Evaluation of pharmaceutical cream production debottlenecking schemes
The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increas...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
2005
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| Subjects: | |
| Online Access: | http://eprints.utm.my/5366/ http://eprints.utm.my/5366/1/JullyTan2005_EvaluationOfPharmaceuticalCreamProduction.pdf |
| _version_ | 1848891034627473408 |
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| author | Tan, Jully Foo, Dominic Chwan Yee Kumaresan, Sivakumar Abdul Aziz, Ramlan |
| author_facet | Tan, Jully Foo, Dominic Chwan Yee Kumaresan, Sivakumar Abdul Aziz, Ramlan |
| author_sort | Tan, Jully |
| building | UTeM Institutional Repository |
| collection | Online Access |
| description | The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increase of the product demand of 150% in the market. By carrying out throughput analysis study, schemes that fulfil the debottlenecking objective were determined. Out of the four debottlenecking schemes, Scheme 4 was chosen, which proposed a new blending tank and intermediate tank, showed a production increase of over 150%. |
| first_indexed | 2025-11-15T20:51:33Z |
| format | Conference or Workshop Item |
| id | utm-5366 |
| institution | Universiti Teknologi Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T20:51:33Z |
| publishDate | 2005 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | utm-53662010-06-01T15:29:45Z http://eprints.utm.my/5366/ Evaluation of pharmaceutical cream production debottlenecking schemes Tan, Jully Foo, Dominic Chwan Yee Kumaresan, Sivakumar Abdul Aziz, Ramlan T Technology (General) The main objective of this work is to model and debottleneck a pharmaceutical production of an anti-allergic cream. The base case process has a minimum cycle time of 29 hours which is equivalent to 66 batches/year. Four schemes were proposed for process debottlenecking due to the anticipated increase of the product demand of 150% in the market. By carrying out throughput analysis study, schemes that fulfil the debottlenecking objective were determined. Out of the four debottlenecking schemes, Scheme 4 was chosen, which proposed a new blending tank and intermediate tank, showed a production increase of over 150%. 2005 Conference or Workshop Item PeerReviewed application/pdf en http://eprints.utm.my/5366/1/JullyTan2005_EvaluationOfPharmaceuticalCreamProduction.pdf Tan, Jully and Foo, Dominic Chwan Yee and Kumaresan, Sivakumar and Abdul Aziz, Ramlan (2005) Evaluation of pharmaceutical cream production debottlenecking schemes. In: International Symposium On Design, Operation and Control Of Chemical Processes 2005, 13-15 August 2005, Seoul, Korea. |
| spellingShingle | T Technology (General) Tan, Jully Foo, Dominic Chwan Yee Kumaresan, Sivakumar Abdul Aziz, Ramlan Evaluation of pharmaceutical cream production debottlenecking schemes |
| title | Evaluation of pharmaceutical cream production debottlenecking schemes |
| title_full | Evaluation of pharmaceutical cream production debottlenecking schemes |
| title_fullStr | Evaluation of pharmaceutical cream production debottlenecking schemes |
| title_full_unstemmed | Evaluation of pharmaceutical cream production debottlenecking schemes |
| title_short | Evaluation of pharmaceutical cream production debottlenecking schemes |
| title_sort | evaluation of pharmaceutical cream production debottlenecking schemes |
| topic | T Technology (General) |
| url | http://eprints.utm.my/5366/ http://eprints.utm.my/5366/1/JullyTan2005_EvaluationOfPharmaceuticalCreamProduction.pdf |