Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive
Dialysis membrane containing cellulose acetate (CA) as polymer, formic acid (FA) as solvent and D-glucose monohydrate as additive was prepared by phase inversion method. The main objective of this study is to investigate the influence of D-glucose monohydrate as an additive on the performance of dia...
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| Format: | Article |
| Language: | English |
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Penerbit UTM Press
2009
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| Online Access: | http://eprints.utm.my/9992/ http://eprints.utm.my/9992/1/UTMjurnalTEK_51F_DIS%5B06%5D.pdf |
| _version_ | 1848891991209803776 |
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| author | Idris, Ani Hew, Ka Yee Chan, Mieow Kee |
| author_facet | Idris, Ani Hew, Ka Yee Chan, Mieow Kee |
| author_sort | Idris, Ani |
| building | UTeM Institutional Repository |
| collection | Online Access |
| description | Dialysis membrane containing cellulose acetate (CA) as polymer, formic acid (FA) as solvent and D-glucose monohydrate as additive was prepared by phase inversion method. The main objective of this study is to investigate the influence of D-glucose monohydrate as an additive on the performance of dialysis membrane in terms of urea and creatinine clearance. The concentration of D-glucose is varied from 2 to 10 wt%. Microwave heating which is capable of reducing dissolution time was used to dissolve the CA polymer in the formic acid solvent. Results revealed that the membrane produced from the 20 wt% cellulose acetate, 70 wt% formic acid and 10 wt% D-glucose monohydrate gives the best performance with urea and creatinine clearance of 49.77% and 19.54% respectively. When testing the same membranes with BSA solutions, it gives a BSA rejection rate as high as 96.78%, which seems to be comparable with the commercial cellulose acetate dialysis membranes. Membrane morphology was observed by using a scanning electron microscopy (SEM). The SEM images illustrated that the increment of D-glucose monohydrate in casting solution tends to promote macrovoid formation. |
| first_indexed | 2025-11-15T21:06:45Z |
| format | Article |
| id | utm-9992 |
| institution | Universiti Teknologi Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T21:06:45Z |
| publishDate | 2009 |
| publisher | Penerbit UTM Press |
| recordtype | eprints |
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| spelling | utm-99922010-07-22T02:08:36Z http://eprints.utm.my/9992/ Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive Idris, Ani Hew, Ka Yee Chan, Mieow Kee TP Chemical technology Dialysis membrane containing cellulose acetate (CA) as polymer, formic acid (FA) as solvent and D-glucose monohydrate as additive was prepared by phase inversion method. The main objective of this study is to investigate the influence of D-glucose monohydrate as an additive on the performance of dialysis membrane in terms of urea and creatinine clearance. The concentration of D-glucose is varied from 2 to 10 wt%. Microwave heating which is capable of reducing dissolution time was used to dissolve the CA polymer in the formic acid solvent. Results revealed that the membrane produced from the 20 wt% cellulose acetate, 70 wt% formic acid and 10 wt% D-glucose monohydrate gives the best performance with urea and creatinine clearance of 49.77% and 19.54% respectively. When testing the same membranes with BSA solutions, it gives a BSA rejection rate as high as 96.78%, which seems to be comparable with the commercial cellulose acetate dialysis membranes. Membrane morphology was observed by using a scanning electron microscopy (SEM). The SEM images illustrated that the increment of D-glucose monohydrate in casting solution tends to promote macrovoid formation. Penerbit UTM Press 2009-12 Article PeerReviewed application/pdf en http://eprints.utm.my/9992/1/UTMjurnalTEK_51F_DIS%5B06%5D.pdf Idris, Ani and Hew, Ka Yee and Chan, Mieow Kee (2009) Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive. Jurnal Teknologi (Kejuruteraan) (51F). pp. 67-76. ISSN 0127-9696 http://www.penerbit.utm.my/onlinejournal/51/F/51sirif06.pdf |
| spellingShingle | TP Chemical technology Idris, Ani Hew, Ka Yee Chan, Mieow Kee Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive |
| title | Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive |
| title_full | Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive |
| title_fullStr | Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive |
| title_full_unstemmed | Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive |
| title_short | Preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive |
| title_sort | preparation of cellulose acetate dialysis membrane using d-glucose monohydrate as additive |
| topic | TP Chemical technology |
| url | http://eprints.utm.my/9992/ http://eprints.utm.my/9992/ http://eprints.utm.my/9992/1/UTMjurnalTEK_51F_DIS%5B06%5D.pdf |