On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil

A method for the on-line preconcentration and chiral separation of three chiral triazole fungicides, namely hexaconazole, penconazole and myclobutanil is reported. Simultaneous enantioseparation of the three triazole fungicides was successfully achieved by using CD-MEKC system containing 40 mM hydro...

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Main Author: Wan Ibrahim, Wan Aini
Format: Book Section
Published: Faculty of Science, Universiti Teknologi Malaysia 2009
Online Access:http://eprints.utm.my/9016/
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author Wan Ibrahim, Wan Aini
author_facet Wan Ibrahim, Wan Aini
author_sort Wan Ibrahim, Wan Aini
building UTeM Institutional Repository
collection Online Access
description A method for the on-line preconcentration and chiral separation of three chiral triazole fungicides, namely hexaconazole, penconazole and myclobutanil is reported. Simultaneous enantioseparation of the three triazole fungicides was successfully achieved by using CD-MEKC system containing 40 mM hydroxypropyl-γ-CD and 50 mM sodium dodecyl sulphate in 25 mM phosphate buffer (pH 3.0) solution. Stacking with a reverse migrating micelle (SRMM) and sweeping were used as two on-line preconcentration methods to enhance the concentration sensitivity. Results indicate that sweeping-CD-MEKC is better than SRMMCD-MEKC in terms of the sensitivity enhancement factor (SEF) of the three triazole fungicides. This is the first report on the simultaneous chiral separation of three triazole fungicides by on-line-CD-MEKC method.
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format Book Section
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institution Universiti Teknologi Malaysia
institution_category Local University
last_indexed 2025-11-15T21:03:34Z
publishDate 2009
publisher Faculty of Science, Universiti Teknologi Malaysia
recordtype eprints
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spelling utm-90162017-09-14T06:40:43Z http://eprints.utm.my/9016/ On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil Wan Ibrahim, Wan Aini A method for the on-line preconcentration and chiral separation of three chiral triazole fungicides, namely hexaconazole, penconazole and myclobutanil is reported. Simultaneous enantioseparation of the three triazole fungicides was successfully achieved by using CD-MEKC system containing 40 mM hydroxypropyl-γ-CD and 50 mM sodium dodecyl sulphate in 25 mM phosphate buffer (pH 3.0) solution. Stacking with a reverse migrating micelle (SRMM) and sweeping were used as two on-line preconcentration methods to enhance the concentration sensitivity. Results indicate that sweeping-CD-MEKC is better than SRMMCD-MEKC in terms of the sensitivity enhancement factor (SEF) of the three triazole fungicides. This is the first report on the simultaneous chiral separation of three triazole fungicides by on-line-CD-MEKC method. Faculty of Science, Universiti Teknologi Malaysia 2009-05 Book Section PeerReviewed Wan Ibrahim, Wan Aini (2009) On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil. In: Proceedings of Second International Conference and Workshops on Basic and Applied Sciences & Regional Annual Fundamental Science Seminar 2009. Faculty of Science, Universiti Teknologi Malaysia, . ISBN 978-983-9805-73-4
spellingShingle Wan Ibrahim, Wan Aini
On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil
title On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil
title_full On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil
title_fullStr On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil
title_full_unstemmed On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil
title_short On-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil
title_sort on-line preconcentration and cyclodextrin-modified micellar electrokinetic chromatography method for chiral separation of hexaconazole, penconazole and myclobutanil
url http://eprints.utm.my/9016/