A model for gene selection and classification of gene expression data
Gene expression data are expected to be of significant help in the development of efficient cancer diagnosis and classification platforms. One problem arising from these data is how to select a small subset of genes from thousands of genes and a few samples that are inherently noisy. This research a...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Japan
2007
|
| Subjects: | |
| Online Access: | http://eprints.utm.my/7392/ http://eprints.utm.my/7392/1/MohdSaberiMohamad2007_A%20modelforgeneselectionandclassificationofgene.pdf |
| _version_ | 1848891459273490432 |
|---|---|
| author | Mohamad, Mohd Saberi Omatu, Sigeru Deris, Safaai Mohd Hashim, Siti Zaiton |
| author_facet | Mohamad, Mohd Saberi Omatu, Sigeru Deris, Safaai Mohd Hashim, Siti Zaiton |
| author_sort | Mohamad, Mohd Saberi |
| building | UTeM Institutional Repository |
| collection | Online Access |
| description | Gene expression data are expected to be of significant help in the development of efficient cancer diagnosis and classification platforms. One problem arising from these data is how to select a small subset of genes from thousands of genes and a few samples that are inherently noisy. This research aims to select a small subset of informative genes from the gene expression data which will maximize the classification accuracy. A model for gene selection and classification has been developed by using a filter approach, and an improved hybrid of the genetic algorithm and a support vector machine classifier. We show that the classification accuracy of the proposed model is useful for the cancer classification of one widely used gene expression benchmark data set |
| first_indexed | 2025-11-15T20:58:18Z |
| format | Article |
| id | utm-7392 |
| institution | Universiti Teknologi Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T20:58:18Z |
| publishDate | 2007 |
| publisher | Springer Japan |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | utm-73922017-03-14T06:49:59Z http://eprints.utm.my/7392/ A model for gene selection and classification of gene expression data Mohamad, Mohd Saberi Omatu, Sigeru Deris, Safaai Mohd Hashim, Siti Zaiton TA Engineering (General). Civil engineering (General) Gene expression data are expected to be of significant help in the development of efficient cancer diagnosis and classification platforms. One problem arising from these data is how to select a small subset of genes from thousands of genes and a few samples that are inherently noisy. This research aims to select a small subset of informative genes from the gene expression data which will maximize the classification accuracy. A model for gene selection and classification has been developed by using a filter approach, and an improved hybrid of the genetic algorithm and a support vector machine classifier. We show that the classification accuracy of the proposed model is useful for the cancer classification of one widely used gene expression benchmark data set Springer Japan 2007 Article PeerReviewed application/pdf en http://eprints.utm.my/7392/1/MohdSaberiMohamad2007_A%20modelforgeneselectionandclassificationofgene.pdf Mohamad, Mohd Saberi and Omatu, Sigeru and Deris, Safaai and Mohd Hashim, Siti Zaiton (2007) A model for gene selection and classification of gene expression data. Artificial Life and Robotics, 11 (2). pp. 219-222. ISSN 1614-7456 http://dx.doi.org/10.1007/s10015-007-0432-1 10.1007/s10015-007-0432-1 |
| spellingShingle | TA Engineering (General). Civil engineering (General) Mohamad, Mohd Saberi Omatu, Sigeru Deris, Safaai Mohd Hashim, Siti Zaiton A model for gene selection and classification of gene expression data |
| title | A model for gene selection and classification of gene expression data |
| title_full | A model for gene selection and classification of gene expression data |
| title_fullStr | A model for gene selection and classification of gene expression data |
| title_full_unstemmed | A model for gene selection and classification of gene expression data |
| title_short | A model for gene selection and classification of gene expression data |
| title_sort | model for gene selection and classification of gene expression data |
| topic | TA Engineering (General). Civil engineering (General) |
| url | http://eprints.utm.my/7392/ http://eprints.utm.my/7392/ http://eprints.utm.my/7392/ http://eprints.utm.my/7392/1/MohdSaberiMohamad2007_A%20modelforgeneselectionandclassificationofgene.pdf |