Î²-sheet containment by flanking prolines: Molecular Dynamic Simulations of the inhibition of Î²-sheet elongation by proline residues in human prion protein.

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Î²-sheet containment by flanking prolines: Molecular Dynamic Simulations of the inhibition of Î²-sheet elongation by proline residues in human prion protein.

Previous molecular dynamic simulations have reported elongation of the existing Î²-sheet in prion proteins. Detailed examination has shown that these elongations do not extend beyond the proline residues flanking these Î²-sheets. In addition, proline has also been suggested to possess a possible str...

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Bibliographic Details
Main Authors:	Shamsir, Mohd Shahir, Dalby, Andrew
Format:	Article
Language:	English
Published:	Biophysical Society 2007
Subjects:	Q Science (General) QH301 Biology
Online Access:	http://eprints.utm.my/462/ http://eprints.utm.my/462/1/Flanking-2.pdf

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