Characterization of cyclodextrin complexes with turmeric oleoresin

Turmeric rhizome oleoresin (TRO) was successfully solubilised in aqueous solution by forming inclusion complexes with β-cyclodextrin (BCD) and γ-cyclodextrin (GCD). To investigate molecular associations of BCD and/or GCD with the oleoresin, phase solubility studies were undertaken, using 1,8-cineo...

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Main Authors: Haiyee, Zaibunnisa Abdul, Saim, Norashikin, Said, Mamot, Illias, Rosli Md., Mustapha, Wan Aida Wan, Hassan, Osman
Format: Article
Published: Elsevier Ltd. 2008
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Online Access:http://eprints.utm.my/7272/
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author Haiyee, Zaibunnisa Abdul
Saim, Norashikin
Said, Mamot
Illias, Rosli Md.
Mustapha, Wan Aida Wan
Hassan, Osman
author_facet Haiyee, Zaibunnisa Abdul
Saim, Norashikin
Said, Mamot
Illias, Rosli Md.
Mustapha, Wan Aida Wan
Hassan, Osman
author_sort Haiyee, Zaibunnisa Abdul
building UTeM Institutional Repository
collection Online Access
description Turmeric rhizome oleoresin (TRO) was successfully solubilised in aqueous solution by forming inclusion complexes with β-cyclodextrin (BCD) and γ-cyclodextrin (GCD). To investigate molecular associations of BCD and/or GCD with the oleoresin, phase solubility studies were undertaken, using 1,8-cineole (C10H18O) and ar-tumerone (C15H20O) as marker compounds to represent turmeric oleoresin. In the presence of cyclodextrins, the solubility of 1,8-cineole and ar-tumerone were enhanced. Based on the stability constant, k1:1, the GCD-complex was at least twice effective than BCD. Solid state inclusion complexes were also prepared, using kneading (K) and co-precipitation (CP) methods, and analysed using Fourier transform infrared (FTIR) spectrometry and scanning electron microscopy (SEM). The shift of C{double bond, long}O stretching to higher wavenumbers and strengthening of the C{single bond}O stretching band indicated the formation of a complex between CD and TRO. The new solid phase formed using the co-precipitation method, had a crystal structure which was completely different from the original morphology of oleoresin and cyclodextrins.
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spelling utm-72722017-10-22T08:53:01Z http://eprints.utm.my/7272/ Characterization of cyclodextrin complexes with turmeric oleoresin Haiyee, Zaibunnisa Abdul Saim, Norashikin Said, Mamot Illias, Rosli Md. Mustapha, Wan Aida Wan Hassan, Osman TP Chemical technology Turmeric rhizome oleoresin (TRO) was successfully solubilised in aqueous solution by forming inclusion complexes with β-cyclodextrin (BCD) and γ-cyclodextrin (GCD). To investigate molecular associations of BCD and/or GCD with the oleoresin, phase solubility studies were undertaken, using 1,8-cineole (C10H18O) and ar-tumerone (C15H20O) as marker compounds to represent turmeric oleoresin. In the presence of cyclodextrins, the solubility of 1,8-cineole and ar-tumerone were enhanced. Based on the stability constant, k1:1, the GCD-complex was at least twice effective than BCD. Solid state inclusion complexes were also prepared, using kneading (K) and co-precipitation (CP) methods, and analysed using Fourier transform infrared (FTIR) spectrometry and scanning electron microscopy (SEM). The shift of C{double bond, long}O stretching to higher wavenumbers and strengthening of the C{single bond}O stretching band indicated the formation of a complex between CD and TRO. The new solid phase formed using the co-precipitation method, had a crystal structure which was completely different from the original morphology of oleoresin and cyclodextrins. Elsevier Ltd. 2008 Article PeerReviewed Haiyee, Zaibunnisa Abdul and Saim, Norashikin and Said, Mamot and Illias, Rosli Md. and Mustapha, Wan Aida Wan and Hassan, Osman (2008) Characterization of cyclodextrin complexes with turmeric oleoresin. Food Chemistry . ISSN 0308-8146 http://dx.doi.org/10.1016/j.foodchem.2008.09.072 10.1016/j.foodchem.2008.09.072
spellingShingle TP Chemical technology
Haiyee, Zaibunnisa Abdul
Saim, Norashikin
Said, Mamot
Illias, Rosli Md.
Mustapha, Wan Aida Wan
Hassan, Osman
Characterization of cyclodextrin complexes with turmeric oleoresin
title Characterization of cyclodextrin complexes with turmeric oleoresin
title_full Characterization of cyclodextrin complexes with turmeric oleoresin
title_fullStr Characterization of cyclodextrin complexes with turmeric oleoresin
title_full_unstemmed Characterization of cyclodextrin complexes with turmeric oleoresin
title_short Characterization of cyclodextrin complexes with turmeric oleoresin
title_sort characterization of cyclodextrin complexes with turmeric oleoresin
topic TP Chemical technology
url http://eprints.utm.my/7272/
http://eprints.utm.my/7272/
http://eprints.utm.my/7272/