiman, H.I., Koh, S.P., Sew, Y.S., Sanimah, S., Chandradevan, M., Muhammad Nazrul, H., Armania, N.

“…Data collected evidently showed a significantly higher (p<0.05) percentage of recovery rate (70.21±5.14%) in rats treated with C. gynandra cream when compared to the negative control (27.43±4.75%) and basal cream (55.8±4.61%), indicating that C. gynandra cream effectively reduced inflammation symptoms in rat ear edema model study. The expressions of all pro-inflammatory cytokines and acute inflammatory-related genes were significantly down-regulated in C. gynandra cream-treated group than untreated group (negative control). …”
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