Search Results - "ANTITUMOR-ACTIVITY"

Novel hybrids of natural β-elemene bearing isopropanolamine moieties: synthesis, enhanced anticancer profile, and improved aqueous solubility by Chen, Jichao, Wang, Tianyu, Xu, Shengtao, Aijun, Lin, Yao, Hequan, Xie, Weijia, Zhu, Zheying, Xu, Jinyi

Subjects: “…β-Elemene; Isopropanolamine; Dimer; Antitumor activity; Aqueous solubility…”
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Design, synthesis and biological evaluation of novel nitric oxidedonating protoberberine derivatives as antitumor agents by Chen, Jichao, Wang, Tianyu, Xu, Shengtao, Lin, Aijun, Yao, Hequan, Xie, Weijia, Zhu, Zheying, Xu, Jinyi

Subjects: “…Berberine; Palmatine; Nitric oxide (NO) donor; Hybrid compound; Antitumor activity…”
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Discovery of novel antitumor nitric oxide-donating b-elemene hybrids through inhibiting the PI3K/Akt pathway by Chen, Jichao, Wang, Tianyu, Xu, Shengtao, Zhang, Pengfei, Lin, Aijun, Wu, Liang, Yao, Hequan, Xie, Weijia, Zhu, Zheying, Xu, Jinyi

Subjects: “…β-Elemene; Furoxan; Antitumor activity; Apoptosis; PI3K/Akt pathway…”
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PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer by Serra, V., Scaltriti, M., Prudkin, L., Eichhorn, Pieter, Ibrahim, Y.H., Chandarlapaty, S., Markman, B., Rodriguez, O., Guzman, M., Rodriguez, S., Gili, M., Russillo, M., Parra, J.L., Singh, S., Arribas, J., Rosen, N., Baselga, J.

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