Search Results - "2channel"

2-Channel AVM System: software tool for calibration by Sediono, Wahju

Get full text
Get full text
Get full text

Three Ca2+ channel inhibitors in combination limit chronic secondary degeneration following neurotrauma by Savigni, D., O'Hare Doig, R., Szymanski, C., Bartlett, C., Lozic, I., Smith, N., Fitzgerald, Melinda

“…Treatment using inhibitors of specific Ca 2+ channels has shown promise in preclinical studies, but clinical trials have been disappointing and combinatorial approaches are needed. …”
Get full text

TRPM2 channel in microglia as a new player in neuroinflammation associated with a spectrum of central nervous system pathologies by Malko, Philippa, Syed Mortadza, Sharifah Alawieyah, McWilliam, Joseph, Jiang, Lin Hua

“…These findings lead to a growing interest in the TRPM2 channel, a new player in neuroinflammation, as a novel therapeutic target for CNS diseases.…”
Get full text
Get full text

The TRPM2 channel nexus from oxidative damage to Alzheimers pathologies: an emerging novel intervention target for age-related dementia by Jiang, Lin-Hua, Li, Xin, Syed Mortadza, Sharifah Alawieyah, Lovatt, Megan, Yang, Wei

“…The 'hypothesis' based on these new findings discusses the prospect of considering the TRPM2 channel as a novel therapeutic target for intervening AD and age-related dementia.…”
Get full text
Get full text

Predisposition to Alzheimer’s and age-related brain pathologies by PM2.5 exposure: Perspective on the roles of oxidative stress and TRPM2 channel by Syed Mortadza, Sharifah A., Lu, Wang, Lin, Yu Wei

“…Documented evidence suggests critical engagement of oxidative stress and TRPM2 channel activation in various PM2.5-induced cellular effects. …”
Get full text

Signalling mechanism in TRPM2-dependent copper- induced HT22 cell death by Rathakrishnan, Sharani, Hazanol, Iffa Nadhira, Dali, Mohd Haziq Izzazuddin, Sha’fie, Muhammad Syahreel Azhad, Ahmad, Syahida, Alitheen, Noorjahan Banu, Syed Mortadza, Sharifah Alawieyah

“…It is known that the activation of TRPM2 channel is via the increase of intracellular reactive oxygen species (ROS). …”
Get full text

Ethanol induces microglial cell death via the NOX/ROS/PARP/TRPM2 signalling pathway by Sha’fie, Muhammad Syahreel Azhad, Rathakrishnan, Sharani, Hazanol, Iffa Nadhira, Mohd Dali, Mohd Haziq Izzazuddin, Khayat, Mohd Ezuan, Ahmad, Syahida, Hussin, Yazmin, Alitheen, Noorjahan Banu, Jiang, Lin Hua, Syed Mortadza, Sharifah Alawieyah

“…H2O2/EtOH-induced cell death was inhibited by treatment with TRPM2 channel inhibitors and also treatment with poly(ADP-ribose) polymerase (PARP) inhibitors, demonstrating the critical role of PARP and the TRPM2 channel in EtOH-induced cell death. …”
Get full text
Get full text

The effect of period of time (T) from 900Hz – 1820Hz of transcutaneous electrical nerve stimulator for biomedical application by A. Miskon, M. S. Salleh, S. N. M. Tawil, Mohd Salman Mohd Sabri, N. R. S. Rokmanuddin

“…The main role of TENS is as a pain relief to users by replacing the usage of analgesic or drug. 2-Channel Defence Transcutaneous Electrical Stem Stimulator (2-Channel DTES) device and 5-Channel Defence Transcutaneous Electrical Stem Stimulator (5-Channel DTES) has been developed to improve the previous TENS devices but there were some shortcomings of the devices such as incoming noise in circuit as well as different measurement results if compared to simulation and experimental test. …”
Get full text
Get full text

Smartplug Home Automation System (SHAS) Using Internet Of Things (IoT) by Wan Muhammad Adam, Azmi

“…In this project, this system consists of 3 main components namely, Arduino ESP8266, 2 Channel AC Relay and Extension Plug. 2 Channel AC Relay will control the high voltage current connected directly from the Extension Plug. …”
Get full text
Get full text

Specific combinations of ion channel inhibitors reduce excessive Ca2+ influx as a consequence of oxidative stress and increase neuronal and glial cell viability in vitro by O'Hare Doig, R., Bartlett, C., Smith, N., Hodgetts, S., Dunlop, S., Hool, L., Fitzgerald, Melinda

“…Combinations of Ca 2+ channel inhibitors have been proposed as an effective means to prevent excess Ca 2+ flux and death of neurons and glia following neurotrauma in vivo. …”
Get full text

Cardiac depressant and vasodialatory effect of flaxseed - basis for the medicinal use in hypertension by Palla, Amber Hanif, Ur Rehman, Najeeb, Siddiqi, Hasan Salman, Gilani, Anwar-Ul-Hassan, Siddiqui, Bina Shaheen, Ilyas, Maimoona, Perwaiz, Sobiya

“…All these findings indicate that Flaxseed may mediate its antihypertensive activity by the alpha-1 receptor antagonist and Ca+2 channel blocking-like activity, which may account for its efficacy in hypertension.…”
Get full text
Get full text

Development of Pc-Based Multi-Channel Measurement Unit by Omer, Abdu Idris

“…This study was mainly concerned with the design of 2-channel isolated current measurement board. The board can be plugged into one of the input/output (I/O) slots in the IBMlPC/ AT or compatibles. …”
Get full text
Get full text

Scientific basis for use of Pyrus pashia Buch.-Ham. ex D. Don. fruit in gastrointestinal, respiratory and cardiovascular ailments by Janbaz, Khalid Hussain, Ahsan, Muhammad Zaeem, Saqib, Fatima, Imran, Imran, Zia-Ul-Haq, Muhammad, Rashid, Muhammad Abid, Jaafar, Hawa Z. E., Moga, Marius

“…The spasmolytic and bronchodilator activities are likely to be mediated through blockade of Ca2+ channels, while vasoconstrictive activity may be due to presence of a α-adrenergic, muscarinic, serotonergic, and angiotensin II agonistic component.…”
Get full text

Two channel data acquisition system for heart sound segmentation algorithm based on instantaneous energy of electrocardiogram by Malarvili, M. B., J., M. Najeb, Ismail, Kamarulafizam

“…This paper presents the hardware design of 2- channel data acquisition system for heart sound and Electrocardiogram (ECG) to capture the heart sound and ECG simultaneously from patients; and software algorithm to detect the first heart sound (S1) and second heart sound(S2). …”
Get full text
Get full text

Dual channel double wavelength method in optical fiber-based gas sensor for carbon dioxide detection by Razali, Muda, Norhana, Arsad, Nur Hazliza, Ariffin, Amran, Abdul Hadi

“…The sensor system comprises of a broadband filament emitter acting as the Infrared (IR) light source, Chalcogenide Infrared (CIR) Optical Fibers, two Pyroelectric detectors which been fitted built- in with a limited bandpass CO2 channel and a reference channel. The sensor additionally uses calcium fluoride (CaF2) limit bandpass (NBP) channel for recognition of CO2 gas without cross-sensitivity to different gasses exist in the surrounding environment. …”
Get full text
Get full text

A 40 Gb/s duty-cycle/polarization division multiplexing system by Dastgiri, Kosar S., Seyedzadeh, Saleh, Kakaee, Majid H.

“…In the proposed system each PDM channel carries 2-channel DCDM where each user is operating at data rate of 10 Gb/s which forms 2 × 2 × 10 Gb/s optical system. …”
Get full text
Get full text

Morphological assessment of river stability: review of the most influential parameters by Haron, Nor Azidawati, Yusuf, Badronnisa, Sulaiman, Mohd Sofiyan, Ab Razak, Mohd Shahrizal, Siti Nurhidayu

“…The most influential parameters (top 5) that determine the stability of a river system are (1) channel forms, (2) channel dimensions, (3) channel substrates, (4) channel pattern, and (5) bank profile. …”
Get full text

Hand and elbow gesture recognition based on electromyography signal by Abdulhafidh Al-Dubai, Ala Abobakr

“…Whereas, the EMG signals are collected using the software Lab-Chart 7 with 2 channel and 5 electrodes. The pre-processing of the EMG raw signals is presented using a 6th order Butterworth band pass filter, low and high pass filter with normalization. …”
Get full text
Get full text
Get full text

Dominant-negative effect of a missense variant in the TASK-2 (KCNK5) K+ channel associated with Balkan endemic nephropathy by Reed, Alan, Bucci, Giovanna, Abd-Wahab, Firdaus, Tucker, Stephen J.

“…In this study we show that this variant (T108P) results in a complete loss of channel function and is associated with a major reduction in TASK-2 channel subunits at the cell surface. Furthermore, these mutant subunits have a suppressive or ‘dominant-negative’ effect on channel function when coex- pressed with wild-type subunits. …”
Get full text
Get full text

Subcellular calcium dynamics in a whole-cell model of an atrial myocyte by Thul, Ruediger, Coombes, Stephen, Roderick, H. Llewelyn, Bootman, Martin D.

“…Furthermore, we demonstrate that altering the strength of Ca(2+) release, ryanodine receptor refractoriness, the magnitude of initiating stimulus, or the introduction of stochastic Ca(2+) channel activity can cause the nucleation of proarrhythmic traveling Ca(2+) waves. …”
Get full text